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INTELEK Repository
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Online Access
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https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
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2024-08-27 16:26:41
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Restricted Document
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13087
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UniSZA
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1. Islam MZ, Rahman MF, Mossaddek ASM, Rozario RJ, Iftekhar AFMH, Akhter S, Jahan I, Helali AM, Dali WPEW, Ismail S, Rahman NIA, Haque M. Bangladeshi Interns' Knowledge of Pharmacology and Therapeutics for Prescribing. J App Pharm Sci, 2014; 4 (04): 043-051. 2. Salam A, Haque M, Islam MZ, Rahman NIA, Helali AM, Muda TFMBT, Yousuf R, Yesmin F, Rahman Z, Alattraqchi AG. Addressing Rational Prescribers through the Pharmacology and Therapeutics Course Work of MBBS Syllabus in Bangladesh. Int Res J Pharm, 2013; 4 (7): 60- 63. 3. Mahmood KT, Amin F, Tahir M, Haq IU. Pharmacovigilance – A Need for Best Patient Care in Pakistan. A review. J Pharm Sci Res, 2011; 3(11): 1566-1584. 4. Kingsmore SF, Lindquist IE, Mudge J, Gessler DD, Beavis WD. Genome-wide association studies: progress and potential for drug discovery and development. Nat Rev Drug Discov, 2008; 7(3): 221-230. 5. Jeetu G, Anusha G. Pharmacovigilance: a worldwide master key for drug safety monitoring. J Young Pharm, 2010; 2(3): 315-320. 6. Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA, 1998; 279(15), 1200-1205. 7. Rabbur RSM, Emmerton L. An introduction to adverse drug reaction reporting systems in different countries. Int J Pharm Pract, 2005; 13(1): 91–100. 8. Salam A, Yousuf R, Islam MZ, Yesmin F, Helali AM, Alattraqchi AG, Rao UM, Haque M. Professionalism of future medical professionals in Universiti Sultan Zainal Abidin, Malaysia. Bangladesh Journal of Pharmacology, 2013; 8(2):124-30. 9. Salam A, Haque M, Islam MZ, Helali AM, Yousuf R, Yesmin F, Alattraqchi AG, Rao UM. Comparative study of professionalism of future medical professionals among three private medical colleges of Bangladesh. Asian Journal of Pharmaceutical and Clinical Research. 2013; 6(3): 170-179. 10. Salam AB, Haque MA, Helali AM, Islam MZ, Mohsena M, Rahman Z, Yesmin F, Rahman N, Alattaraqchi AG, Yousuf R. Comparative study on professionalism of forthcoming medical doctors between two private medical colleges in Savar, Bangladesh. Int J Pharm Pharm Sci. 2013;5(Suppl 3):659-65. 11. Islam MZ, Salam A, Helali AM, Rahman Z, Dali WP, Ismail S, Rahman NI, Haque M. Comparative study of professionalism of future medical doctors between Malaysia and Bangladesh. J App Pharm Sci, 2014; 4(04):066-71. 12. Helali AM, Iqbal M, Islam M, Haque M. The Evolving Role of Pharmacovigilance and Drug Safety: The Way Forward for Bangladesh. International Journal of Pharmaceutical Research. 2014; 6(4):31-7. 13. Salleh MZ, Teh LK, Lee LS, Ismet RI, Patowary A, Joshi K, Pasha A, Ahmed AZ, Janor RM, Hamzah AS, Adam A. Systematic pharmacogenomics analysis of a Malay whole genome: proof of concept for personalized medicine. PloS one, 2013; 8(8): e71554. 14. Yau A, Husain R, Haque M. A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors. Int J Pharm Res, 2015a; 7(1): 9-16. 15. Yau A, Aziz ABA, Haque M. Knowledge, Attitude, and Practice Concerning Pharmacogenomics among Pharmacists A Systematic Review. J Young Pharm, 2015b; 7(3): 145–154. 