Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer

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internalnotes Aapro, M. (2005). 5-HT3-receptor antagonists in the management of nausea and vomiting in cancer and cancer treatment. Oncology, 69(2), 97-109. doi:10.1159/000087979 Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., . . . Takeda, F. (1993). The european organization for research and treatment of cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365-376. doi:10.1093/jnci/85.5.365 Basch, E., Prestrud, A. A., Hesketh, P. J., Kris, M. G., Feyer, P. C., Somerfield, M. R., . . . Lyman, G. H. (2011). Antiemetics: American society of clinical oncology clinical practice guideline update. Journal of Clinical Oncology, 29(31), 4189-4198. doi:10.1200/JCO.2010.34.4614 Bauer, K., Garbe, D., & Surburg, H. (1997). Common fragrance and flavor materials: Preparation, properties and uses. Common Fragrance and Flavor Materials, Retrieved from www.scopus.com Bender, C. M., McDaniel, R. W., Murphy-Ende, K., Pickett, M., Rittenberg, C. N., Rogers, M. P., . . . Schwartz, R. N. (2002). Chemotherapy-induced nausea and vomiting. Clinical Journal of Oncology Nursing, 6(2), 94-102. doi:10.1188/02.CJON.94-102 Bloechl-Daum, B., Deuson, R. R., Mavros, P., Hansen, M., & Herrstedt, J. (2006). Delayed nausea and vomiting continue to reduce patients' quality of life after highly and moderately emetogenic chemotherapy despite antiemetic treatment. Journal of Clinical Oncology, 24(27), 4472-4478. doi:10.1200/JCO.2006.05.6382 Börjeson, S., Hursti, T. J., Peterson, C., Fredikson, M., Fürst, C. J., Åvall-Lundqvist, E., & Steineck, G. (1997). Similarities and differences in assessing nausea on a verbal category scale and a visual analogue scale. Cancer Nursing, 20(4), 260-266. doi:10.1097/00002820-199708000-00005 Bourdeanu, L., Frankel, P., Yu, W., Hendrix, G., Pal, S., Badr, L., . . . Luu, T. (2012). Chemotherapy-induced nausea and vomiting in asian women with breast cancer receiving anthracycline-based adjuvant chemotherapy. Journal of Supportive Oncology, 10(4), 149-154. doi:10.1016/j.suponc.2011.10.007 Brown, V., Sitzia, J., Richardson, A., Hughes, J., Hannon, H., & Oakley, C. (2001). The development of the chemotherapy symptom assessment scale (C-SAS): A scale for the routine clinical assessment of the symptom experiences of patients receiving cytotoxic chemotherapy. International Journal of Nursing Studies, 38(5), 497-510. doi:10.1016/S0020-7489(00)00106-1 Cohen, L., De Moor, C. A., Eisenberg, P., Ming, E. E., & Hu, H. (2007). Chemotherapy-induced nausea and vomiting - incidence and impact on patient quality of life at community oncology settings. Supportive Care in Cancer, 15(5), 497-503. doi:10.1007/s00520-006-0173-z Deshpande, P. R., Rajan, S., Sudeepthi, B. L., & Abdul Nazir, C. P. (2011). Patient-reported outcomes: A new era in clinical research. Perspect Clin Res, 2(4), 137-144. Retrieved from www.scopus.com Ernst, E., & Pittler, M. H. (2000). Efficacy of ginger for nausea and vomiting: A systematic review of randomized clinical trials. British Journal of Anaesthesia, 84(3), 367-371. doi:10.1093/oxfordjournals.bja.a013442 Gedney, J. J., Glover, T. L., & Fillingim, R. B. (2004). Sensory and affective pain discrimination after inhalation of essential oils. Psychosomatic Medicine, 66(4), 599-606. doi:10.1097/01.psy.0000132875.01986.47 Geiger, J. L. (2005). The essential oil of ginger, zingiber officinale, and anaesthesia. International Journal of Aromatherapy, 15(1), 7-14. doi:10.1016/j.ijat.2004.12.002 Grunberg, S. M., Deuson, R. R., Mavros, P., Geling, O., Hansen, M., Cruciani, G., . . . Daugaard, G. (2004). Incidence of chemotherapy-induced nausea and emesis after modern