| _version_ |
1860797975905697792
|
| building |
INTELEK Repository
|
| collection |
Online Access
|
| collectionurl |
https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
|
| date |
2024-08-30 11:13:37
|
| format |
Restricted Document
|
| id |
15223
|
| institution |
UniSZA
|
| internalnotes |
1. Garrod Archibald E. The Incidence of Alkaptonuria: Astudy in Chemical Individuality. Lancet, 1902;2(3):1616–20. 2. Goldstein DB, Need AC, Singh R, Sisodiya SM. Potential Genetic Causes of Heterogeneity of Treatment Effects. Am J Med, 2007;120(4 SUPPL.). 3. Scheuner MT, Sieverding P, Paul G. Shekelle. Delivery of Genomic Medicine A Systematic Review. JAMA, 2008;299(11):1320–34. 4. Suther SG, Goodson P. Texas physicians’ perceptions of genomic medicine as an innovation. Clin Genet. 2004;65(5):368–77. 5. Billings P, Carlson R, J Carlson, M C, C W, P S, et al. Ready for Genomic Medicine? Perspectives of Health Care Decision Makers. Arch Intern Med, 2005;165(16):1917–9. 6. Klitzman R, Chung W, Marder K, Shanmugham A, Lisa J. Chin J, Stark M, et al. Attitudes and Practices Among Internists Concerning Genetic Testing. J Genet Couns, 2014;22(1):90–100. 7. Nippert I, Harris HJ, Julian-Reynier C, Kristoffersson U, Kate LP Ten, Anionwu E, et al. Confidence of primary care physicians in their ability to carry out basic medical genetic tasks- A European survey in five countries-Part 1. J Community Genet, 2011;2(1):1–11. 8. Friedman LC, Cooper HP, Webb JA, Weinberg AD, Plon SE. Primary care physicians’ attitudes and practices regarding cancer genetics: a comparison of 2001 with 1996 survey results. J Cancer Educ, 2003;18(2):91–4. 9. Gage BF, Lesko LJ. PG of warfarin: Regulatory, scientific, and clinical issues. J Thromb Thrombolysis, 2008;25(1):45–51. 10. Bannur Z, S B, MZ S, LK T. Pharmacogenomics Based Practice in Malaysia : The Attitude , Knowledge and Adoption by the Healthcare Demographics of Respondents. IMJM, 2014;13(1):41–50. 11. Sadee W. Genomics and personalized medicine. Int J Pharm, 2011;415(1-2):2–4. 12. Bakhouche H, Slanař O. PG in clinical practice. Prague Med Rep, 2012;113(4):251–61. 13. Brockmöller J, Tzvetkov M V. Pharmacogenetics: Data, concepts and tools to improve drug discovery and drug treatment. Eur J Clin Pharmacol, 2008;64(2):133–57. 14. Ginsburg GS, Willard HF. Genomic and personalized medicine: foundations and applications. Transl Res, 2009;154(6):277–87. 15. Shields AE, Blumenthal D, Weiss KB, Comstock CB, Currivan D, Lerman C. Barriers to translating emerging genetic research on smoking into clinical practice. Perspectives of primary care physicians. J Gen Intern Med, 2005;20(2):131–8. 16. Powell KP, Cogswell W a, Christianson C a, Dave G, Verma A, Eubanks S, et al. Primary care physicians’ awareness, experience and opinions of direct-to-consumer genetic testing. J Genet Couns [Internet], 2012 Feb [cited 2014 Dec 15];21(1):113– 26. 17. Haga SB, Burke W, Ginsburg GS, Mills R, Agans R. Primary Care Physicians’ Knowledge of and Experience with Pharmacogenetic Testing. Clin Genet [Internet], 2013;82(4):388–94. 18. Stanek EJ, Sanders CL, Taber K a J, Khalid M, Patel a, Verbrugge RR, et al. Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey. Clin Pharmacol Ther [Internet], Nature Publishing Group; 2012 Mar [cited 2014 Dec 15];91(3):450–8. 19. Stanek E, Sanders C, Frueh F. Physician Awareness and Utilization of Food and Drug Administration (FDA)-Approved Labeling for Pharmacogenomic Testing Information. J Pers Med [Internet], 2013 Jun 10 [cited 2014 Dec 15];3(2):111–23. 