16. Hadi MA, Hughes J. Broader perspective needed on the PharmD degree in Pakistan. Am J Pharm Edu, 2009 ;73(6): 114. 17. Huston SA, Zdanowicz MM, Fetterman JW. Pharmacogenomics in advanced pharmacy practice experiences. Am J Pharm Educ, 2010; 2 (4): 196–203. 18. Bannur Z, Bahaman S, Salleh MZ, Teh LK. Pharmacogenomics Based Practice in Malaysia : The Attitude, Knowledge and Adoption by the Healthcare Demographics of Respondents. IMJM, 2014; 13(1): 41-50. 19. Kun CK. Policies and Policing in Malaysia. CJI Archives, 1996; 12 (2): Available from: http://www.cjimagazine.com/archives/cji0255.ht ml?id=454 [Access on 20-12-2015] 20. Malaysian Study Council. Malaysian Geography. Available from: http://malaysianstudy.wix.com/malaysianstudy#!land--people/czf3 [Access on 20-12-2015] 21. Ministry of Health (MOH). Country Health Plan. 10th Malaysian Plan 2011-2015. 1 Care for 1 Malaysia. Kementerian Kesihatan Malaysia. Bahagian Perancangan Dan Pembangunan. Aras 6 – 9 Blok E 6 Kompleks E. Pusat Pentadbiran Kerajaan Persekutuan. 62198 Putrajaya. Malaysia. 2015. Available from: http://www.moh.gov.my/images/gallery/Report/ Country_health.pdf [Access on 20-12-2015] 22. Cordell HJ. Sample size requirements to control for stochastic variation in magnitude and location of allele-sharing linkage statistics in affected sibling pairs. Ann Hum Genet, 2001; 65: 491-502. 23. Charan J, Biswas T. How to Calculate Sample Size for Different Study Designs in Medical Research? Indian J Psychol Med, 2013;35(2):121-126. 24. Jones S, Carley S, Harrison M. An introduction to power and sample size estimation. Emerg Med J, 2003; 20(5): 453-458. 25. Yau A, Husain R, Aziz AA, Johari MKBZ, Rahman AFB, Elkalmi RM, Jamilu Y, Haque M. Psychometric Properties of Knowledge, Attitude, and Practice on Pharmacogenovigilance in Drug Safety Questionnaire in Medicine and Pharmacy Students: based on Exploratory Factor Analysis. J App Pharm Sci, 2015; 5 (11): 015-022. 26. Yau A, Haque M. Pharmacogenomics: Knowledge, Attitude and Practice among Future Doctors and Pharmacists – A Pilot Study. J App Pharm Sci, 2016 (In Press) 27. Elkalmi RM, Hassali MA, Ibrahim MIM, Widodo RT, Efan QMA, Hadi MA. Pharmacy students’ knowledge and perceptions about pharmacovigilance in Malaysian public universities. Am J Pharm Educ, 2011; 75(5): 96. 28. Sivadasan S, Yuong NY, Chyi NW, Lau A, Ching ALS, Ali AN, Veerasamy R, Marimuthu K, Arumugam S. Knowledge and Perception Towards Pharmacovigilance and Adverse Drug Reaction Reporting Among Medicine and Pharmacy Students. World J Pharm Pharm Sci, 2014; 3(3), 1652-1676. 29. Benzeroual KE, Shah B, Shinde S. Pharmacogenomics: assessing educational exposure, confidence in knowledge and training elements of pharmacists. Per Med, 2012; 9(4), 387-393. 30. de Denus S, Letarte N, Hurlimann T, Lambert JP, Lavoie A, Robb L, Sheehan NL, Turgeon J, Vadnais B. An evaluation of pharmacists’ expectations towards pharmacogenomics. Pharmacogenomics, 2013; 14(2): 165-175. 31. Latif DA, McKay AB. Pharmacogenetics and Pharmacogenomics Instruction in Colleges and Schools of Pharmacy in the United States. Am J Pharm Educ, 2005; 69(2): Article 23. 32. Mccullough KB, Formea CM, Berg KD, Burzynski JA, Cunningham JL, Ou NN, Rudis MI, Stollings JL, Nicholson WT. Assessment of the pharmacogenomics educational needs of pharmacists. Am J Pharm Educ, 2011; 3 (11): 1566- 154. 33. Tuteja S, Haynes K, Zayac C, Sprague JE, Bernhardt B, Pyeritz R. Community pharmacists’ attitudes towards clinical utility and ethical implications of pharmacogenetic testing. Per Med, 2013; 10(8). 