A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc

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caption : A new abietene diterpene, kaempfolienol (5S,6S,7S,9S,10S,11R,13S-abiet-8(14)-enepenta-6,7,9,11,13-ol, 1), was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide, boesenboxide, zeylenol, 2′-hydrox
collection Online Access
collectionurl https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
date 2024-08-26 15:04:47
format Restricted Document
id 14509
institution UniSZA
originalfilename 2167-01-FH02-FPBSM-14-00511.pdf
person Sook Wah Tang
recordtype oai_dc
resourceurl https://intelek.unisza.edu.my/intelek/pages/view.php?ref=14509
spelling 14509 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=14509 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf Adobe Acrobat Pro DC 20 Paper Capture Plug-in with ClearScan 12 1.6 9 11 7 Sook Wah Tang 2024-08-26 15:04:47 : A new abietene diterpene, kaempfolienol (5S,6S,7S,9S,10S,11R,13S-abiet-8(14)-enepenta-6,7,9,11,13-ol, 1), was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide, boesenboxide, zeylenol, 2′-hydrox : A new abietene diterpene kaempfolienol (5S 6S 7S 9S 10S 11R 13S-abiet-8(14)-enepenta-6 13-ol 1) was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide boesenboxide zeylenol 2′-hydrox 2167-01-FH02-FPBSM-14-00511.pdf UniSZA Private Access A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc Molecules A new abietene diterpene, kaempfolienol (5S,6S,7S,9S,10S,11R,13S-abiet-8(14)- enepenta-6,7,9,11,13-ol, 1), was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide, boesenboxide, zeylenol, 2′-hydroxy-4,4′,6′-trimethoxychalcone, (24S)-24-methyl-5α-lanosta-9(11),25-dien-3β-ol, β-sitosterol and β-sitosterol-3-O-β-D-glucopyranoside. The structures of all compounds were elucidated on the basis of mass spectroscopic and NMR data. Zeylenol (2), the major constituent of the plant, was derivatized into diacetate, triacetate and epoxide derivatives through standard organic reactions. The cytotoxic activity of compounds 1, 2 and the zeylenol derivatives was evaluated against the HL-60, MCF-7, HT-29 and HeLa cell lines. 3018-3028
spellingShingle A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc
subject 9
11
7
: A new abietene diterpene
kaempfolienol (5S
6S
7S
9S
10S
11R
13S-abiet-8(14)-enepenta-6
13-ol
1)
was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide
boesenboxide
zeylenol
2′-hydrox
summary A new abietene diterpene, kaempfolienol (5S,6S,7S,9S,10S,11R,13S-abiet-8(14)- enepenta-6,7,9,11,13-ol, 1), was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide, boesenboxide, zeylenol, 2′-hydroxy-4,4′,6′-trimethoxychalcone, (24S)-24-methyl-5α-lanosta-9(11),25-dien-3β-ol, β-sitosterol and β-sitosterol-3-O-β-D-glucopyranoside. The structures of all compounds were elucidated on the basis of mass spectroscopic and NMR data. Zeylenol (2), the major constituent of the plant, was derivatized into diacetate, triacetate and epoxide derivatives through standard organic reactions. The cytotoxic activity of compounds 1, 2 and the zeylenol derivatives was evaluated against the HL-60, MCF-7, HT-29 and HeLa cell lines.
title A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc
title_full A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc
title_fullStr A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc
title_full_unstemmed A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc
title_short A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc
title_sort new abietene diterpene and other constituents from kaempferia angustifolia rosc