antiemetics: Perception versus reality. Cancer, 100(10), 2261-2668. doi:10.1002/cncr.20230 Grunberg, S. M., Osoba, D., Hesketh, P. J., Gralla, R. J., Borjeson, S., Rapoport, B. L., . . . Tonato, M. (2005). Evaluation of new antiemetic agents and definition of antineoplastic agent emetogenicity-an update. Supportive Care in Cancer, 13(2), 80-84. doi:10.1007/s00520-004-0718-y Haniadka, R., Rajeev, A. G., Palatty, P. L., Arora, R., & Baliga, M. S. (2012). Zingiber officinale (ginger) as an anti-emetic in cancer chemotherapy: A review. Journal of Alternative and Complementary Medicine, 18(5), 440-444. doi:10.1089/acm.2010.0737 Hickok, J. T., Roscoe, J. A., Morrow, G. R., Bole, C. W., Zhao, H., Hoelzer, K. L., . . . Fitch, T. R. (2005). 5-hydroxytryptamine-receptor antagonists versus prochlorperazine for control of delayed nausea caused by doxorubicin: A URCC CCOP randomised controlled trial. Lancet Oncology, 6(10), 765-772. doi:10.1016/S1470-2045(05)70325-9 Kim, J. T., Wajda, M., Cuff, G., Serota, D., Schlame, M., Axelrod, D. M., . . . Bekker, A. Y. (2006). Evaluation of aromatherapy in treating postoperative pain: Pilot study. Pain Practice, 6(4), 273-277. doi:10.1111/j.1533-2500.2006.00095.x Lua, P. L., & Zakaria, N. S. (2012). A brief review of current scientific evidence involving aromatherapy use for nausea and vomiting. Journal of Alternative and Complementary Medicine, 18(6), 534-540. doi:10.1089/acm.2010.0862 Montazeri, A. (2008). Health-related quality of life in breast cancer patients: A bibliographic review of the literature from 1974 to 2007. Journal of Experimental and Clinical Cancer Research, 27(1) doi:10.1186/1756-9966-27-32 Price, S., & Price, L. (1995). Aromatherapy for Health Professionals, Retrieved from www.scopus.com Roila, F., Warr, D., Clark-Snow, R. A., Tonato, M., Gralla, R. J., Einhorn, L. H., & Herrstedt, J. (2005). Delayed emesis: Moderately emetogenic chemotherapy. Supportive Care in Cancer, 13(2), 104-108. doi:10.1007/s00520-004-0700-8 Roscoe, J. A., Morrow, G. R., Aapro, M. S., Molassiotis, A., & Olver, I. (2011). Anticipatory nausea and vomiting. Supportive Care in Cancer, 19(10), 1533-1538. doi:10.1007/s00520-010-0980-0 Schnell, F. M. (2003). Chemotherapy-induced nausea and vomiting: The importance of acute antiemetic control. Oncologist, 8(2), 187-198. doi:10.1634/theoncologist.8-2-187 Singh, H., Kaur, K., Singh Banipal, R., Singh, S., & Bala, R. (2014). Quality of life in cancer patients undergoing chemotherapy in a tertiary care center in malwa region of punjab. Indian Journal of Palliative Care, 20(2), 116-122. doi:10.4103/0973-1075.132627 Steflitsch, W., & Steflitsch, M. (2008). Clinical aromatherapy. Journal of Men's Health, 5(1), 74-85. doi:10.1016/j.jomh.2007.11.001 Stringer, J., & Donald, G. (2011). Aromasticks in cancer care: An innovation not to be sniffed at. Complementary Therapies in Clinical Practice, 17(2), 116-121. doi:10.1016/j.ctcp.2010.06.002 White, B. (2007). Ginger: An overview. American Family Physician, 75(11), 1689-1691. Retrieved from www.scopus.com Yeo, W., Mo, F. K. F., Suen, J. J. S., Ho, W. M., Chan, S. L., Lau, W., . . . Zee, B. (2009). A randomized study of aprepitant, ondansetron and dexamethasone for chemotherapy-induced nausea and vomiting in chinese breast cancer patients receiving moderately emetogenic chemotherapy. Breast Cancer Research and Treatment, 113(3), 529-535. doi:10.1007/s10549-008-9957-9 Yusoff, N., Low, W. Y., & Yip, C. H. (2010). The malay version of the european organization for research and treatment of cancer quality of life questionnaire (EORTC-QLQ C30): Reliability and validity study. Int Med J Malaysia, 9(2), 45-50. Retrieved from www.scopus.com
