| _version_ |
1860797971654770688
|
| building |
INTELEK Repository
|
| collection |
Online Access
|
| collectionurl |
https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
|
| date |
2024-08-30 10:08:51
|
| format |
Restricted Document
|
| id |
15186
|
| institution |
UniSZA
|
| internalnotes |
1. Molan PC. Why honey is effective as a medicine 1. Its use in modern medicine. Bee World. 80 (2); 1999: 80-92. 2. Molan PC. Why honey is effective as a medicine 2. The scientific explanation of its effect. Bee World. 82 (1); 2001: 22-40. 3. Marshall C. The use of honey in wound care: A review article. British Journal of Podiatry. 5 (2); 2002: 47-49. 4. Al-Mamary M, Al-Meeri A and Al-Habori, M. Antioxidant Activities and Total Phenolics of Different Types of Honey. Nutrition Research. 22 (9); 2002; 1041-1047. 5. Barnes PJ, Shapiro SD and Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J. 22 (4); 2003; 672-688. 6. Daheshia M. Pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Clinical and Applied Immunology Reviews. 5; 2005:339-351. 7. MacNee W. Pathogenesis of Chronic Obstructive Pulmonary Disease. Proc Am Thorac Soc. 2(4); 2005: 258–266. doi:10.1513/pats.200504-045SR. Available from: URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713323/pdf/PR OCATS24258.pdf 8. Tuder RM and Petrache I. Pathogenesis of chronic obstructive pulmonary disease. J Clin Invest. 2012; 122(8): 2749– 2755.doi:10.1172/JCI60324. Available from: URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408733/pdf/JCI 60324.pdf 9. O’Donnell R, Breen D, Wilson S. and Djukanovic R. Inflammatory cells in the airways on COPD. Thorax. 61; 2006: 448-454. Available form: URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111192/pdf/448. pdf 10. MacNee W. Oxidants/Antioxidants and COPD. Chest. 117 (5 suppl 1); 2000: 303S-317S. 11. MacNee W. Treatment of stable COPD: antioxidants. Eur Respir Rev. 14 (94); 2005b: 12-22. 12. Rabe KF, Beghe B, Luppi, F and Fabbri LM. Update in Chronic Obstructive Pulmonary Disease 2006. Am J Respir Crit Care Med. 175 (12); 2007: 1222-1232. Available from: URL: http://www.atsjournals.org/doi/pdf/10.1164/rccm.200704-586UP 13. The Manchester University. Global strategy for the diagnosis, management and prevention of Chronic Obstructive Pulmonary Disease. Manchester, UK. Revised 2011. Available from: URL: http://www.goldcopd.org/uploads/users/files/GOLD_Report_201 1_Feb21.pdf 14. Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R, van Weel C, Zielinski J; Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007 15; 176(6):532-555. 15. Cesar-Neto JB, Duarte PM, Sallum EA, Barbieri D, Moreno H Jr and Nociti F H Jr. A comparative study on the effect of nicotine administration and cigarette smoke inhalation on bone healing around titanium implants. J Periodontol. 74 (10); 2003:1454-9. 16. Fox JC and Fitzgerald MF. Models of chronic obstructive pulmonary disease : a review of current status. Drug Discovery Today: Disease Models. 1 (3); 2004: 319-328. 17. Li QY, Huang SG, Wan HY, Wu HC, Zhou T, Li M, Deng WW. Effect of Smoking Cessation on Airway Inflammation of Rats with Chronic Bronchitis. Chin Med J (Engl). 120 (17); 2007: 1511-1516. 18. Mohamed M, Sulaiman SA, Jaafar H and Sirajudeen KNS. Effects of Malaysian Tualang honey on oxidative stress markers and testicular histology in rats exposed to cigarette smoke. 2nd International Conference on the Medicinal Use of Honey, Kelantan, Malaysia, Abstracts 32; 2010b: 13-15. 19. Cosio MG, Majo J and Cosio MG. Inflammation of the Airways and Lung Parenchyma in COPD: Role of T Cells. Chest. 121 (5 suppl); 2002:160S-165S. 20. Shapiro SD. The Macrophage in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 160 (5); 1999: S29-32. 21. MacNee W. Pathogenesis of chronic obstructive pulmonary disease. Clin Chest Med. 28 (3); 2007: 479-513. 22. Nagai T, Sakai M, Inoue R and Suzuki N. Anti-oxidative activities of some commercially honey, royal jelly and propolis. Food Chemistry. 75 (2); 2001: 237-240. 