Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review

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internalnotes 1. Spear BB, Heath-Chiozzi M, Huff J. Clinical application of pharmacogenetics. Trends Mol Med. 2001; 7(5): 201-4. 2. Davies EC, Green CF, Mottram DR, Pirmohamed M. Adverse drug reactions in hospitals: a narrative review. Curr Drug Saf. 2007; 2(1): 79-87. 3. Wiffen P, Gill M, Edwards J, Moore A. Adverse drug reactions in hospital patients A systematic review of the prospective and retrospective studies. Bandolier Extra. 2002; (June) 101(4): 1-15. 4. Merriam-Webster Dictoinary. An Encyclopedia Britannica Company. Available form http://www.merriam-webster.com/ dictionary/pharmacogenomics 5. Goldstein DB, Need AC, Singh R, Sisodiya SM. Potential Genetic Causes of Heterogeneity of Treatment Effects. Am J Med. 2007;120(4 SUPPL.). 6. Garrod Archibald E. The Incidence of Alkaptonuria: Astudy in Chemical Individuality. Lancet. 1902; 2(3): 1616-20. 7. Shah A. Pharmacy Intervention in the Medication - Use Process the Role of Pharmacists in Improving Patient Safety. International Pharmaceutical Federation (FIP), Den Haag, Netherlands 2009. Available from https://www.fip.org/files/fip/Patient%20Safety/ PatientSafetyAdvidShah.pdf 8. Kennedy MJ, Phan H, Benavides S, Potts A, Sorensen S. The role of the pediatric pharmacist in personalized medicine and clinical pharmacogenomics for children: pediatric pharmacogenomics working group. J Pediatr Pharmacol Ther. 2011;16(2): 118-122. 9. Newton R, Lithgow J, Li A, Po W, Bennett C, Farndon P. How will pharmacogenetics impact on pharmacy practice ? Pharmacists views and educational priorities impact on pharmacy practice ? Pharmacists ’ views and educational priorities Contents. 2007; (November) 10. Ginsburg GS, Willard HF. Genomic and personalized medicine: foundations and applications. Transl Res. 2009; 154(6): 277-87. 11. Gage BF, Lesko LJ. Pharmacogenetics of warfarin: Regulatory, scientific, and clinical issues. J Thromb Thrombolysis. 2008; 25(1): 45-51. 12. Bannur Z, S B, MZ S, LKT. Pharmacogenomics Based Practice in Malaysia : The Attitude , Knowledge and Adoption by the Healthcare Demographics of Respondents. IMJM. 2014; 13(1): 41-50. 13. Bakhouche H, Slanař O. Pharmacogenetics in clinical practice. Prague Med Rep. 2012; 113(4): 251-61. 14. Brockmöller J, Tzvetkov M V. Pharmacogenetics: Data, concepts and tools to improve drug discovery and drug treatment. Eur J Clin Pharmacol. 2008; 64(2): 133-57. 15. Benzeroual KE, Shah B, Shinde S. Pharmacogenomics: assessing educational exposure, confidence in knowledge and training elements of pharmacists. Per Med. 2012;9(4):387-393. 16. Latif D, McKay AB. Pharmacogenetics and Pharmacogenomics Instruction in Colleges and Schools of Pharmacy in the United States. Am J Pharm Educ. 2005; 69(2): 23. 17. Mccullough KB, Formea CM, Berg KD, et al. Assessment of the pharmacogenomics educational needs of pharmacists. Am J Pharm Educ. 2011; 75(3): 1-6. 18. Roederer MW, Van Riper M, Valgus J, Knafl G, McLeod H. Knowledge, attitudes and education of pharmacists regarding pharmacogenetic testing. Per Med. 2012; 9(1): 19-27. 19. Tuteja S, Haynes K, Zayac C, Sprague JE, Bernhardt B, Pyeritz R. Community pharmacists attitudes towards clinical utility and ethical implications of pharmacogenetic testing. Per Med. 2013;10(8): 793-800. 20. Powell KP, Cogswell W, Christianson C, et al. Primary care physicians’ awareness, experience and opinions of direct-toconsumer genetic testing. J Genet Couns. 2012; 21(1): 113-16. Formea CM, Nicholson WT, McCullough KB, et al. Development and evaluation of a pharmacogenomics educational program for pharmacists. Am J Pharm Educ. 2013; 77(1): 10. 21. Parvaz Madadi, Ehijie FO, Enato EOB. Perceptions of health care professionals towards pharmacogenomics in Nigeria: Preliminary Results. West African J Pharm. 2011; 22(2): 97-101. 22. De Denus S, Letarte N, Hurlimann T, et al. An evaluation of pharmacists expectations towards pharmacogenomics. Pharmacogenomics. 2013; 14(2): 165-75. 23. McMahon T, Tucci J. The perceptions of pharmacists in Victoria, Australia on pharmacogenetics and its implications. Pharm Pract (Granada) 2011; 9(3): 141-7. 24. Filiptsova OV, Kobets MN, Kobets YN. Some aspects of genetics and pharmacogenetics understanding by pharmacy students in Ukraine. Egypt J Med Hum Genet. 2014. 25. Zembles T. An inservice program on pharmacogenetics to individualize drug therapy. Am J Pharm Educ. 2010; 74(1): 10. 26. Murphy JE, Green JS, Adams LA, Squire RB, Kuo GM, Mckay A. Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States. Am J Pharm Educ. 2010; 74(1): 7.