34. Roederer MW, Van Riper M, Valgus J, Knafl G, McLeod H. Knowledge, attitudes and education of pharmacists regarding pharmacogenetic testing. Per Med, 2012; 9(1), 19–27. 35. O’Donnell PH, Bush A, Spitz J, Danahey K, Saner D, Das S, Cox NJ, Ratain MJ. The 1200 Patients Project: Creating A New Medical Model System for Clinical Implementation of Pharmacogenomics. Clin Pharmacol Ther, 2012;92(4):446-449. doi:10.1038/clpt.2012.117. 36. Dressler LG, Deal AM, Patel J, Markey J, Van Riper M, McLeod HL. Cancer Pharmacogenomics, Adoption by Oncologists and Patient Benefit. Per Med, 2014; 11(2): 143-153. 37. Bernhardt BA, Zayac C, Gordon ES, Wawak L, Pyeritz RE, Gollust SE. Incorporating direct-toconsumer genomic information into patient care: attitudes and experiences of primary care physicians. Per Med, 2012; 9(7), 683-692. 38. Klitzman R, Chung W, Marder K, Shanmugham A, Chin LJ, Stark M, Leu CS, Appelbaum PS. Attitudes and Practices Among Internists Concerning Genetic Testing. J Genet Couns, 2013; 22(1), 90-100. 39. Johansen Taber KA, Dickinson BD. Pharmacogenomic knowledge gaps and educational resource needs among physicians in selected specialties. Pharmgenomics Pers Med, 2014; 7: 145- 162. 40. Baars MJ, Henneman L, Ten Kate LP. Deficiency of knowledge of genetics and genetic tests among general practitioners, gynecologists, and pediatricians: A global problem. Genet Med, 2005;7(9):605-610. 41. Rogausch A, Prause D, Schallenberg A, Brockmöller J. Himmel W. Patients’ and physicians' perspectives on pharmacogenetic testing. Pharmacogenomics, 2006; 7(1): 49-59. 42. Ohata T, Tsuchiya A, Watanabe M, Sumida T, Takada F. Physicians’ opinion for “new” genetic testing in Japan. J Hum Genet, 2009; 54(4): 203-208. 43. Zembles T. An in-service program on pharmacogenetics to individualize drug therapy. Am J Pharm Educ, 2010; 74(1): 10. 44. Newton R, Lithgow J, Po ALW, Bennett C, Farndon P. How will pharmacogenetics impact on pharmacy practice? Pharmacists’ views and educational priorities. The NHS National Genetics Education and Development Centre. Royal Pharmaceutical Society of Great Britain. Morris House, c/o Birmingham, Women’s Hospital Edgbaston, Birmingham B15 2TG. 2007. Available from: http://www.geneticseducation.nhs.uk/downloads /0067Pharmacogenetic_impact_report_Nov_20 07.pdf [Access on 20-12-2015] 45. McMahon T, Tucci J. The perceptions of pharmacists in Victoria, Australia on pharmacogenetics and its implications. Pharm Pract (Granada), 2011; 9(3): 141–7. 46. Filiptsova OV, Kobets MN, Kobets YN. Some aspects of genetics and pharmacogenetics understanding by pharmacy students in Ukraine. Egypt J Med Hum Genet, 2015; 16(1): 61-66. 47. Rajiah K, Maharajan MK, Nair S. Pharmacy students’ knowledge and perceptions about adverse drug reactions reporting and pharmacovigilance. Saudi Pharm J, 2015 (In Press) Available from: http://www.sciencedirect.com/science/article/pii/ S1319016415000845 [Access on 21-12-2015]
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7397-01-FH02-FP-16-05999.pdf
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oai_dc
