Comparison of chemical profile and biological activities of different plant parts of Ficus deltoidea Jack var. trengganuensis
| Format: | Restricted Document |
|---|
| _version_ | 1860797186157051904 |
|---|---|
| building | INTELEK Repository |
| collection | Online Access |
| collectionurl | https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 |
| date | 2015-04-27 14:13:59 |
| format | Restricted Document |
| id | 11702 |
| institution | UniSZA |
| internalnotes | 1. Mustaffa F, Indurkar J, Ali NIM, Hanapi A, Shah M, Ismail S, Mansor SM. A review of Malaysian plants with potential antidiabetic activity. Journal of Pharmacy Research 2011; 4(11):4217-4224. 2. Sulaiman MR, Hussain MK, Zakaria ZA, Somchit MN, Moin, S, Mohamad AS et al. Evaluation of the antinociceptive activity of Ficus deltoidea aqueous extract. Fitoterapia 2008; 79:557-561. 3. Hakiman M and Maziah M. Non enzymatic and enzymatic antioxidant activities in aqueous extract of different Ficus deltoidea accessions. Journal of Medicinal Plants Research 2009; 3(3):120-131. 4. Norra I. Free radical scavenging activity and phenolic content of Ficus deltoidea accessions MFD4 and MFD6 leaves. Journal Tropical Agricultural and Food Science 2011; 39(1): 1-8 5. Adam Z, Hamid M, Ismail A, Ismail S. Effect of Ficus deltoidea extracts on hepatic basal and insulin-stimulated glucose uptake.Journal of Biological Sciences 2009; 9(8): 796-803. 6. Adam Z, Khamis S, Ismail A, Hamid M. Inhibitory properties of Ficus deltoidea on α-glucosidase activity. Research Journal of Medicinal Plant 2010; 4(2):61-75. 7. Adam Z, Khamis S, Ismail A, Hamid M. Ficus deltoidea: A potential alternative medicine for diabetes mellitus. Evidence-Based Complementary and Alternative Medicine 2012; Article ID: 632763:12 8. Oh M-J, Hamid AM, Ngadiran S, Seo Y-K, Sarmidi MR Park CS. Ficus deltoidea (Mas cotek) extract exerted anti-melanogenic activity by preventing tyrosinase activity in vitro and by suppressing tyrosinase gene expression in B16F1 melanoma cells. Arch. Dermatol. Res 2011; 303:161-170. 9. Hasham R, Choi HK, Sarmidi MR, Park CS. Protective effects of a Ficus deltoidea (Mas cotek) extract against UVB-induced photoageing in skin cells. Biotechnology and Bioprocess Engineering 2013; 18:185-193. 10. Corner, EJH. The complex of Ficus deltoidea; a recent invasion of the Sunda shelf. Phil. Trans. R. Soc. Lond 1969; 256:281-317. 11. Mohd KS, Azemin A, Hamil MSR, Abu Bakar AR, Dharmaraj S, Hamdan MR, et al. Application of HPTLC and FTIR profiling coupled with chemometrics for the differentiation of the varieties of Ficus deltoidea Jack. Asian Journal of Pharmaceutical and Clinical Research 2014; 7(5): 110-116. 12. Adam Z, Hamid M, Ismail A, Khamis S. Effect of Ficus deltoidea aqueous extract on blood glucose level in normal and mild diabetic rats. Jurnal Sains Kesihatan Malaysia 2007; 5(2): 9-16. 13. Syed Aris SR, Mustafa S, Ahmat N, Mohd Jaafar F and Ahmad R. Phenolic content and antioxidant activity of fruits of Ficus deltoidea var. angustifolia sp. The Malaysian Journal of Analytical Sciences 2009; 13(2): 146-150. 14. Khairi HM, Afifah MYN, Somchlt MN and Moin S. Anti-inflammatory properties of aqueous fruit extract of Ficus deltoidea Jack var. angustifolia (Miq.) Corner. Medicinal and Aromatic Plants Seminar (MAPS 2010) August 3– 4 2010 15. Bunawan H, Mat Amin N, Bunawan SN, Baharum SN and Mohd Noor N. Ficus deltoidea: A review on Its Phytochemical Pharmacological Importance. Evidence-Based Complementary and Alternative Medicine 2014; 8 16. Misbah H, Abdul Aziz A and Aminudin N. Antidiabetic and antioxidant properties of Ficus deltoidea fruit extracts and fractions. BMC Complementary & Alternative Medicine 2013; 13:118. 17. Aminudin N, Sin CY, Chee ES, Nee KI, Renxin L. Blood glucose lowering effect of Ficus deltoidea aqueous extract. Malaysian Journal of Science 2007; 26 (1):73-78. 