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spelling 12211 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=12211 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf Adobe Acrobat Pro DC 20 Paper Capture Plug-in with ClearScan 12 1.6 Adobe Acrobat Pro DC 20.6.20042 . . 2024-08-26 20:16:16 6511-01-FH02-FP-15-03613.pdf UniSZA Private Access Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review Journal of Young Pharmacists Background: Pharmacists are furnished with expert drug knowledge and have been considered as valuable resource of drug information, therefore, are well positioned to play a leading role in the application of pharmacogenomics (PG) in to clinical practice. This might prevent Chemotherapy related adverse events and improve patient outcomes, despite the ethical, privacy concerns and potential implications of lifelong genetic-data. Methods: This review is to evaluate and digest the various studies on Knowledge, Attitudes and Practice concerning pharmacogenomics among pharmacists and to suggest future research areas. 13 English published studies from 2004 to 2014 were selected. Studies involving Pharmacists of different area of practice and covering research from different continents were selected. Only studies on attitudes, knowledge and practice concerning pharmacogenetics among pharmacists from 2004 to 2014, and research articles published in English were selected. Non-research articles, studies done on general public; studies conducted among other healthcare professionals; studies on genetics of diseases or toxicogenetics were excluded. Results: Knowledge and practice regarding pharmacogenetics among pharmacists were poor despite good attitudes. There was knowledge advancement from 38% in 2005 to more than 50% 2013 in some countries. Some barriers to adoption of pharmacogenomics into patient care and interventional recommendations were highlighted. Conclusion: there is an urgent call for additional training of Pharmacogenomics among pharmacists and to incorporate pharmacogenomics into curriculum of pharmacy schools. Pharmacists and future pharmacists should be trained on how to critically evaluate the use, efficacy, and safety of available pharmacogenetic testing. 7 3 EManuscript Services EManuscript Services 145-154 1. Spear BB, Heath-Chiozzi M, Huff J. Clinical application of pharmacogenetics. Trends Mol Med. 2001; 7(5): 201-4. 2. Davies EC, Green CF, Mottram DR, Pirmohamed M. Adverse drug reactions in hospitals: a narrative review. Curr Drug Saf. 2007; 2(1): 79-87. 3. Wiffen P, Gill M, Edwards J, Moore A. Adverse drug reactions in hospital patients A systematic review of the prospective and retrospective studies. Bandolier Extra. 2002; (June) 101(4): 1-15. 4. Merriam-Webster Dictoinary. An Encyclopedia Britannica Company. Available form http://www.merriam-webster.com/ dictionary/pharmacogenomics 5. Goldstein DB, Need AC, Singh R, Sisodiya SM. Potential Genetic Causes of Heterogeneity of Treatment Effects. Am J Med. 2007;120(4 SUPPL.). 6. Garrod Archibald E. The Incidence of Alkaptonuria: Astudy in Chemical Individuality. Lancet. 1902; 2(3): 1616-20. 7. Shah A. Pharmacy Intervention in the Medication - Use Process the Role of Pharmacists in Improving Patient Safety. International Pharmaceutical Federation (FIP), Den Haag, Netherlands 2009. Available from https://www.fip.org/files/fip/Patient%20Safety/ PatientSafetyAdvidShah.pdf 8. Kennedy MJ, Phan H, Benavides S, Potts A, Sorensen S. The role of the pediatric pharmacist in personalized medicine and clinical pharmacogenomics for children: pediatric pharmacogenomics working group. J Pediatr Pharmacol Ther. 2011;16(2): 118-122. 9. Newton R, Lithgow J, Li A, Po W, Bennett C, Farndon P. How will pharmacogenetics impact on pharmacy practice ? Pharmacists views and educational priorities impact on pharmacy practice ? Pharmacists ’ views and educational priorities Contents. 2007; (November) 10. Ginsburg GS, Willard HF. Genomic and personalized medicine: foundations and applications. Transl Res. 2009; 154(6): 277-87. 11. Gage BF, Lesko LJ. Pharmacogenetics of warfarin: Regulatory, scientific, and clinical issues. J Thromb Thrombolysis. 2008; 25(1): 45-51. 12. Bannur Z, S B, MZ S, LKT. Pharmacogenomics Based Practice in Malaysia : The Attitude , Knowledge and Adoption by the Healthcare Demographics of Respondents. IMJM. 2014; 13(1): 41-50. 13. Bakhouche H, Slanař O. Pharmacogenetics in clinical practice. Prague Med Rep. 2012; 113(4): 251-61. 14. Brockmöller J, Tzvetkov M V. Pharmacogenetics: Data, concepts and tools to improve drug discovery and drug treatment. Eur J Clin Pharmacol. 