23. Sangrichan S and Wanson W. The antioxidant capacity of honey samples collected in the north part of Thailand in relationship with its total polyphenol. KMITL Sci J. 8 (2); 2008: 68-73. 24. Aljadi AM and Kamarudin MY. Evaluation of the phenolic contents and antioxidant capacities of two Malaysian floral honey. Food Chemistry. 85(4); 2002: 513-518. 25. Mohamed M, Sirajudeen KNS, Swamy M, Yaacob NS and Sulaiman SA. Studies on the Antioxidant Properties of Tualang Honey of Malaysia. Afr J Trad CAM. 7 (1); 2010a: 59-63. Available from: URL: http://www.ajol.info/index.php/ajtcam/article/view/57256/45649 26. Mesaik MA, Azim MK and Mohiuddin S. Honey modulates oxidative burst of professional phagocytes. Phytother Res. 22 (10); 2008: 1404-1408. 27. Ahmad A, Khan RA and Mesaik MA. Anti-inflammatory Effect of Natural Honey on Bovine Thrombin-induced Oxidative Burst in Phagocytes. Phytother Res. 23 (6); 2009: 801-808. 28. Tonks AJ, Cooper RA, Jones KP, Blair S, Parton J and Tonks A. Honey stimulates inflammatory cytokine production from monocytes. Cytokine. 21 (5); 2003: 242-7. 29. Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO and Paré PD. The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease. N Engl J Med. 350 (26); 2004: 2645-2653. 30. Abuharfeil N, Al-Oran R and Abo-Shehada M. The effect of bee honey on the proliferative activity of human B and Tlymphocytes and the activity of phagocytes. Food and Agricultural Immunology. 11(2); 1999: 169-177. 31. Chepulis LM. The Effects of Honey Compared with Sucrose and a Sugar-free Diet on Neutrophil Phagocytosis and Lymphocyte Numbers after Long-term Feeding in Rats. Journal of Complementary and Integrative Medicine. 4 (1); 2007: 1-7. 32. Al-Waili NS and Haq A. Effect of Honey on Antibody Production against Thymus-Dependent and Thymus-Independent Antigens in Primary and Secondary Immune Responses. J Med Food. 7 (4); 2004: 491-494 doi:10.1089/jmf.2004.7.491.
|
| originalfilename |
5663-01-FH02-FP-15-03089.pdf
|
| recordtype |
oai_dc
|
| resourceurl |
https://intelek.unisza.edu.my/intelek/pages/view.php?ref=15186
|
| spelling |
15186 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=15186 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf Adobe Acrobat Pro DC 20 Paper Capture Plug-in with ClearScan 6 1.7 2024-08-30 10:08:51 5663-01-FH02-FP-15-03089.pdf UniSZA Private Access The Effects of Honey on Inflammatory Cells in Cigarette Smoke Affected Lungs in Rats: A Preliminary Study Research Journal of Pharmacy and Technology Chronic Obstructive Pulmonary Disease (COPD) is a global significant health-delinquent. Inflammatory changes signify a clear indication in the early pathological changes of the airway in this disease and cigarette smoking is the most common risk factor. The ultimate goal in COPD is prevention. Recently, honey has been shown to have significant therapeutic possessions. The objective of this study was to evaluate the effect of honey on the inflammatory process in small airways of rats exposed to cigarette smoke. Twenty-three male rats between 8-9 weeks old were randomly divided into 3 groups. The first group was exposed daily to cigarette smoke alone using smoking apparatus. The second group was exposed to smoke and given oral honey at 1.2gm/kg body weight daily and the third group was assigned as control. The rats were sacrificed after four weeks of exposure and the lung tissues were processed accordingly. The sections were immunohistochemical stained with anti-CD68 and anti-CD8 for macrophages and CD8+ T lymphocytes counts. There was a significant reduction in the number of macrophages in the group exposed to cigarette smoke with honey compared to smoke exposure alone (z=-2.52, p= 0.012). However there was no significant reduction in the number of CD8+ T lymphocytes counts between the two groups (z=-0.40, p=0.690). Current study found honey has a prospective effect in reducing the macrophage recruitment in airways following inflammatory response due to cigarette smoke inhalations. 