18. Dzolin S, Aris SSR, Ahmad R. and Mat Zain M. Radical scavenging and neurotoxicity of four varieties of Ficus deltoidea. International Conference on Science and Social Research (CSSR). December 5-7 2010, Kuala Lumpur, Malaysia 19. Mayur B, Sandesh S, Shruti S. and Sung-Yum S. Antioxidant and α-glucosidase inhibitory properties of Carpesium abrotanoides L. Journal of Medicinal Plants Research 2010; 4(15): 1547-1553. 20. Marston A and Hostettmann K. Separation and Quantification of Flavonoids. In: Andersen Ø. M. and Markham K. R., editor. Flavonoids: chemistry, biochemistry and applications. London (NY): CRC Press Taylor & Francis Group; 2006. p. 1-36 21. Bougatef A, Hajji M, Balti R, Lassoued I, Triki-Ellouz Y. and Nasri M. Antioxidant and free radicalscavenging activities of smooth hound (Mustelus mustelus) muscle protein hydrolysates obtained by gastroinstenal proteases. Food Chemistry 2009; 114: 1198-1205. 22. Shimada K, Fujikawa K, Yahara K and Nakamura T. Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion. Journal of Agriculture and Food Chemistry 1992; 40: 945-948. 23. Farsi E, Shafaei A, Yee Hor S, Khadeer Ahamed BM, Yam MF, Attitalla IH, Asmawi, MZ, and Ismail Z. Correlation between enzymes inhibitory effects and antioxidant activities of standardized fractions of methanolic extract obtained from Ficus deltoidea leaves. African Journal of Biotechnology. 2011;10(67): 15184-15194. 24. Van de Laar FA, Lucassen PL, Akkermans RP, van de Lisdonk EH, Rutten GE and van Weel C. Α-Glucosidase inhibitors for patients with type 2 diabetes. Diabetes Care 2005; 28: 166-175. 25. Kalra S. Alpha glucosidase inhibitors. J. Pak. Med. Assoc. 214;64(4): 474-476. 26. Cheng AYY and Fantus GI. Oral antihyperglycemic therapy for type 2 diabetes mellitus. Canadian Medical Association 2005; 172(2):213-226. |
| originalfilename | 5974-01-FH02-FBIM-15-02868.jpg |
| person | UniSZA Unisza unisza |
| recordtype | oai_dc |
| resourceurl | https://intelek.unisza.edu.my/intelek/pages/view.php?ref=11702 |
| spelling | 11702 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=11702 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal UniSZA Unisza unisza image/jpeg inches 96 96 1417 752 65 65 2015-04-27 14:13:59 1417x752 5974-01-FH02-FBIM-15-02868.jpg UniSZA Private Access Comparison of chemical profile and biological activities of different plant parts of Ficus deltoidea Jack var. trengganuensis International Journal of Pharmacognosy and Phytochemical Research Ficus deltoidea var. Trengganuensis (FDT) is one of the variety of a highly potential herbs, Ficus deltoidea Jack. This herb has pharmacologically been shown to possess numerous biological activities. Commonly, only leaves have been used medicinally. In order to assess whether other part such as fig and stem can also be used for medicinal purposes, chemical profile and biological activities were compared. Samples that consist of leaves, figs and stems were collected from four locations in Trengganu state, east coast of Peninsular Malaysia. Thin layer chromatography (TLC) and Fourier transform infrared (FTIR) were used to assess the chemical profile. Two compounds, vitexin and isovitexin were used as authentication marker of FDT. A good separation of the chemical components and marker in all sample with distinct spots observed on fig TLC chromatogram at the solvent system of ethyl acetate: formic acid (0.1%): methanol (4:6:2 v/v/v). FTIR fingerprints also exhibit different profile for fig, stem and leaf extract. Principle component analysis on FTIR data revealed that figs from four locations clustered into one group in positive PC2 quadrant suggest that fig has specific constituents, which discriminate them from leaf and stem. Biological activities were assessed by 2, 2-diphenyl-1- picrylhydrazyl (DPPH) inhibition and α-glucosidase inhibition assays. Comparison between plant parts discovered that figs from all locations have the highest inhibition on both activities compared to leaves and stems. Finding from this study revealed that figs of FDT could also be consumed for therapeutic purposes in addition to the leaves. 