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1860797479120797696
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INTELEK Repository
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Online Access
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https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
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2016-03-22 15:43:03
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Restricted Document
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12897
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UniSZA
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Bakhouche H, Slanař O. Pharmacogenetics in clinical practice. Prague Med Rep, 2012; 113: 251–61. doi:10.2217/pme.12.80. Bannur Z, Bahamas S, Salleh MZ, Teh LK. Pharmacogenomics Based Practice in Malaysia: The Attitude, Knowledge and Adoption by the Healthcare Professionals. IMJM, 2014;13: 41–50. Benzeroual KE, Shah B, Shinde S. Pharmacogenomics: assessing educational exposure, confidence in knowledge and training elements of pharmacists. Per Med, 2012; 9: 387–393. Bernhardt BA, Zayac C, Gordon ES, Wawak L, Pyeritz RE, Gollust SE. Incorporating direct-to-consumer genomic information into patient care: attitudes and experiences of primary care physicians. Per Med, 2012; 9: 683–692. Bonter K, Desjardins C, Currier N, Pun J, Ashbury FD. Personalized medicine in Canada: a survey of adoption and practice in oncology, cardiology and family medicine. BMJ Open, 2011; 1: e000110 Charan J, Biswas T. How to Calculate Sample Size for Different Study Designs in Medical Research? Indian J Psychol Med, 2013; 35: 121- 126. de Denus S, Letarte N, Hurlimann T, Lambert J-P, Lavoie A, Robb L, Sheehan NL, Turgeon J, Vadnais B. An evaluation of pharmacists’ expectations towards pharmacogenomics. Pharmacogenomics, 2013;14: 165-175. Drozda K, Labinov Y, Jiang R, Thomas MR, Wong SS, Patel S, Nutescu EA, Cavallari LH. A pharmacogenetics service experience for pharmacy students, residents, and fellows. Am J Pharm Educ, 2013;77: 175. Field A. Discovering Statistics Using SPSS. 3rd Edition. Sage Publications Ltd, London. 2009 Filiptsova OV, Kobets MN, Kobets YN. Some aspects of genetics and pharmacogenetics understanding by pharmacy students in Ukraine. Egypt J Med Hum Genet, 2015;16: 61–66. Gurwitz D, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Kirchheiner J, Licinio J, Llerena A, Manolopoulos VG, Sheffield LJ, Siest G, Torricelli F, Vasiliou V, Wong S. Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education. Pharmacogenomics J, 2005; 5: 221-225. Hinton P. Statistics explained. Revised ed. Cambridge. Routledge, London and New York. 2014 Islam MZ , Salam A , Helali AM , Rahman Z , Dali WPEW, Ismail S , Rahman NIA , Haque M. Comparative Study of Professionalism of Future Medical Doctors Between Malaysia and Bangladesh. J App Pharm Sci, 2014a; 4: 066-071. Islam MZ, Rahman MF, Mossaddek ASM, Rozario RJ, Iftekhar AFMH, Akhter S, Jahan I, AMH, Dali WPEW, Ismail S, Rahman NIA, Haque M. Bangladeshi Interns' Knowledge of Pharmacology and Therapeutics For Prescribing. J App Pharm Sci, 2014b; 4 (04): 043-051. Jeetu G, Anusha G. Pharmacovigilance: a worldwide master key for drug safety monitoring. J Young Pharm, 2010; 2: 315-320. Mccullough KB, Formea CM, Berg KD, Burzynski JA, Cunningham JL, Ou NN, Rudis MI, Stollings JL, Nicholson WT. Assessment of the pharmacogenomics educational needs of pharmacists. Am J Pharm Educ, 2011; 75: 51. Moen M, Limba J. Assessment of healthcare students’ views on pharmacogenomics at the University of Minnesota. Pharmacogenomics, 2013; 13: 1537-1545. Pallant J. SPSS survival manual. McGraw-Hill Education (UK), 2013. Sadee W. Genomics and personalized medicine. Int J Pharm, 2011; 415: 2-4. Salam A , Yousuf