2015_Pharmacogenovigilance in Drug Safety: Knowledge Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia
| Format: | General Document |
|---|
| _version_ | 1860798019518070784 |
|---|---|
| building | INTELEK Repository |
| collection | Online Access |
| collectionurl | https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection3 |
| copyright | Copyright©PWB2025 |
| country | Malaysia |
| date | 2015-11-25 |
| format | General Document |
| id | 15498 |
| institution | UniSZA |
| internalnotes | Sila masukkan subject wajib Dissertations, Academic. Terima kasih... |
| originalfilename | PHARMACOGENOVIGILANCE IN DRUG SAFETY_ KNOWLEDGE ATTITUDES AND PRACTICE AMONG FINAL-YEAR MEDICAL AND PHARMACY STUDENTS IN PENINSULAR MALAYSIA (MASTER_2015).pdf |
| person | Adamu Yau |
| recordtype | oai_dc |
| resourceurl | https://intelek.unisza.edu.my/intelek/pages/view.php?ref=15498 |
| sourcemedia | Server storage Scanned document |
| spelling | 15498 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=15498 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection3 General Document Malaysia Library Staff (Top Management) Library Staff (Management) Library Staff (Support) Terengganu Faculty of Medicine English application/pdf 1.5 Server storage Scanned document Universiti Sultan Zainal Abidin UniSZA Private Access Universiti Sultan Zainal Abidin SAMBox 2.3.4; modified using iTextSharp™ 5.5.10 ©2000-2016 iText Group NV (AGPL-version) 146 PHARMACOGENOVIGILANCE IN DRUG SAFETY_ KNOWLEDGE ATTITUDES AND PRACTICE AMONG FINAL-YEAR MEDICAL AND PHARMACY STUDENTS IN PENINSULAR MALAYSIA (MASTER_2015).pdf 2015_Pharmacogenovigilance in Drug Safety: Knowledge Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia Copyright©PWB2025 Adamu Yau 2015-11-25 Pharmacogenovigilance—Research Pharmacogenovigilance Integration of pharmacogenomics and pharmacovigilance in the academic curricula of future healthcare professionals is important as the knowledge and training are prerequisite to professionalism. Pharmacogenomics provide a greener future to individualized medicine and drug safety, but to reap these benefits it requires good pharmacogenovigilance knowledge, attitude and practice (KAP) among current and future healthcare professionals. This study aimed at getting in-sight to the knowledge, attitude and practice of final-year medical and pharmacy students towards pharmacogenomics and pharmacovigilance in drug safety and also to develop a reliable and valid KAP questionnaire on pharmacogenovigilance in drug safety. A 59 items self-administered questionnaire was developed from literature and expert opinion. It was subjected to content validity study by 7 relevant experts, and followed by face validity study (FVI) involving 20 respondents. The questionnaire was then distributed to 247 participants for validation study using exploratory factor analysis. It was then piloted on 100 participants for retest and reliability tests. Post-validated questionnaire was administered to 465 participants for KAP assessment. Descriptive statistics were used to present demographic information. The associations between knowledge and practice, attitude and practice, with demographic variables were analyzed using Chi-square test and one way ANOVA. Seventy percent of respondents were females, 82.07% were medical students with mean age 22.98±1.03 years old. The Content Validity Index and Face Validity Index of the whole questionnaires were 0.82% and 0.82% respectively. Bartlett’s test of sphericity value (KMO) was 0.775 with P<0.001. Based on factor analysis, three factors were extracted and 67.46% of total variance was explained by 13 factors. The independent t-test revealed that, the mean knowledge and attitude scores among final-year pharmacy students were 89.20±SD8.86% and 73.7±6.59%, and that of final-year medical students were 84.95±13.2% and 69.7±7.74% respectively, with a statistical significant difference (p value<0.001 at 95% CI). A low level of practice was observed with a statistically significant difference between pharmacy and medical students (P<0.05). Findings revealed that the questionnaire was valid and reliable instrument that could be used for the same purpose under the same condition. The majority demonstrated good knowledge and attitude towards pharmacogenovigilance in drug safety, but with low level of practice. These findings show the readiness of the participated final-year medical and pharmacy students towards any pharmacogenomic based challenges and integration of Pharmacogenomics into practice. Dissertations, Academic Sila masukkan subject wajib Dissertations, Academic. Terima kasih... Knowledge, Attitudes, And Practices (KAP) Pharmacy Students Thesis |
| spellingShingle | 2015_Pharmacogenovigilance in Drug Safety: Knowledge Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia |
| state | Terengganu |
| subject | Pharmacogenovigilance—Research Dissertations, Academic |
| summary | Integration of pharmacogenomics and pharmacovigilance in the academic curricula of future healthcare professionals is important as the knowledge and training are prerequisite to professionalism. Pharmacogenomics provide a greener future to individualized medicine and drug safety, but to reap these benefits it requires good pharmacogenovigilance knowledge, attitude and practice (KAP) among current and future healthcare professionals. This study aimed at getting in-sight to the knowledge, attitude and practice of final-year medical and pharmacy students towards pharmacogenomics and pharmacovigilance in drug safety and also to develop a reliable and valid KAP questionnaire on pharmacogenovigilance in drug safety. A 59 items self-administered questionnaire was developed from literature and expert opinion. It was subjected to content validity study by 7 relevant experts, and followed by face validity study (FVI) involving 20 respondents. The questionnaire was then distributed to 247 participants for validation study using exploratory factor analysis. It was then piloted on 100 participants for retest and reliability tests. Post-validated questionnaire was administered to 465 participants for KAP assessment. Descriptive statistics were used to present demographic information. The associations between knowledge and practice, attitude and practice, with demographic variables were analyzed using Chi-square test and one way ANOVA. Seventy percent of respondents were females, 82.07% were medical students with mean age 22.98±1.03 years old. The Content Validity Index and Face Validity Index of the whole questionnaires were 0.82% and 0.82% respectively. Bartlett’s test of sphericity value (KMO) was 0.775 with P<0.001. Based on factor analysis, three factors were extracted and 67.46% of total variance was explained by 13 factors. The independent t-test revealed that, the mean knowledge and attitude scores among final-year pharmacy students were 89.20±SD8.86% and 73.7±6.59%, and that of final-year medical students were 84.95±13.2% and 69.7±7.74% respectively, with a statistical significant difference (p value<0.001 at 95% CI). A low level of practice was observed with a statistically significant difference between pharmacy and medical students (P<0.05). Findings revealed that the questionnaire was valid and reliable instrument that could be used for the same purpose under the same condition. The majority demonstrated good knowledge and attitude towards pharmacogenovigilance in drug safety, but with low level of practice. These findings show the readiness of the participated final-year medical and pharmacy students towards any pharmacogenomic based challenges and integration of Pharmacogenomics into practice. |
| title | 2015_Pharmacogenovigilance in Drug Safety: Knowledge Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia |
| title_full | 2015_Pharmacogenovigilance in Drug Safety: Knowledge Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia |
| title_fullStr | 2015_Pharmacogenovigilance in Drug Safety: Knowledge Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia |
| title_full_unstemmed | 2015_Pharmacogenovigilance in Drug Safety: Knowledge Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia |
| title_short | 2015_Pharmacogenovigilance in Drug Safety: Knowledge Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia |
| title_sort | 2015_pharmacogenovigilance in drug safety: knowledge attitudes and practice among final-year medical and pharmacy students in peninsular malaysia |