7 12 1382-1386 1. Molan PC. Why honey is effective as a medicine 1. Its use in modern medicine. Bee World. 80 (2); 1999: 80-92. 2. Molan PC. Why honey is effective as a medicine 2. The scientific explanation of its effect. Bee World. 82 (1); 2001: 22-40. 3. Marshall C. The use of honey in wound care: A review article. British Journal of Podiatry. 5 (2); 2002: 47-49. 4. Al-Mamary M, Al-Meeri A and Al-Habori, M. Antioxidant Activities and Total Phenolics of Different Types of Honey. Nutrition Research. 22 (9); 2002; 1041-1047. 5. Barnes PJ, Shapiro SD and Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J. 22 (4); 2003; 672-688. 6. Daheshia M. Pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Clinical and Applied Immunology Reviews. 5; 2005:339-351. 7. MacNee W. Pathogenesis of Chronic Obstructive Pulmonary Disease. Proc Am Thorac Soc. 2(4); 2005: 258–266. doi:10.1513/pats.200504-045SR. Available from: URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713323/pdf/PR OCATS24258.pdf 8. Tuder RM and Petrache I. Pathogenesis of chronic obstructive pulmonary disease. J Clin Invest. 2012; 122(8): 2749– 2755.doi:10.1172/JCI60324. Available from: URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408733/pdf/JCI 60324.pdf 9. O’Donnell R, Breen D, Wilson S. and Djukanovic R. Inflammatory cells in the airways on COPD. Thorax. 61; 2006: 448-454. Available form: URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111192/pdf/448. pdf 10. MacNee W. Oxidants/Antioxidants and COPD. Chest. 117 (5 suppl 1); 2000: 303S-317S. 11. MacNee W. Treatment of stable COPD: antioxidants. Eur Respir Rev. 14 (94); 2005b: 12-22. 12. Rabe KF, Beghe B, Luppi, F and Fabbri LM. Update in Chronic Obstructive Pulmonary Disease 2006. Am J Respir Crit Care Med. 175 (12); 2007: 1222-1232. Available from: URL: http://www.atsjournals.org/doi/pdf/10.1164/rccm.200704-586UP 13. The Manchester University. Global strategy for the diagnosis, management and prevention of Chronic Obstructive Pulmonary Disease. Manchester, UK. Revised 2011. Available from: URL: http://www.goldcopd.org/uploads/users/files/GOLD_Report_201 1_Feb21.pdf 14. Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R, van Weel C, Zielinski J; Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007 15; 176(6):532-555. 15. Cesar-Neto JB, Duarte PM, Sallum EA, Barbieri D, Moreno H Jr and Nociti F H Jr. A comparative study on the effect of nicotine administration and cigarette smoke inhalation on bone healing around titanium implants. J Periodontol. 74 (10); 2003:1454-9. 16. Fox JC and Fitzgerald MF. Models of chronic obstructive pulmonary disease : a review of current status. Drug Discovery Today: Disease Models. 1 (3); 2004: 319-328. 17. Li QY, Huang SG, Wan HY, Wu HC, Zhou T, Li M, Deng WW. Effect of Smoking Cessation on Airway Inflammation of Rats with Chronic Bronchitis. Chin Med J (Engl). 120 (17); 2007: 1511-1516. 18. Mohamed M, Sulaiman SA, Jaafar H and Sirajudeen KNS. Effects of Malaysian Tualang honey on oxidative stress markers and testicular histology in rats exposed to cigarette smoke. 2nd International Conference on the Medicinal Use of Honey, Kelantan, Malaysia, Abstracts 32; 2010b: 13-15. 19. Cosio MG, Majo J and Cosio MG. Inflammation of the Airways and Lung Parenchyma in COPD: Role of T Cells. Chest. 121 (5 suppl); 2002:160S-165S. 20. Shapiro SD. The Macrophage in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 160 (5); 1999: S29-32. 21. MacNee W. Pathogenesis of chronic obstructive pulmonary disease. Clin Chest Med. 28 (3); 2007: 479-513. 22. Nagai T, Sakai M, Inoue R and Suzuki N. Anti-oxidative activities of some commercially honey, royal jelly and propolis. Food Chemistry. 75 (2); 2001: 237-240. 23. Sangrichan S and Wanson W. The antioxidant capacity of honey samples collected in the north part of Thailand in relationship with its total polyphenol. KMITL Sci J. 8 (2); 2008: 68-73. 24. Aljadi AM and Kamarudin MY. Evaluation of the phenolic contents and antioxidant capacities of two Malaysian floral honey. Food Chemistry. 