R, Islam MZ, Yesmin F, Helali AM, Alattaraqchi AG, Rao USM, Haque M. Professionalism of future medical professionals in Universiti Sultan Zainal Abidin, Malaysia. Bangladesh J Pharmacol, 2013a; 8: 124-130. Salam A, Haque M, Helali AM, Islam MZ, Mohsena M, Rahman Z, Yesmin F, Rahman NIA, Alattaraqchi AG, Yousuf R. Comparative Study On Professionalism Of Forthcoming Medical Doctors Between Two Private Medical Colleges In Savar, Bangladesh. Int J Pharm Pharm Sci. 2013b; 59: 659-665. Salam A, Haque M, Islam MZ, Helali AM, Yousuf R, Yesmin F, Alattaraqchi AG, Rao USM. Comparative Study of Professionalism of Future Medical Professionals among Three Private Medical Colleges of Bangladesh. Asian J Pharm Clin Res. 2013c; 6: 170-179. Stanek EJ, Sanders CL, Johansen Taber KA, Khalid M, Patel A, Verbrugge R, Agatep BC, Aubert RE, Epstein RS, Frueh FW. Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey. Clin Pharmacol Ther, 2012; 91: 450-458. Steve M. Statistics explained. 1st Edition. Cambridge. London. 1998. Johansen Taber KA, Dickinson BD. Pharmacogenomic knowledge gaps and educational resource needs among physicians in selected specialties. Pharmgenomics Pers Med, 2014; 7: 145-162. The White House. Fact Sheet: President Obama’s Precision Medicine Initiative. 2015. Available from: https://www.whitehouse.gov/the-press-office/2015/01/30/fact-sheetpresident-obama-s-precision-medicine-initiative [Accessed on 27-12- 2015] World Health Organization (WHO). The Importance Of Pharmacovigilance: Monitoring, Safety. Uppsala World Health Organization, United Kingdom. 2002. Available from: http://apps.who.int/medicinedocs/pdf/s4893e/s4893e.pdf [Access ed on 27-12-2015] Yau A, Aziz ABA, Haque M. Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review. J Young Pharmacists, 2015a; 7: 145-154. Yau A, Husain R, Aziz ABA, Johari MKBM, Rahman AFB, Elkalmi RM, Jamilu Y, Haque M. Psychometric Properties of Knowledge, Attitude, and Practice on Pharmacogenovigilance in Drug Safety Questionnaire in Medical and Pharmacy Students: based on Exploratory Factor Analysis. J Appl Phar Sci, 2015; 5 (11): 15-22. Yau A, Husain R, Haque M. A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors. Int J Pharm Res, 2015c; 7: 9-16.
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12897 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=12897 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal image/jpeg inches 96 96 norman 1413 08 08 764 2016-03-22 15:43:03 1413x764 7204-01-FH02-FP-16-05543.jpg UniSZA Private Access Pharmacogenomics: Knowledge, attitude and practice among future doctors and pharmacists-A pilot study Journal of Applied Pharmaceutical Science Rational application of genomics into practice would lead to safer chemotherapy through individualized medicine. The increasing trends of genetic discoveries coupled with increased adoption of pharmacogenomics in developed countries pose challenges to the presence and future healthcare professionals, not only in Malaysia. This research, aimed to assess knowledge, attitude and practice of final-year future healthcare professionals towards pharmacogenomics. A cross-sectional study was conducted by administering self-completed questionnaire (Reliability 0.82) to 247 participants, among which 68.4% responded. More than half were female medical students. The mean knowledge scores in percentage were 57.57±20.2 with a significant difference between the two groups (p = 0.002). Positive attitude, but low practice were observed which differs between pharmacy and medical students, p<0.05. Association between knowledge, attitude and practice, were investigated. The majority has demonstrated good knowledge and attitude towards pharmacogenomics, but with low practice. Studies are required to large sample and to examine barriers to adoption of pharmacogenomics. 