20. Hamilton AB, Oishi S, Yano EM, Gammage CE, Marshall NJ, Scheuner MT. Factors influencing organizational adoption and implementation of clinical genetic services. Genet Med [Internet], 2014;16(3):238–45. 21. Peppercorn J, Hamilton E, Marcom PK, Beskow L, Lyman GH. Pharmacogenetic testing in the face of unclear clinical efficacy: lessons from cytochrome P450 2D6 for tamoxifen. Cancer [Internet], 2013 Oct 15 [cited 2014 Dec 15];119(20):3703–9. 22. Taber J, Press D. Pharmacogenomic knowledge gaps and educational resource needs among physicians in selected specialties. Pharmgenomics Pers Med [Internet], 2014;7:145–62. 23. Dressler LG, Deal AM, Patel J, Markey J, Riper M Van, McLeod HL. Cancer Pharmacogenomics, Adoption by Oncologists and Patient Benefit. Per Med [Internet], 2014;11(2):143–53. 24. Bonter K, Desjardins C, Currier N, Pun J, Ashbury FD. Personalised medicine in Canada: a survey of adoption and practice in oncology, cardiology and family medicine. BMJ Open [Internet], 2011 Jan 1 [cited 2014 Dec 6];1(1):e000110. 25. Ohata T, Tsuchiya A, Watanabe M, Sumida T, Takada F. Physicians’ opinion for “new” genetic testing in Japan. J Hum Genet [Internet], 2009 Apr [cited 2014 Dec 15];54(4):203–8. 26. 26. Rogausch A, Prause D, Schallenberg A, Brockmöller J, Himmel W. Patients’ and physicians' perspectives on pharmacogenetic testing. Pharmacogenomics [Internet], 2006 Jan;7(1):49–59. 27. Baars MJH, Henneman L, ten Kate LP. Deficiency of knowledge of genetics and genetic tests among general practitioners, gynecologists, and pediatricians: A global problem [Internet]. Genetics in Medicine, 2005 [cited 2014 Dec 3]. p. 605–10. 28. Bernhardt BA, Zayac C, Gordon ES, Wawak L, Pyeritz RE, Gollust SE. Incorporating direct-toconsumer genomic information into patient care: attitudes and experiences of primary care physicians. Per Med [Internet], 2012;9(7):683–92.
|
| originalfilename |
5986-01-FH02-FP-15-03248.pdf
|
| person |
Compaq
|
| recordtype |
oai_dc
|
| resourceurl |
https://intelek.unisza.edu.my/intelek/pages/view.php?ref=15223
|
| spelling |
15223 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=15223 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf Adobe Acrobat Pro DC 20 Paper Capture Plug-in with ClearScan 9 1.6 Compaq 2024-08-30 11:13:37 5986-01-FH02-FP-15-03248.pdf UniSZA Private Access A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors International Journal of Pharmaceutical Research Background: Adverse drug events are public health problem that deserves special attention. The drug and its dosage can be tailored to the individual patient’s need and can solve many drug related problems if genetic factors are taken into account appropriately before initiating medications. Doctors are increasingly expected to integrate genomic medicine into routine patient care. The genomic incorporation yet not achieved public health expectations. This review analyses and summarises the various studies done on KAP towards pharmacogenomics. Methods: Fifteen KAP studies conducted on pharmacogenetics among doctors covered from 2004 to 2014 were selected. Studies conducted on doctors of different specialties were selected. This review exclude theoretical articles, studies done on general public; studies conducted on other healthcare professionals; and also studies conducted on genetics of diseases. Results: Knowledge and practice regarding pharmacogenetics among doctors were poor despite good attitudes. Several studies revealed factors that influence integration of pharmacogenetics into patient care with interventional recommendations. Conclusion: There is a critical need for additional training on pharmacogenomics among doctors and also to incorporate it into medical school curriculum. Emphasis should be placed on how to accurately interpret and critically evaluate the use, and safety of pharmacogenetic testing. 