85(4); 2002: 513-518. 25. Mohamed M, Sirajudeen KNS, Swamy M, Yaacob NS and Sulaiman SA. Studies on the Antioxidant Properties of Tualang Honey of Malaysia. Afr J Trad CAM. 7 (1); 2010a: 59-63. Available from: URL: http://www.ajol.info/index.php/ajtcam/article/view/57256/45649 26. Mesaik MA, Azim MK and Mohiuddin S. Honey modulates oxidative burst of professional phagocytes. Phytother Res. 22 (10); 2008: 1404-1408. 27. Ahmad A, Khan RA and Mesaik MA. Anti-inflammatory Effect of Natural Honey on Bovine Thrombin-induced Oxidative Burst in Phagocytes. Phytother Res. 23 (6); 2009: 801-808. 28. Tonks AJ, Cooper RA, Jones KP, Blair S, Parton J and Tonks A. Honey stimulates inflammatory cytokine production from monocytes. Cytokine. 21 (5); 2003: 242-7. 29. Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO and Paré PD. The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease. N Engl J Med. 350 (26); 2004: 2645-2653. 30. Abuharfeil N, Al-Oran R and Abo-Shehada M. The effect of bee honey on the proliferative activity of human B and Tlymphocytes and the activity of phagocytes. Food and Agricultural Immunology. 11(2); 1999: 169-177. 31. Chepulis LM. The Effects of Honey Compared with Sucrose and a Sugar-free Diet on Neutrophil Phagocytosis and Lymphocyte Numbers after Long-term Feeding in Rats. Journal of Complementary and Integrative Medicine. 4 (1); 2007: 1-7. 32. Al-Waili NS and Haq A. Effect of Honey on Antibody Production against Thymus-Dependent and Thymus-Independent Antigens in Primary and Secondary Immune Responses. J Med Food. 7 (4); 2004: 491-494 doi:10.1089/jmf.2004.7.491.
|
| spellingShingle |
The Effects of Honey on Inflammatory Cells in Cigarette Smoke Affected Lungs in Rats: A Preliminary Study
|
| summary |
Chronic Obstructive Pulmonary Disease (COPD) is a global significant health-delinquent. Inflammatory changes signify a clear indication in the early pathological changes of the airway in this disease and cigarette smoking is the most common risk factor. The ultimate goal in COPD is prevention. Recently, honey has been shown to have significant therapeutic possessions. The objective of this study was to evaluate the effect of honey on the inflammatory process in small airways of rats exposed to cigarette smoke. Twenty-three male rats between 8-9 weeks old were randomly divided into 3 groups. The first group was exposed daily to cigarette smoke alone using smoking apparatus. The second group was exposed to smoke and given oral honey at 1.2gm/kg body weight daily and the third group was assigned as control. The rats were sacrificed after four weeks of exposure and the lung tissues were processed accordingly. The sections were immunohistochemical stained with anti-CD68 and anti-CD8 for macrophages and CD8+ T lymphocytes counts. There was a significant reduction in the number of macrophages in the group exposed to cigarette smoke with honey compared to smoke exposure alone (z=-2.52, p= 0.012). However there was no significant reduction in the number of CD8+ T lymphocytes counts between the two groups (z=-0.40, p=0.690). Current study found honey has a prospective effect in reducing the macrophage recruitment in airways following inflammatory response due to cigarette smoke inhalations.
|
| title |
The Effects of Honey on Inflammatory Cells in Cigarette Smoke Affected Lungs in Rats: A Preliminary Study
|
| title_full |
The Effects of Honey on Inflammatory Cells in Cigarette Smoke Affected Lungs in Rats: A Preliminary Study
|
| title_fullStr |
The Effects of Honey on Inflammatory Cells in Cigarette Smoke Affected Lungs in Rats: A Preliminary Study
|
| title_full_unstemmed |
The Effects of Honey on Inflammatory Cells in Cigarette Smoke Affected Lungs in Rats: A Preliminary Study
|
| title_short |
The Effects of Honey on Inflammatory Cells in Cigarette Smoke Affected Lungs in Rats: A Preliminary Study
|
| title_sort |
effects of honey on inflammatory cells in cigarette smoke affected lungs in rats: a preliminary study
|