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1860797315591176192
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INTELEK Repository
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Online Access
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https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
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2024-08-26 20:17:14
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Restricted Document
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12212
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UniSZA
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1. Kearney PM, Whelton M, Reynolds K, Whelton PK, He J. Global burden of hypertension: analysis of world-wide data. Lancet 2005; 365(9455): 217-23. 2. Boon NA, Colledge NR, Walker BR, Hunter JAA. Davidson’s Principles and Practice of Medicine. 20th ed. India: Elsevier Limited; 2006. 3. Uddin MN, Ali MZ, Jahan NWB, Rashid MA, Sultan MK, Hoque MA, et al. Study of serum insulin level in hypertensive patients. Cardiovasc J. 2011; 4(1): 13-6. 4. Islam AKM, Majumder AAS. Hypertension in Bangladesh-a review. Indian Heart J. 2012; 64(03): 323. 5. Pessin JH, Saltiel AR. Signaling pathways in insulin action: molecular targets of insulin resistance. J Clin Invest. 2000; 106(2): 165- 9. 6. Chiarelli F, Marcovecchio ML. Insulin resistance and obesity in childhood. Eur J Endocrinol. 2008; 159(1): 567-74. 7. Haffner SM, Valdez RA, Hazuda HP, Mitchell BD, Morales PA, Stern MP. Prospective analysis of the insulin-resistance syndrome (syndrome X). Diabetes 1992; 41(6): 715-22. 8. Welborn TA, Breckenridge A, Dollery CT, Fraser TR. Seruminsulin in essential hypertension and in peripheral vascular disease. Lancet 1966; 1(7451): 1336-7. 9. Penesova A, Cizamarova E, Belan V, Blazicek P, Imrich R, Vlcek M, et al. Insulin resistance in young, lean male subjects with essential hypertension. J Hum Hypertens. 2011; 25(6): 391-400. 10. Kronenberg F, Rich SS, Sholinsky P, Arnett DK, Province ME, Myers RH, et al. Insulin and hypertension in the NHLBI family heart study. Am J Hypertens. 2000; 13(3): 240-50. 11. Baba T, Kodama T, Tomiyama T, Fujita N, Takebe K. Hyperinsulinemia and blood pressure in non-obese middle-aged subjects with normal glucose tolerance. Tohoku J Exp Med. 1991; 165(3): 229-35. 12. Every NR, Boyko EJ, Keane EM, Marshall JA, Rewers M, Hamman RF. Blood pressure, insulin, and C-peptide levels in San Luis Valley, Colorado. Diabetes Care 1993; 16(12): 1543-50. 13. Matthews DR, Hosker JP, Rudenskin AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Dibetologia 1985; 28(7): 412-9. 14. Sloniger JA, Saengsirisuwan V, Diehl CJ, Dokken BB, Lailerd N, Lemieux AM, et al. Defective insulin signaling in skeletal muscle of the hypertensive TG (mREN2) 27 rat. Am J Physiol Endocrinol Metab. 2005; 288(6): E1074-81.
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6512-01-FH02-FP-15-03614.pdf
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https://intelek.unisza.edu.my/intelek/pages/view.php?ref=12212
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12212 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=12212 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf Adobe Acrobat Pro DC 20 Paper Capture Plug-in with ClearScan 8 1.6 Adobe Acrobat Pro DC 20.6.20042 . . 2024-08-26 20:17:14 6512-01-FH02-FP-15-03614.pdf UniSZA Private Access Correlation Study of Insulin Resistance and Essential Hypertension among Bangladeshi Male Volunteers Journal of Young Pharmacists Background: The patients with essential hypertension are increasing all over the world. There may be development of insulin resistance and hyperinsulinemia in essential hypertension. An association between essential hypertension and defective insulin secretion has been identified. Insulin resistance is the fundamental defect in the development of type 2 diabetes mellitus, hypertension and cardiovascular diseases. Objective: To observe the insulin resistance in adult male with essential hypertension. Methods: This is a cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, Bangladesh from July 2012 to June 2013. A total number of 150 male subjects were selected with age ranging from 25-45 years. Seventy five male essential hypertensives were enrolled from Out- patient Department of Medicine, Dhaka Medical College Hospital, Dhaka. Otherwise healthy 75 of similar age were studied as control. Insulin resistance was assessed by HOMA-IR method. Fasting serum insulin level was measured by ELISA and fasting blood glucose by glucose oxidase method. Unpaired Student’s ‘t’ and Pearson’s correlation coefficient (r) tests were performed for statistical analyses. Results: Current study reveals that essential hypertension has positive and significant relationship with fasting serum insulin level and insulin resistance. Conclusion: Incidence of insulin resistance is higher in essential hypertensive subjects in comparison to the control subjects. More in-depth prospective research is advocated to find remedies for common Bangladeshi patients. 