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13087 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=13087 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf Adobe Acrobat Pro DC 20 Paper Capture Plug-in with ClearScan 16 1.6 Compaq 2024-08-27 16:26:41 7397-01-FH02-FP-16-05999.pdf UniSZA Private Access Pharmacogenovigilance in Drug Safety: Knowledge, Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia International Journal of Pharmaceutical Research The need for adoption of pharmacogenomics and pharmacovigilance into practice among healthcare professionals has been increasing as this provides greener future to individualized medicine and drug safety. This study aimed to assess the knowledge, attitude and practice of final-year Medicine and Pharmacy students towards Pharmacogenomics, and pharmacovigilance in drug safety at some public and private universities Peninsular Malaysia. A cross-sectional study was conducted using a self-administered questionnaire (Cronbach's alpha coefficient 0.822) among 465 participants, yielding a response rate of 380 (82.1%) over the period of the study. The analysis of the continue variables was done using the student t-test and one-way ANOVA. The associations between categorical variables were analyzed using the Chi-square test. The independent t-test revealed that, the mean knowledge and attitude scores among final-year pharmacy students were 89.20±8.86% and 73.7±6.59%, and that of final-year medical students were 84.95±13.2% and 69.7±7.74% respectively, with a statistically significant difference (p-value<0.001 at 95% CI). A low level of practice was observed with a statistically significant difference between a pharmacy and medical students (P<0.05). Findings revealed that the questionnaire was a valid and reliable instrument that could be used for the same purpose under the same condition. The majority demonstrated good knowledge and attitude towards pharmacogenovigilance in drug safety, but with a low level of practice. These findings show the readiness of the participated final-year medical and pharmacy students towards the pharmacogenomic based challenges and integration of pharmacogenomics into practice. 8 1 57-71 1. Islam MZ, Rahman MF, Mossaddek ASM, Rozario RJ, Iftekhar AFMH, Akhter S, Jahan I, Helali AM, Dali WPEW, Ismail S, Rahman NIA, Haque M. Bangladeshi Interns' Knowledge of Pharmacology and Therapeutics for Prescribing. J App Pharm Sci, 2014; 4 (04): 043-051. 2. Salam A, Haque M, Islam MZ, Rahman NIA, Helali AM, Muda TFMBT, Yousuf R, Yesmin F, Rahman Z, Alattraqchi AG. Addressing Rational Prescribers through the Pharmacology and Therapeutics Course Work of MBBS Syllabus in Bangladesh. Int Res J Pharm, 2013; 4 (7): 60- 63. 3. Mahmood KT, Amin F, Tahir M, Haq IU. Pharmacovigilance – A Need for Best Patient Care in Pakistan. A review. J Pharm Sci Res, 2011; 3(11): 1566-1584. 4. Kingsmore SF, Lindquist IE, Mudge J, Gessler DD, Beavis WD. Genome-wide association studies: progress and potential for drug discovery and development. Nat Rev Drug Discov, 2008; 7(3): 221-230. 5. Jeetu G, Anusha G. Pharmacovigilance: a worldwide master key for drug safety monitoring. J Young Pharm, 2010; 2(3): 315-320. 6. Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA, 1998; 279(15), 1200-1205. 7. Rabbur RSM, Emmerton L. An introduction to adverse drug reaction reporting systems in different countries. Int J Pharm Pract, 2005; 13(1): 91–100. 8. Salam A, Yousuf R, Islam MZ, Yesmin F, Helali AM, Alattraqchi AG, Rao UM, Haque M. Professionalism of future medical professionals in Universiti Sultan Zainal Abidin, Malaysia. Bangladesh Journal of Pharmacology, 2013; 8(2):124-30. 9. Salam A, Haque M, Islam MZ, Helali AM, Yousuf R, Yesmin F, Alattraqchi AG, Rao UM. Comparative study of professionalism of future medical professionals among three private medical colleges of Bangladesh. Asian Journal of Pharmaceutical and Clinical Research. 