6 2 Open Science Publishers LLP Inc. Open Science Publishers LLP Inc. 141-145 Bakhouche H, Slanař O. Pharmacogenetics in clinical practice. Prague Med Rep, 2012; 113: 251–61. doi:10.2217/pme.12.80. Bannur Z, Bahamas S, Salleh MZ, Teh LK. Pharmacogenomics Based Practice in Malaysia: The Attitude, Knowledge and Adoption by the Healthcare Professionals. IMJM, 2014;13: 41–50. Benzeroual KE, Shah B, Shinde S. Pharmacogenomics: assessing educational exposure, confidence in knowledge and training elements of pharmacists. Per Med, 2012; 9: 387–393. Bernhardt BA, Zayac C, Gordon ES, Wawak L, Pyeritz RE, Gollust SE. Incorporating direct-to-consumer genomic information into patient care: attitudes and experiences of primary care physicians. Per Med, 2012; 9: 683–692. Bonter K, Desjardins C, Currier N, Pun J, Ashbury FD. Personalized medicine in Canada: a survey of adoption and practice in oncology, cardiology and family medicine. BMJ Open, 2011; 1: e000110 Charan J, Biswas T. How to Calculate Sample Size for Different Study Designs in Medical Research? Indian J Psychol Med, 2013; 35: 121- 126. de Denus S, Letarte N, Hurlimann T, Lambert J-P, Lavoie A, Robb L, Sheehan NL, Turgeon J, Vadnais B. An evaluation of pharmacists’ expectations towards pharmacogenomics. Pharmacogenomics, 2013;14: 165-175. Drozda K, Labinov Y, Jiang R, Thomas MR, Wong SS, Patel S, Nutescu EA, Cavallari LH. A pharmacogenetics service experience for pharmacy students, residents, and fellows. Am J Pharm Educ, 2013;77: 175. Field A. Discovering Statistics Using SPSS. 3rd Edition. Sage Publications Ltd, London. 2009 Filiptsova OV, Kobets MN, Kobets YN. Some aspects of genetics and pharmacogenetics understanding by pharmacy students in Ukraine. Egypt J Med Hum Genet, 2015;16: 61–66. Gurwitz D, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Kirchheiner J, Licinio J, Llerena A, Manolopoulos VG, Sheffield LJ, Siest G, Torricelli F, Vasiliou V, Wong S. Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education. Pharmacogenomics J, 2005; 5: 221-225. Hinton P. Statistics explained. Revised ed. Cambridge. Routledge, London and New York. 2014 Islam MZ , Salam A , Helali AM , Rahman Z , Dali WPEW, Ismail S , Rahman NIA , Haque M. Comparative Study of Professionalism of Future Medical Doctors Between Malaysia and Bangladesh. J App Pharm Sci, 2014a; 4: 066-071. Islam MZ, Rahman MF, Mossaddek ASM, Rozario RJ, Iftekhar AFMH, Akhter S, Jahan I, AMH, Dali WPEW, Ismail S, Rahman NIA, Haque M. Bangladeshi Interns' Knowledge of Pharmacology and Therapeutics For Prescribing. J App Pharm Sci, 2014b; 4 (04): 043-051. Jeetu G, Anusha G. Pharmacovigilance: a worldwide master key for drug safety monitoring. J Young Pharm, 2010; 2: 315-320. Mccullough KB, Formea CM, Berg KD, Burzynski JA, Cunningham JL, Ou NN, Rudis MI, Stollings JL, Nicholson WT. Assessment of the pharmacogenomics educational needs of pharmacists. Am J Pharm Educ, 2011; 75: 51. Moen M, Limba J. Assessment of healthcare students’ views on pharmacogenomics at the University of Minnesota. Pharmacogenomics, 2013; 13: 1537-1545. Pallant J. SPSS survival manual. McGraw-Hill Education (UK), 2013. Sadee W. Genomics and personalized medicine. Int J Pharm, 2011; 415: 2-4. Salam A , Yousuf R, Islam MZ, Yesmin F, Helali AM, Alattaraqchi AG, Rao USM, Haque M. Professionalism of future medical professionals in Universiti Sultan Zainal Abidin, Malaysia. Bangladesh J Pharmacol, 2013a; 8: 124-130. Salam A, Haque M, Helali AM, Islam MZ, Mohsena M, Rahman Z, Yesmin F, Rahman NIA, Alattaraqchi AG, Yousuf R. Comparative Study On Professionalism Of Forthcoming Medical Doctors Between Two Private Medical Colleges In Savar, Bangladesh. Int J Pharm Pharm Sci. 2013b; 59: 659-665. Salam A, Haque M, Islam MZ, Helali AM, Yousuf R, Yesmin F, Alattaraqchi AG, Rao USM. Comparative Study of Professionalism of Future Medical Professionals among Three Private Medical Colleges of Bangladesh. Asian J Pharm Clin Res. 2013c; 6: 170-179. Stanek EJ, Sanders CL, Johansen Taber KA, Khalid M, Patel A, Verbrugge R, Agatep BC, Aubert RE, Epstein RS, Frueh FW. Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey. Clin Pharmacol Ther, 2012; 91: 450-458. Steve M. Statistics explained. 1st Edition. Cambridge. London. 1998. Johansen Taber KA, Dickinson BD. Pharmacogenomic knowledge gaps and educational resource needs among physicians in selected specialties. Pharmgenomics Pers Med, 2014; 7: 145-162. The White House. Fact Sheet: President Obama’s Precision Medicine Initiative. 2015. Available from: https://www.whitehouse.gov/the-press-office/2015/01/30/fact-sheetpresident-obama-s-precision-medicine-initiative [Accessed on 27-12- 2015] World Health Organization (WHO). The Importance Of Pharmacovigilance: Monitoring, Safety. Uppsala World Health Organization, United Kingdom. 2002. Available from: http://apps.who.int/medicinedocs/pdf/s4893e/s4893e.pdf [Access ed on 27-12-2015] Yau A, Aziz ABA, Haque M. Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review. J Young Pharmacists, 2015a; 7: 145-154. Yau A, Husain R, Aziz ABA, Johari MKBM, Rahman AFB, Elkalmi RM, Jamilu Y, Haque M. Psychometric Properties of Knowledge, Attitude, and Practice on Pharmacogenovigilance in Drug Safety Questionnaire in Medical and Pharmacy Students: based on Exploratory Factor Analysis. J Appl Phar Sci, 2015; 5 (11): 15-22. Yau A, Husain R, Haque M. A Systematic Review of Knowledge, Attitude and Practice towards Pharmacogenomics among Doctors. Int J Pharm Res, 2015c; 7: 9-16.
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| spellingShingle |
Pharmacogenomics: Knowledge, attitude and practice among future doctors and pharmacists-A pilot study
|
| summary |
Rational application of genomics into practice would lead to safer chemotherapy through individualized medicine. The increasing trends of genetic discoveries coupled with increased adoption of pharmacogenomics in developed countries pose challenges to the presence and future healthcare professionals, not only in Malaysia. This research, aimed to assess knowledge, attitude and practice of final-year future healthcare professionals towards pharmacogenomics. A cross-sectional study was conducted by administering self-completed questionnaire (Reliability 0.82) to 247 participants, among which 68.4% responded. More than half were female medical students. The mean knowledge scores in percentage were 57.57±20.2 with a significant difference between the two groups (p = 0.002). Positive attitude, but low practice were observed which differs between pharmacy and medical students, p<0.05. Association between knowledge, attitude and practice, were investigated. The majority has demonstrated good knowledge and attitude towards pharmacogenomics, but with low practice. Studies are required to large sample and to examine barriers to adoption of pharmacogenomics.
|
| title |
Pharmacogenomics: Knowledge, attitude and practice among future doctors and pharmacists-A pilot study
|
| title_full |
Pharmacogenomics: Knowledge, attitude and practice among future doctors and pharmacists-A pilot study
|
| title_fullStr |
Pharmacogenomics: Knowledge, attitude and practice among future doctors and pharmacists-A pilot study
|
| title_full_unstemmed |
Pharmacogenomics: Knowledge, attitude and practice among future doctors and pharmacists-A pilot study
|
| title_short |
Pharmacogenomics: Knowledge, attitude and practice among future doctors and pharmacists-A pilot study
|
| title_sort |
pharmacogenomics: knowledge, attitude and practice among future doctors and pharmacists-a pilot study
|