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spelling 12861 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=12861 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal image/jpeg inches 96 96 norman 1421 44 44 717 1421x717 2016-01-31 15:26:24 7168-01-FH02-FSK-16-05255.jpg UniSZA Private Access Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer Complementary Therapies in Medicine Objective: To assess the efficacy of inhaled ginger aromatherapy on nausea, vomiting and health-related quality of life (HRQoL) in chemotherapy breast cancer patients. Design: Single-blind, controlled, randomized cross-over study. Patients received 5-day aromatherapy treatment using either ginger essential oil or fragrance-matched artificial placebo (ginger fragrance oil) which was instilled in a necklace in an order dictated by the treatment group sequence. Setting: Two oncology clinics in the East Coast of Peninsular Malaysia. Main outcome measures: VAS nausea score, frequency of vomiting and HRQoL profile (EORTC QLQ-C30 scores). Results: Sixty female patients completed the study (age = 47.3 ± 9.26 years; Malay = 98.3%; on highly emetogenic chemotherapy = 86.7%). The VAS nausea score was significantly lower after ginger essential oil inhalation compared to placebo during acute phase (P = 0.040) but not sustained for overall treatment effect (treatment effect: F = 1.82, P = 0.183; time effect: F = 43.98, P < 0.001; treatment × time effect: F = 2.04; P = 0.102). Similarly, there was no significant effect of aromatherapy on vomiting [F(1, 58) = 0.29, P = 0.594]. However, a statistically significant change from baseline for global health status (P < 0.001) was detected after ginger essential oil inhalation. A clinically relevant 10 points improvement on role functioning (P = 0.002) and appetite loss (P < 0.001) were also documented while patients were on ginger essential oil. 23 3 Churchill Livingstone Churchill Livingstone 396-404 Aapro, M. (2005). 5-HT3-receptor antagonists in the management of nausea and vomiting in cancer and cancer treatment. Oncology, 69(2), 97-109. doi:10.1159/000087979 Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., . . . Takeda, F. (1993). The european organization for research and treatment of cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365-376. doi:10.1093/jnci/85.5.365 Basch, E., Prestrud, A. A., Hesketh, P. J., Kris, M. G., Feyer, P. C., Somerfield, M. R., . . . Lyman, G. H. (2011). Antiemetics: American society of clinical oncology clinical practice guideline update. Journal of Clinical Oncology, 29(31), 4189-4198. doi:10.1200/JCO.2010.34.4614 Bauer, K., Garbe, D., & Surburg, H. (1997). Common fragrance and flavor materials: Preparation, properties and uses. Common Fragrance and Flavor Materials, Retrieved from www.scopus.com Bender, C. M., McDaniel, R. W., Murphy-Ende, K., Pickett, M., Rittenberg, C. N., Rogers, M. P., . . . Schwartz, R. N. (2002). Chemotherapy-induced nausea and vomiting. Clinical Journal of Oncology Nursing, 6(2), 94-102. doi:10.1188/02.CJON.94-102 Bloechl-Daum, B., Deuson, R. R., Mavros, P., Hansen, M., & Herrstedt, J. (2006). Delayed nausea and vomiting continue to reduce patients' quality of life after highly and moderately emetogenic chemotherapy despite antiemetic treatment. Journal of Clinical Oncology, 24(27), 4472-4478. doi:10.1200/JCO.2006.05.6382 Börjeson, S., Hursti, T. J., Peterson, C., Fredikson, M., Fürst, C. J., Åvall-Lundqvist, E., & Steineck, G. (1997). Similarities and differences in assessing nausea on a verbal category scale and a visual analogue scale. Cancer Nursing, 20(4), 260-266. doi:10.1097/00002820-199708000-00005 Bourdeanu, L., Frankel, P., Yu, W., Hendrix, G., Pal, S., Badr, L., . . . Luu, T. (2012). Chemotherapy-induced