2013; 6(3): 170-179. 10. Salam AB, Haque MA, Helali AM, Islam MZ, Mohsena M, Rahman Z, Yesmin F, Rahman N, Alattaraqchi AG, Yousuf R. Comparative study on professionalism of forthcoming medical doctors between two private medical colleges in Savar, Bangladesh. Int J Pharm Pharm Sci. 2013;5(Suppl 3):659-65. 11. Islam MZ, Salam A, Helali AM, Rahman Z, Dali WP, Ismail S, Rahman NI, Haque M. Comparative study of professionalism of future medical doctors between Malaysia and Bangladesh. J App Pharm Sci, 2014; 4(04):066-71. 12. Helali AM, Iqbal M, Islam M, Haque M. The Evolving Role of Pharmacovigilance and Drug Safety: The Way Forward for Bangladesh. International Journal of Pharmaceutical Research. 2014; 6(4):31-7. 13. Salleh MZ, Teh LK, Lee LS, Ismet RI, Patowary A, Joshi K, Pasha A, Ahmed AZ, Janor RM, Hamzah AS, Adam A. Systematic pharmacogenomics analysis of a Malay whole genome: proof of concept for personalized medicine. PloS one, 2013; 8(8): e71554. 14. Yau A, Husain R, Haque M. A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors. Int J Pharm Res, 2015a; 7(1): 9-16. 15. Yau A, Aziz ABA, Haque M. Knowledge, Attitude, and Practice Concerning Pharmacogenomics among Pharmacists A Systematic Review. J Young Pharm, 2015b; 7(3): 145–154. 16. Hadi MA, Hughes J. Broader perspective needed on the PharmD degree in Pakistan. Am J Pharm Edu, 2009 ;73(6): 114. 17. Huston SA, Zdanowicz MM, Fetterman JW. Pharmacogenomics in advanced pharmacy practice experiences. Am J Pharm Educ, 2010; 2 (4): 196–203. 18. Bannur Z, Bahaman S, Salleh MZ, Teh LK. Pharmacogenomics Based Practice in Malaysia : The Attitude, Knowledge and Adoption by the Healthcare Demographics of Respondents. IMJM, 2014; 13(1): 41-50. 19. Kun CK. Policies and Policing in Malaysia. CJI Archives, 1996; 12 (2): Available from: http://www.cjimagazine.com/archives/cji0255.ht ml?id=454 [Access on 20-12-2015] 20. Malaysian Study Council. Malaysian Geography. Available from: http://malaysianstudy.wix.com/malaysianstudy#!land--people/czf3 [Access on 20-12-2015] 21. Ministry of Health (MOH). Country Health Plan. 10th Malaysian Plan 2011-2015. 1 Care for 1 Malaysia. Kementerian Kesihatan Malaysia. Bahagian Perancangan Dan Pembangunan. Aras 6 – 9 Blok E 6 Kompleks E. Pusat Pentadbiran Kerajaan Persekutuan. 62198 Putrajaya. Malaysia. 2015. Available from: http://www.moh.gov.my/images/gallery/Report/ Country_health.pdf [Access on 20-12-2015] 22. Cordell HJ. Sample size requirements to control for stochastic variation in magnitude and location of allele-sharing linkage statistics in affected sibling pairs. Ann Hum Genet, 2001; 65: 491-502. 23. Charan J, Biswas T. How to Calculate Sample Size for Different Study Designs in Medical Research? Indian J Psychol Med, 2013;35(2):121-126. 24. Jones S, Carley S, Harrison M. An introduction to power and sample size estimation. Emerg Med J, 2003; 20(5): 453-458. 25. Yau A, Husain R, Aziz AA, Johari MKBZ, Rahman AFB, Elkalmi RM, Jamilu Y, Haque M. Psychometric Properties of Knowledge, Attitude, and Practice on Pharmacogenovigilance in Drug Safety Questionnaire in Medicine and Pharmacy Students: based on Exploratory Factor Analysis. J App Pharm Sci, 2015; 5 (11): 015-022. 26. Yau A, Haque M. Pharmacogenomics: Knowledge, Attitude and Practice among Future Doctors and Pharmacists – A Pilot Study. J App Pharm Sci, 2016 (In Press) 27. Elkalmi RM, Hassali MA, Ibrahim MIM, Widodo RT, Efan QMA, Hadi MA. Pharmacy students’ knowledge and perceptions about pharmacovigilance in Malaysian public universities. Am J Pharm Educ, 2011; 75(5): 96. 