2008; 64(2): 133-57. 15. Benzeroual KE, Shah B, Shinde S. Pharmacogenomics: assessing educational exposure, confidence in knowledge and training elements of pharmacists. Per Med. 2012;9(4):387-393. 16. Latif D, McKay AB. Pharmacogenetics and Pharmacogenomics Instruction in Colleges and Schools of Pharmacy in the United States. Am J Pharm Educ. 2005; 69(2): 23. 17. Mccullough KB, Formea CM, Berg KD, et al. Assessment of the pharmacogenomics educational needs of pharmacists. Am J Pharm Educ. 2011; 75(3): 1-6. 18. Roederer MW, Van Riper M, Valgus J, Knafl G, McLeod H. Knowledge, attitudes and education of pharmacists regarding pharmacogenetic testing. Per Med. 2012; 9(1): 19-27. 19. Tuteja S, Haynes K, Zayac C, Sprague JE, Bernhardt B, Pyeritz R. Community pharmacists attitudes towards clinical utility and ethical implications of pharmacogenetic testing. Per Med. 2013;10(8): 793-800. 20. Powell KP, Cogswell W, Christianson C, et al. Primary care physicians’ awareness, experience and opinions of direct-toconsumer genetic testing. J Genet Couns. 2012; 21(1): 113-16. Formea CM, Nicholson WT, McCullough KB, et al. Development and evaluation of a pharmacogenomics educational program for pharmacists. Am J Pharm Educ. 2013; 77(1): 10. 21. Parvaz Madadi, Ehijie FO, Enato EOB. Perceptions of health care professionals towards pharmacogenomics in Nigeria: Preliminary Results. West African J Pharm. 2011; 22(2): 97-101. 22. De Denus S, Letarte N, Hurlimann T, et al. An evaluation of pharmacists expectations towards pharmacogenomics. Pharmacogenomics. 2013; 14(2): 165-75. 23. McMahon T, Tucci J. The perceptions of pharmacists in Victoria, Australia on pharmacogenetics and its implications. Pharm Pract (Granada) 2011; 9(3): 141-7. 24. Filiptsova OV, Kobets MN, Kobets YN. Some aspects of genetics and pharmacogenetics understanding by pharmacy students in Ukraine. Egypt J Med Hum Genet. 2014. 25. Zembles T. An inservice program on pharmacogenetics to individualize drug therapy. Am J Pharm Educ. 2010; 74(1): 10. 26. Murphy JE, Green JS, Adams LA, Squire RB, Kuo GM, Mckay A. Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States. Am J Pharm Educ. 2010; 74(1): 7.
spellingShingle Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review
subject .
summary Background: Pharmacists are furnished with expert drug knowledge and have been considered as valuable resource of drug information, therefore, are well positioned to play a leading role in the application of pharmacogenomics (PG) in to clinical practice. This might prevent Chemotherapy related adverse events and improve patient outcomes, despite the ethical, privacy concerns and potential implications of lifelong genetic-data. Methods: This review is to evaluate and digest the various studies on Knowledge, Attitudes and Practice concerning pharmacogenomics among pharmacists and to suggest future research areas. 13 English published studies from 2004 to 2014 were selected. Studies involving Pharmacists of different area of practice and covering research from different continents were selected. Only studies on attitudes, knowledge and practice concerning pharmacogenetics among pharmacists from 2004 to 2014, and research articles published in English were selected. Non-research articles, studies done on general public; studies conducted among other healthcare professionals; studies on genetics of diseases or toxicogenetics were excluded. Results: Knowledge and practice regarding pharmacogenetics among pharmacists were poor despite good attitudes. There was knowledge advancement from 38% in 2005 to more than 50% 2013 in some countries. Some barriers to adoption of pharmacogenomics into patient care and interventional recommendations were highlighted. Conclusion: there is an urgent call for additional training of Pharmacogenomics among pharmacists and to incorporate pharmacogenomics into curriculum of pharmacy schools. Pharmacists and future pharmacists should be trained on how to critically evaluate the use, efficacy, and safety of available pharmacogenetic testing.
title Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review
title_full Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review
title_fullStr Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review
title_full_unstemmed Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review
title_short Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review
title_sort knowledge, attitude and practice concerning pharmacogenomics among pharmacists: a systematic review