7 1 9-16 1. Garrod Archibald E. The Incidence of Alkaptonuria: Astudy in Chemical Individuality. Lancet, 1902;2(3):1616–20. 2. Goldstein DB, Need AC, Singh R, Sisodiya SM. Potential Genetic Causes of Heterogeneity of Treatment Effects. Am J Med, 2007;120(4 SUPPL.). 3. Scheuner MT, Sieverding P, Paul G. Shekelle. Delivery of Genomic Medicine A Systematic Review. JAMA, 2008;299(11):1320–34. 4. Suther SG, Goodson P. Texas physicians’ perceptions of genomic medicine as an innovation. Clin Genet. 2004;65(5):368–77. 5. Billings P, Carlson R, J Carlson, M C, C W, P S, et al. Ready for Genomic Medicine? Perspectives of Health Care Decision Makers. Arch Intern Med, 2005;165(16):1917–9. 6. Klitzman R, Chung W, Marder K, Shanmugham A, Lisa J. Chin J, Stark M, et al. Attitudes and Practices Among Internists Concerning Genetic Testing. J Genet Couns, 2014;22(1):90–100. 7. Nippert I, Harris HJ, Julian-Reynier C, Kristoffersson U, Kate LP Ten, Anionwu E, et al. Confidence of primary care physicians in their ability to carry out basic medical genetic tasks- A European survey in five countries-Part 1. J Community Genet, 2011;2(1):1–11. 8. Friedman LC, Cooper HP, Webb JA, Weinberg AD, Plon SE. Primary care physicians’ attitudes and practices regarding cancer genetics: a comparison of 2001 with 1996 survey results. J Cancer Educ, 2003;18(2):91–4. 9. Gage BF, Lesko LJ. PG of warfarin: Regulatory, scientific, and clinical issues. J Thromb Thrombolysis, 2008;25(1):45–51. 10. Bannur Z, S B, MZ S, LK T. Pharmacogenomics Based Practice in Malaysia : The Attitude , Knowledge and Adoption by the Healthcare Demographics of Respondents. IMJM, 2014;13(1):41–50. 11. Sadee W. Genomics and personalized medicine. Int J Pharm, 2011;415(1-2):2–4. 12. Bakhouche H, Slanař O. PG in clinical practice. Prague Med Rep, 2012;113(4):251–61. 13. Brockmöller J, Tzvetkov M V. Pharmacogenetics: Data, concepts and tools to improve drug discovery and drug treatment. Eur J Clin Pharmacol, 2008;64(2):133–57. 14. Ginsburg GS, Willard HF. Genomic and personalized medicine: foundations and applications. Transl Res, 2009;154(6):277–87. 15. Shields AE, Blumenthal D, Weiss KB, Comstock CB, Currivan D, Lerman C. Barriers to translating emerging genetic research on smoking into clinical practice. Perspectives of primary care physicians. J Gen Intern Med, 2005;20(2):131–8. 16. Powell KP, Cogswell W a, Christianson C a, Dave G, Verma A, Eubanks S, et al. Primary care physicians’ awareness, experience and opinions of direct-to-consumer genetic testing. J Genet Couns [Internet], 2012 Feb [cited 2014 Dec 15];21(1):113– 26. 17. Haga SB, Burke W, Ginsburg GS, Mills R, Agans R. Primary Care Physicians’ Knowledge of and Experience with Pharmacogenetic Testing. Clin Genet [Internet], 2013;82(4):388–94. 18. Stanek EJ, Sanders CL, Taber K a J, Khalid M, Patel a, Verbrugge RR, et al. Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey. Clin Pharmacol Ther [Internet], Nature Publishing Group; 2012 Mar [cited 2014 Dec 15];91(3):450–8. 19. Stanek E, Sanders C, Frueh F. Physician Awareness and Utilization of Food and Drug Administration (FDA)-Approved Labeling for Pharmacogenomic Testing Information. J Pers Med [Internet], 2013 Jun 10 [cited 2014 Dec 15];3(2):111–23. 20. Hamilton AB, Oishi S, Yano EM, Gammage CE, Marshall NJ, Scheuner MT. Factors influencing organizational adoption and implementation of clinical genetic services. Genet Med [Internet], 2014;16(3):238–45. 