28. Sivadasan S, Yuong NY, Chyi NW, Lau A, Ching ALS, Ali AN, Veerasamy R, Marimuthu K, Arumugam S. Knowledge and Perception Towards Pharmacovigilance and Adverse Drug Reaction Reporting Among Medicine and Pharmacy Students. World J Pharm Pharm Sci, 2014; 3(3), 1652-1676. 29. Benzeroual KE, Shah B, Shinde S. Pharmacogenomics: assessing educational exposure, confidence in knowledge and training elements of pharmacists. Per Med, 2012; 9(4), 387-393. 30. de Denus S, Letarte N, Hurlimann T, Lambert JP, Lavoie A, Robb L, Sheehan NL, Turgeon J, Vadnais B. An evaluation of pharmacists’ expectations towards pharmacogenomics. Pharmacogenomics, 2013; 14(2): 165-175. 31. Latif DA, McKay AB. Pharmacogenetics and Pharmacogenomics Instruction in Colleges and Schools of Pharmacy in the United States. Am J Pharm Educ, 2005; 69(2): Article 23. 32. Mccullough KB, Formea CM, Berg KD, Burzynski JA, Cunningham JL, Ou NN, Rudis MI, Stollings JL, Nicholson WT. Assessment of the pharmacogenomics educational needs of pharmacists. Am J Pharm Educ, 2011; 3 (11): 1566- 154. 33. Tuteja S, Haynes K, Zayac C, Sprague JE, Bernhardt B, Pyeritz R. Community pharmacists’ attitudes towards clinical utility and ethical implications of pharmacogenetic testing. Per Med, 2013; 10(8). 34. Roederer MW, Van Riper M, Valgus J, Knafl G, McLeod H. Knowledge, attitudes and education of pharmacists regarding pharmacogenetic testing. Per Med, 2012; 9(1), 19–27. 35. O’Donnell PH, Bush A, Spitz J, Danahey K, Saner D, Das S, Cox NJ, Ratain MJ. The 1200 Patients Project: Creating A New Medical Model System for Clinical Implementation of Pharmacogenomics. Clin Pharmacol Ther, 2012;92(4):446-449. doi:10.1038/clpt.2012.117. 36. Dressler LG, Deal AM, Patel J, Markey J, Van Riper M, McLeod HL. Cancer Pharmacogenomics, Adoption by Oncologists and Patient Benefit. Per Med, 2014; 11(2): 143-153. 37. Bernhardt BA, Zayac C, Gordon ES, Wawak L, Pyeritz RE, Gollust SE. Incorporating direct-toconsumer genomic information into patient care: attitudes and experiences of primary care physicians. Per Med, 2012; 9(7), 683-692. 38. Klitzman R, Chung W, Marder K, Shanmugham A, Chin LJ, Stark M, Leu CS, Appelbaum PS. Attitudes and Practices Among Internists Concerning Genetic Testing. J Genet Couns, 2013; 22(1), 90-100. 39. Johansen Taber KA, Dickinson BD. Pharmacogenomic knowledge gaps and educational resource needs among physicians in selected specialties. Pharmgenomics Pers Med, 2014; 7: 145- 162. 40. Baars MJ, Henneman L, Ten Kate LP. Deficiency of knowledge of genetics and genetic tests among general practitioners, gynecologists, and pediatricians: A global problem. Genet Med, 2005;7(9):605-610. 41. Rogausch A, Prause D, Schallenberg A, Brockmöller J. Himmel W. Patients’ and physicians' perspectives on pharmacogenetic testing. Pharmacogenomics, 2006; 7(1): 49-59. 42. Ohata T, Tsuchiya A, Watanabe M, Sumida T, Takada F. Physicians’ opinion for “new” genetic testing in Japan. J Hum Genet, 2009; 54(4): 203-208. 43. Zembles T. An in-service program on pharmacogenetics to individualize drug therapy. Am J Pharm Educ, 2010; 74(1): 10. 44. Newton R, Lithgow J, Po ALW, Bennett C, Farndon P. How will pharmacogenetics impact on pharmacy practice? Pharmacists’ views and educational priorities. The NHS National Genetics Education and Development Centre. Royal Pharmaceutical Society of Great Britain. Morris House, c/o Birmingham, Women’s Hospital Edgbaston, Birmingham B15 2TG. 2007. Available from: http://www.geneticseducation.nhs.uk/downloads /0067Pharmacogenetic_impact_report_Nov_20 07.pdf [Access on 20-12-2015] 45. McMahon T, Tucci J. The perceptions of pharmacists in Victoria, Australia on pharmacogenetics and its implications. Pharm Pract (Granada), 2011; 9(3): 141–7. 