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1860797361980178432
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| building |
INTELEK Repository
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Online Access
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| collectionurl |
https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
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| date |
2018-01-15 12:29:01
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| format |
Restricted Document
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| id |
12412
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UniSZA
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| originalfilename |
6714-01-FH02-FSK-18-13446.pdf
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oai_dc
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| resourceurl |
https://intelek.unisza.edu.my/intelek/pages/view.php?ref=12412
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| spelling |
12412 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=12412 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf 11 Adobe Acrobat Pro DC 20 Paper Capture Plug-in 1.7 2018-01-15 12:29:01 6714-01-FH02-FSK-18-13446.pdf UniSZA Private Access IN VITRO ANTIVIRAL ACTIVITY OF ORTHOSIPHON STAMINEUS EXTRACT AGAINST DENGUE VIRUS TYPE 2 Journal of Fundamental and Applied Sciences In this study, Orthosiphon stamineus aqueous leaves extract was tested against dengue virus type 2. Cytotoxicity screening against Vero cells using MTT assay showed that the CC50 values for extract is 5 mg/ml. The antiviral activity towards Dengue virus type 2 (DENV-2) was investigated by observing the morphological changes, which were further confirmed the cellular viability evaluated by MTT technique. The selective indices (SI = CC50 / EC50) for the extract is 13. These results demonstrate that the extract prepared from O. stamineus possesses phytochemical compound that was non cytotoxic to the cell with potential antiviral activity. These species are good candidates for further activity-monitored fractionation to identify active principles. 10 1S 541-551 http://www.jfas.info/index.php/jfas/issue/view/47
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| spellingShingle |
IN VITRO ANTIVIRAL ACTIVITY OF ORTHOSIPHON STAMINEUS EXTRACT AGAINST DENGUE VIRUS TYPE 2
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| summary |
In this study, Orthosiphon stamineus aqueous leaves extract was tested against dengue virus type 2. Cytotoxicity screening against Vero cells using MTT assay showed that the CC50 values for extract is 5 mg/ml. The antiviral activity towards Dengue virus type 2 (DENV-2) was investigated by observing the morphological changes, which were further confirmed the cellular viability evaluated by MTT technique. The selective indices (SI = CC50 / EC50) for the extract is 13. These results demonstrate that the extract prepared from O. stamineus possesses phytochemical compound that was non cytotoxic to the cell with potential antiviral activity. These species are good candidates for further activity-monitored fractionation to identify active principles.
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| title |
IN VITRO ANTIVIRAL ACTIVITY OF ORTHOSIPHON STAMINEUS EXTRACT AGAINST DENGUE VIRUS TYPE 2
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| title_full |
IN VITRO ANTIVIRAL ACTIVITY OF ORTHOSIPHON STAMINEUS EXTRACT AGAINST DENGUE VIRUS TYPE 2
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| title_fullStr |
IN VITRO ANTIVIRAL ACTIVITY OF ORTHOSIPHON STAMINEUS EXTRACT AGAINST DENGUE VIRUS TYPE 2
|
| title_full_unstemmed |
IN VITRO ANTIVIRAL ACTIVITY OF ORTHOSIPHON STAMINEUS EXTRACT AGAINST DENGUE VIRUS TYPE 2
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| title_short |
IN VITRO ANTIVIRAL ACTIVITY OF ORTHOSIPHON STAMINEUS EXTRACT AGAINST DENGUE VIRUS TYPE 2
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| title_sort |
in vitro antiviral activity of orthosiphon stamineus extract against dengue virus type 2
|