nausea and vomiting in asian women with breast cancer receiving anthracycline-based adjuvant chemotherapy. Journal of Supportive Oncology, 10(4), 149-154. doi:10.1016/j.suponc.2011.10.007 Brown, V., Sitzia, J., Richardson, A., Hughes, J., Hannon, H., & Oakley, C. (2001). The development of the chemotherapy symptom assessment scale (C-SAS): A scale for the routine clinical assessment of the symptom experiences of patients receiving cytotoxic chemotherapy. International Journal of Nursing Studies, 38(5), 497-510. doi:10.1016/S0020-7489(00)00106-1 Cohen, L., De Moor, C. A., Eisenberg, P., Ming, E. E., & Hu, H. (2007). Chemotherapy-induced nausea and vomiting - incidence and impact on patient quality of life at community oncology settings. Supportive Care in Cancer, 15(5), 497-503. doi:10.1007/s00520-006-0173-z Deshpande, P. R., Rajan, S., Sudeepthi, B. L., & Abdul Nazir, C. P. (2011). Patient-reported outcomes: A new era in clinical research. Perspect Clin Res, 2(4), 137-144. Retrieved from www.scopus.com Ernst, E., & Pittler, M. H. (2000). Efficacy of ginger for nausea and vomiting: A systematic review of randomized clinical trials. British Journal of Anaesthesia, 84(3), 367-371. doi:10.1093/oxfordjournals.bja.a013442 Gedney, J. J., Glover, T. L., & Fillingim, R. B. (2004). Sensory and affective pain discrimination after inhalation of essential oils. Psychosomatic Medicine, 66(4), 599-606. doi:10.1097/01.psy.0000132875.01986.47 Geiger, J. L. (2005). The essential oil of ginger, zingiber officinale, and anaesthesia. International Journal of Aromatherapy, 15(1), 7-14. doi:10.1016/j.ijat.2004.12.002 Grunberg, S. M., Deuson, R. R., Mavros, P., Geling, O., Hansen, M., Cruciani, G., . . . Daugaard, G. (2004). Incidence of chemotherapy-induced nausea and emesis after modern antiemetics: Perception versus reality. Cancer, 100(10), 2261-2668. doi:10.1002/cncr.20230 Grunberg, S. M., Osoba, D., Hesketh, P. J., Gralla, R. J., Borjeson, S., Rapoport, B. L., . . . Tonato, M. (2005). Evaluation of new antiemetic agents and definition of antineoplastic agent emetogenicity-an update. Supportive Care in Cancer, 13(2), 80-84. doi:10.1007/s00520-004-0718-y Haniadka, R., Rajeev, A. G., Palatty, P. L., Arora, R., & Baliga, M. S. (2012). Zingiber officinale (ginger) as an anti-emetic in cancer chemotherapy: A review. Journal of Alternative and Complementary Medicine, 18(5), 440-444. doi:10.1089/acm.2010.0737 Hickok, J. T., Roscoe, J. A., Morrow, G. R., Bole, C. W., Zhao, H., Hoelzer, K. L., . . . Fitch, T. R. (2005). 5-hydroxytryptamine-receptor antagonists versus prochlorperazine for control of delayed nausea caused by doxorubicin: A URCC CCOP randomised controlled trial. Lancet Oncology, 6(10), 765-772. doi:10.1016/S1470-2045(05)70325-9 Kim, J. T., Wajda, M., Cuff, G., Serota, D., Schlame, M., Axelrod, D. M., . . . Bekker, A. Y. (2006). Evaluation of aromatherapy in treating postoperative pain: Pilot study. Pain Practice, 6(4), 273-277. doi:10.1111/j.1533-2500.2006.00095.x Lua, P. L., & Zakaria, N. S. (2012). A brief review of current scientific evidence involving aromatherapy use for nausea and vomiting. Journal of Alternative and Complementary Medicine, 18(6), 534-540. doi:10.1089/acm.2010.0862 Montazeri, A. (2008). Health-related quality of life in breast cancer patients: A bibliographic review of the literature from 1974 to 2007. Journal of Experimental and Clinical Cancer Research, 27(1) doi:10.1186/1756-9966-27-32 Price, S., & Price, L. (1995). Aromatherapy for Health Professionals, Retrieved from www.scopus.com Roila, F., Warr, D., Clark-Snow, R. A., Tonato, M., Gralla, R. J., Einhorn, L. H., & Herrstedt, J. (2005). Delayed emesis: Moderately emetogenic chemotherapy. Supportive Care in