46. Filiptsova OV, Kobets MN, Kobets YN. Some aspects of genetics and pharmacogenetics understanding by pharmacy students in Ukraine. Egypt J Med Hum Genet, 2015; 16(1): 61-66. 47. Rajiah K, Maharajan MK, Nair S. Pharmacy students’ knowledge and perceptions about adverse drug reactions reporting and pharmacovigilance. Saudi Pharm J, 2015 (In Press) Available from: http://www.sciencedirect.com/science/article/pii/ S1319016415000845 [Access on 21-12-2015]
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| spellingShingle |
Pharmacogenovigilance in Drug Safety: Knowledge, Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia
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| summary |
The need for adoption of pharmacogenomics and pharmacovigilance into practice among healthcare professionals has been increasing as this provides greener future to individualized medicine and drug safety. This study aimed to assess the knowledge, attitude and practice of final-year Medicine and Pharmacy students towards Pharmacogenomics, and pharmacovigilance in drug safety at some public and private universities Peninsular Malaysia. A cross-sectional study was conducted using a self-administered questionnaire (Cronbach's alpha coefficient 0.822) among 465 participants, yielding a response rate of 380 (82.1%) over the period of the study. The analysis of the continue variables was done using the student t-test and one-way ANOVA. The associations between categorical variables were analyzed using the Chi-square test. The independent t-test revealed that, the mean knowledge and attitude scores among final-year pharmacy students were 89.20±8.86% and 73.7±6.59%, and that of final-year medical students were 84.95±13.2% and 69.7±7.74% respectively, with a statistically significant difference (p-value<0.001 at 95% CI). A low level of practice was observed with a statistically significant difference between a pharmacy and medical students (P<0.05). Findings revealed that the questionnaire was a valid and reliable instrument that could be used for the same purpose under the same condition. The majority demonstrated good knowledge and attitude towards pharmacogenovigilance in drug safety, but with a low level of practice. These findings show the readiness of the participated final-year medical and pharmacy students towards the pharmacogenomic based challenges and integration of pharmacogenomics into practice.
|
| title |
Pharmacogenovigilance in Drug Safety: Knowledge, Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia
|
| title_full |
Pharmacogenovigilance in Drug Safety: Knowledge, Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia
|
| title_fullStr |
Pharmacogenovigilance in Drug Safety: Knowledge, Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia
|
| title_full_unstemmed |
Pharmacogenovigilance in Drug Safety: Knowledge, Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia
|
| title_short |
Pharmacogenovigilance in Drug Safety: Knowledge, Attitudes and Practice Among Final-Year Medical and Pharmacy Students in Peninsular Malaysia
|
| title_sort |
pharmacogenovigilance in drug safety: knowledge, attitudes and practice among final-year medical and pharmacy students in peninsular malaysia
|