21. Peppercorn J, Hamilton E, Marcom PK, Beskow L, Lyman GH. Pharmacogenetic testing in the face of unclear clinical efficacy: lessons from cytochrome P450 2D6 for tamoxifen. Cancer [Internet], 2013 Oct 15 [cited 2014 Dec 15];119(20):3703–9. 22. Taber J, Press D. Pharmacogenomic knowledge gaps and educational resource needs among physicians in selected specialties. Pharmgenomics Pers Med [Internet], 2014;7:145–62. 23. Dressler LG, Deal AM, Patel J, Markey J, Riper M Van, McLeod HL. Cancer Pharmacogenomics, Adoption by Oncologists and Patient Benefit. Per Med [Internet], 2014;11(2):143–53. 24. Bonter K, Desjardins C, Currier N, Pun J, Ashbury FD. Personalised medicine in Canada: a survey of adoption and practice in oncology, cardiology and family medicine. BMJ Open [Internet], 2011 Jan 1 [cited 2014 Dec 6];1(1):e000110. 25. Ohata T, Tsuchiya A, Watanabe M, Sumida T, Takada F. Physicians’ opinion for “new” genetic testing in Japan. J Hum Genet [Internet], 2009 Apr [cited 2014 Dec 15];54(4):203–8. 26. 26. Rogausch A, Prause D, Schallenberg A, Brockmöller J, Himmel W. Patients’ and physicians' perspectives on pharmacogenetic testing. Pharmacogenomics [Internet], 2006 Jan;7(1):49–59. 27. Baars MJH, Henneman L, ten Kate LP. Deficiency of knowledge of genetics and genetic tests among general practitioners, gynecologists, and pediatricians: A global problem [Internet]. Genetics in Medicine, 2005 [cited 2014 Dec 3]. p. 605–10. 28. Bernhardt BA, Zayac C, Gordon ES, Wawak L, Pyeritz RE, Gollust SE. Incorporating direct-toconsumer genomic information into patient care: attitudes and experiences of primary care physicians. Per Med [Internet], 2012;9(7):683–92.
|
| spellingShingle |
A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors
|
| summary |
Background: Adverse drug events are public health problem that deserves special attention. The drug and its dosage can be tailored to the individual patient’s need and can solve many drug related problems if genetic factors are taken into account appropriately before initiating medications. Doctors are increasingly expected to integrate genomic medicine into routine patient care. The genomic incorporation yet not achieved public health expectations. This review analyses and summarises the various studies done on KAP towards pharmacogenomics. Methods: Fifteen KAP studies conducted on pharmacogenetics among doctors covered from 2004 to 2014 were selected. Studies conducted on doctors of different specialties were selected. This review exclude theoretical articles, studies done on general public; studies conducted on other healthcare professionals; and also studies conducted on genetics of diseases. Results: Knowledge and practice regarding pharmacogenetics among doctors were poor despite good attitudes. Several studies revealed factors that influence integration of pharmacogenetics into patient care with interventional recommendations. Conclusion: There is a critical need for additional training on pharmacogenomics among doctors and also to incorporate it into medical school curriculum. Emphasis should be placed on how to accurately interpret and critically evaluate the use, and safety of pharmacogenetic testing.
|
| title |
A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors
|
| title_full |
A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors
|
| title_fullStr |
A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors
|
| title_full_unstemmed |
A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors
|
| title_short |
A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors
|
| title_sort |
systematic review of knowledge, attitude and practice towards pharmacogenomics among doctors
|