7 3 200-205 1. Kearney PM, Whelton M, Reynolds K, Whelton PK, He J. Global burden of hypertension: analysis of world-wide data. Lancet 2005; 365(9455): 217-23. 2. Boon NA, Colledge NR, Walker BR, Hunter JAA. Davidson’s Principles and Practice of Medicine. 20th ed. India: Elsevier Limited; 2006. 3. Uddin MN, Ali MZ, Jahan NWB, Rashid MA, Sultan MK, Hoque MA, et al. Study of serum insulin level in hypertensive patients. Cardiovasc J. 2011; 4(1): 13-6. 4. Islam AKM, Majumder AAS. Hypertension in Bangladesh-a review. Indian Heart J. 2012; 64(03): 323. 5. Pessin JH, Saltiel AR. Signaling pathways in insulin action: molecular targets of insulin resistance. J Clin Invest. 2000; 106(2): 165- 9. 6. Chiarelli F, Marcovecchio ML. Insulin resistance and obesity in childhood. Eur J Endocrinol. 2008; 159(1): 567-74. 7. Haffner SM, Valdez RA, Hazuda HP, Mitchell BD, Morales PA, Stern MP. Prospective analysis of the insulin-resistance syndrome (syndrome X). Diabetes 1992; 41(6): 715-22. 8. Welborn TA, Breckenridge A, Dollery CT, Fraser TR. Seruminsulin in essential hypertension and in peripheral vascular disease. Lancet 1966; 1(7451): 1336-7. 9. Penesova A, Cizamarova E, Belan V, Blazicek P, Imrich R, Vlcek M, et al. Insulin resistance in young, lean male subjects with essential hypertension. J Hum Hypertens. 2011; 25(6): 391-400. 10. Kronenberg F, Rich SS, Sholinsky P, Arnett DK, Province ME, Myers RH, et al. Insulin and hypertension in the NHLBI family heart study. Am J Hypertens. 2000; 13(3): 240-50. 11. Baba T, Kodama T, Tomiyama T, Fujita N, Takebe K. Hyperinsulinemia and blood pressure in non-obese middle-aged subjects with normal glucose tolerance. Tohoku J Exp Med. 1991; 165(3): 229-35. 12. Every NR, Boyko EJ, Keane EM, Marshall JA, Rewers M, Hamman RF. Blood pressure, insulin, and C-peptide levels in San Luis Valley, Colorado. Diabetes Care 1993; 16(12): 1543-50. 13. Matthews DR, Hosker JP, Rudenskin AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Dibetologia 1985; 28(7): 412-9. 14. Sloniger JA, Saengsirisuwan V, Diehl CJ, Dokken BB, Lailerd N, Lemieux AM, et al. Defective insulin signaling in skeletal muscle of the hypertensive TG (mREN2) 27 rat. Am J Physiol Endocrinol Metab. 2005; 288(6): E1074-81.
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| spellingShingle |
Correlation Study of Insulin Resistance and Essential Hypertension among Bangladeshi Male Volunteers
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| subject |
.
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| summary |
Background: The patients with essential hypertension are increasing all over the world. There may be development of insulin resistance and hyperinsulinemia in essential hypertension. An association between essential hypertension and defective insulin secretion has been identified. Insulin resistance is the fundamental defect in the development of type 2 diabetes mellitus, hypertension and cardiovascular diseases. Objective: To observe the insulin resistance in adult male with essential hypertension. Methods: This is a cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, Bangladesh from July 2012 to June 2013. A total number of 150 male subjects were selected with age ranging from 25-45 years. Seventy five male essential hypertensives were enrolled from Out- patient Department of Medicine, Dhaka Medical College Hospital, Dhaka. Otherwise healthy 75 of similar age were studied as control. Insulin resistance was assessed by HOMA-IR method. Fasting serum insulin level was measured by ELISA and fasting blood glucose by glucose oxidase method. Unpaired Student’s ‘t’ and Pearson’s correlation coefficient (r) tests were performed for statistical analyses. Results: Current study reveals that essential hypertension has positive and significant relationship with fasting serum insulin level and insulin resistance. Conclusion: Incidence of insulin resistance is higher in essential hypertensive subjects in comparison to the control subjects. More in-depth prospective research is advocated to find remedies for common Bangladeshi patients.
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| title |
Correlation Study of Insulin Resistance and Essential Hypertension among Bangladeshi Male Volunteers
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| title_full |
Correlation Study of Insulin Resistance and Essential Hypertension among Bangladeshi Male Volunteers
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| title_fullStr |
Correlation Study of Insulin Resistance and Essential Hypertension among Bangladeshi Male Volunteers
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| title_full_unstemmed |
Correlation Study of Insulin Resistance and Essential Hypertension among Bangladeshi Male Volunteers
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| title_short |
Correlation Study of Insulin Resistance and Essential Hypertension among Bangladeshi Male Volunteers
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| title_sort |
correlation study of insulin resistance and essential hypertension among bangladeshi male volunteers
|