Cancer, 13(2), 104-108. doi:10.1007/s00520-004-0700-8 Roscoe, J. A., Morrow, G. R., Aapro, M. S., Molassiotis, A., & Olver, I. (2011). Anticipatory nausea and vomiting. Supportive Care in Cancer, 19(10), 1533-1538. doi:10.1007/s00520-010-0980-0 Schnell, F. M. (2003). Chemotherapy-induced nausea and vomiting: The importance of acute antiemetic control. Oncologist, 8(2), 187-198. doi:10.1634/theoncologist.8-2-187 Singh, H., Kaur, K., Singh Banipal, R., Singh, S., & Bala, R. (2014). Quality of life in cancer patients undergoing chemotherapy in a tertiary care center in malwa region of punjab. Indian Journal of Palliative Care, 20(2), 116-122. doi:10.4103/0973-1075.132627 Steflitsch, W., & Steflitsch, M. (2008). Clinical aromatherapy. Journal of Men's Health, 5(1), 74-85. doi:10.1016/j.jomh.2007.11.001 Stringer, J., & Donald, G. (2011). Aromasticks in cancer care: An innovation not to be sniffed at. Complementary Therapies in Clinical Practice, 17(2), 116-121. doi:10.1016/j.ctcp.2010.06.002 White, B. (2007). Ginger: An overview. American Family Physician, 75(11), 1689-1691. Retrieved from www.scopus.com Yeo, W., Mo, F. K. F., Suen, J. J. S., Ho, W. M., Chan, S. L., Lau, W., . . . Zee, B. (2009). A randomized study of aprepitant, ondansetron and dexamethasone for chemotherapy-induced nausea and vomiting in chinese breast cancer patients receiving moderately emetogenic chemotherapy. Breast Cancer Research and Treatment, 113(3), 529-535. doi:10.1007/s10549-008-9957-9 Yusoff, N., Low, W. Y., & Yip, C. H. (2010). The malay version of the european organization for research and treatment of cancer quality of life questionnaire (EORTC-QLQ C30): Reliability and validity study. Int Med J Malaysia, 9(2), 45-50. Retrieved from www.scopus.com
spellingShingle Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer
summary Objective: To assess the efficacy of inhaled ginger aromatherapy on nausea, vomiting and health-related quality of life (HRQoL) in chemotherapy breast cancer patients. Design: Single-blind, controlled, randomized cross-over study. Patients received 5-day aromatherapy treatment using either ginger essential oil or fragrance-matched artificial placebo (ginger fragrance oil) which was instilled in a necklace in an order dictated by the treatment group sequence. Setting: Two oncology clinics in the East Coast of Peninsular Malaysia. Main outcome measures: VAS nausea score, frequency of vomiting and HRQoL profile (EORTC QLQ-C30 scores). Results: Sixty female patients completed the study (age = 47.3 ± 9.26 years; Malay = 98.3%; on highly emetogenic chemotherapy = 86.7%). The VAS nausea score was significantly lower after ginger essential oil inhalation compared to placebo during acute phase (P = 0.040) but not sustained for overall treatment effect (treatment effect: F = 1.82, P = 0.183; time effect: F = 43.98, P < 0.001; treatment × time effect: F = 2.04; P = 0.102). Similarly, there was no significant effect of aromatherapy on vomiting [F(1, 58) = 0.29, P = 0.594]. However, a statistically significant change from baseline for global health status (P < 0.001) was detected after ginger essential oil inhalation. A clinically relevant 10 points improvement on role functioning (P = 0.002) and appetite loss (P < 0.001) were also documented while patients were on ginger essential oil.
title Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer
title_full Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer
title_fullStr Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer
title_full_unstemmed Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer
title_short Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer
title_sort effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer