Fabrication and Characterization of Calcium Carbonate Microspheres

Bibliographic Details
Format: Restricted Document
_version_ 1860799405160923136
building INTELEK Repository
caption ICSR 2012
collection Online Access
collectionurl https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
date 2015-04-05 16:06:07
eventvenue Universiti Sultan Zainal Abidin
format Restricted Document
id 5877
institution UniSZA
originalfilename 0583-01-FH03-FSTK-16-04924.pdf
person Babak D. Safa
recordtype oai_dc
resourceurl https://intelek.unisza.edu.my/intelek/pages/view.php?ref=5877
spelling 5877 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=5877 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Conference Conference Paper application/pdf 12 1.6 Adobe Acrobat Pro DC 20 Paper Capture Plug-in Babak D. Safa ICSR 2012 ICSR Iran Seismic Retrofitting Earthquake Engineering ICSR 2012 2015-04-05 16:06:07 0583-01-FH03-FSTK-16-04924.pdf UniSZA Private Access Fabrication and Characterization of Calcium Carbonate Microspheres Calcium carbonate (CaCO3) microspheres (μ-spheres) are widely used inorganic templates (or cores) for fabricating nano-engineered microcapsules. In the current work, fabrication of CaCO3 μ-spheres was carried out using precipitation reaction between calcium chloride (CaCl2) and sodium carbonate (Na2CO3) solutions under vigorous stirring. Two different fabrication approaches were used, namely membrane filtration and centrifugation approaches, in order to prepare spherical CaCO3 μ-spheres with a narrow size distribution. Several different experimental factors can affect the size and shape of CaCO3 μ-spheres. For the membrane filtration approach, the experimental factors tested included mixing procedure of solutions, stirring speeds, drying techniques, and types of filter paper used. For the centrifugation approach, the experimental factors tested included mixing procedure of solutions, stirring speeds, centrifugation times, drying techniques, and quantity of washing agents used. The size measurements and shape of the CaCO3 μ-spheres were investigated using compound microscopy. Scanning electron microscopy (SEM) was used to reveal the fine surface morphological details of the CaCO3 μ-spheres. Overall results indicate that the centrifugation approach can yield better CaCO3 μ-spheres as compared to the membrane filtration approach in terms of narrow size distribution and spherical shape. The CaCO3 μ-spheres will be used as templates for fabricating nano-engineered dynamic microcapsules (DynaMicCaps) containing calmodulin (CaM) protein for drug delivery applications. Proceedings of the UniSZA Research Conference 2015 (URC ’15) Universiti Sultan Zainal Abidin
spellingShingle Fabrication and Characterization of Calcium Carbonate Microspheres
subject ICSR 2012
summary Calcium carbonate (CaCO3) microspheres (μ-spheres) are widely used inorganic templates (or cores) for fabricating nano-engineered microcapsules. In the current work, fabrication of CaCO3 μ-spheres was carried out using precipitation reaction between calcium chloride (CaCl2) and sodium carbonate (Na2CO3) solutions under vigorous stirring. Two different fabrication approaches were used, namely membrane filtration and centrifugation approaches, in order to prepare spherical CaCO3 μ-spheres with a narrow size distribution. Several different experimental factors can affect the size and shape of CaCO3 μ-spheres. For the membrane filtration approach, the experimental factors tested included mixing procedure of solutions, stirring speeds, drying techniques, and types of filter paper used. For the centrifugation approach, the experimental factors tested included mixing procedure of solutions, stirring speeds, centrifugation times, drying techniques, and quantity of washing agents used. The size measurements and shape of the CaCO3 μ-spheres were investigated using compound microscopy. Scanning electron microscopy (SEM) was used to reveal the fine surface morphological details of the CaCO3 μ-spheres. Overall results indicate that the centrifugation approach can yield better CaCO3 μ-spheres as compared to the membrane filtration approach in terms of narrow size distribution and spherical shape. The CaCO3 μ-spheres will be used as templates for fabricating nano-engineered dynamic microcapsules (DynaMicCaps) containing calmodulin (CaM) protein for drug delivery applications.
title Fabrication and Characterization of Calcium Carbonate Microspheres
title_full Fabrication and Characterization of Calcium Carbonate Microspheres
title_fullStr Fabrication and Characterization of Calcium Carbonate Microspheres
title_full_unstemmed Fabrication and Characterization of Calcium Carbonate Microspheres
title_short Fabrication and Characterization of Calcium Carbonate Microspheres
title_sort fabrication and characterization of calcium carbonate microspheres