7 2 325-332 1. Mustaffa F, Indurkar J, Ali NIM, Hanapi A, Shah M, Ismail S, Mansor SM. A review of Malaysian plants with potential antidiabetic activity. Journal of Pharmacy Research 2011; 4(11):4217-4224. 2. Sulaiman MR, Hussain MK, Zakaria ZA, Somchit MN, Moin, S, Mohamad AS et al. Evaluation of the antinociceptive activity of Ficus deltoidea aqueous extract. Fitoterapia 2008; 79:557-561. 3. Hakiman M and Maziah M. Non enzymatic and enzymatic antioxidant activities in aqueous extract of different Ficus deltoidea accessions. Journal of Medicinal Plants Research 2009; 3(3):120-131. 4. Norra I. Free radical scavenging activity and phenolic content of Ficus deltoidea accessions MFD4 and MFD6 leaves. Journal Tropical Agricultural and Food Science 2011; 39(1): 1-8 5. Adam Z, Hamid M, Ismail A, Ismail S. Effect of Ficus deltoidea extracts on hepatic basal and insulin-stimulated glucose uptake.Journal of Biological Sciences 2009; 9(8): 796-803. 6. Adam Z, Khamis S, Ismail A, Hamid M. Inhibitory properties of Ficus deltoidea on α-glucosidase activity. Research Journal of Medicinal Plant 2010; 4(2):61-75. 7. Adam Z, Khamis S, Ismail A, Hamid M. Ficus deltoidea: A potential alternative medicine for diabetes mellitus. Evidence-Based Complementary and Alternative Medicine 2012; Article ID: 632763:12 8. Oh M-J, Hamid AM, Ngadiran S, Seo Y-K, Sarmidi MR Park CS. Ficus deltoidea (Mas cotek) extract exerted anti-melanogenic activity by preventing tyrosinase activity in vitro and by suppressing tyrosinase gene expression in B16F1 melanoma cells. Arch. Dermatol. Res 2011; 303:161-170. 9. Hasham R, Choi HK, Sarmidi MR, Park CS. Protective effects of a Ficus deltoidea (Mas cotek) extract against UVB-induced photoageing in skin cells. Biotechnology and Bioprocess Engineering 2013; 18:185-193. 10. Corner, EJH. The complex of Ficus deltoidea; a recent invasion of the Sunda shelf. Phil. Trans. R. Soc. Lond 1969; 256:281-317. 11. Mohd KS, Azemin A, Hamil MSR, Abu Bakar AR, Dharmaraj S, Hamdan MR, et al. Application of HPTLC and FTIR profiling coupled with chemometrics for the differentiation of the varieties of Ficus deltoidea Jack. Asian Journal of Pharmaceutical and Clinical Research 2014; 7(5): 110-116. 12. Adam Z, Hamid M, Ismail A, Khamis S. Effect of Ficus deltoidea aqueous extract on blood glucose level in normal and mild diabetic rats. Jurnal Sains Kesihatan Malaysia 2007; 5(2): 9-16. 13. Syed Aris SR, Mustafa S, Ahmat N, Mohd Jaafar F and Ahmad R. Phenolic content and antioxidant activity of fruits of Ficus deltoidea var. angustifolia sp. The Malaysian Journal of Analytical Sciences 2009; 13(2): 146-150. 14. Khairi HM, Afifah MYN, Somchlt MN and Moin S. Anti-inflammatory properties of aqueous fruit extract of Ficus deltoidea Jack var. angustifolia (Miq.) Corner. Medicinal and Aromatic Plants Seminar (MAPS 2010) August 3– 4 2010 15. Bunawan H, Mat Amin N, Bunawan SN, Baharum SN and Mohd Noor N. Ficus deltoidea: A review on Its Phytochemical Pharmacological Importance. Evidence-Based Complementary and Alternative Medicine 2014; 8 16. Misbah H, Abdul Aziz A and Aminudin N. Antidiabetic and antioxidant properties of Ficus deltoidea fruit extracts and fractions. BMC Complementary & Alternative Medicine 2013; 13:118. 17. Aminudin N, Sin CY, Chee ES, Nee KI, Renxin L. Blood glucose lowering effect of Ficus deltoidea aqueous extract. Malaysian Journal of Science 2007; 26 (1):73-78. 18. Dzolin S, Aris SSR, Ahmad R. and Mat Zain M. Radical scavenging and neurotoxicity of four varieties of Ficus deltoidea. International Conference on Science and Social Research (CSSR). December 5-7 2010, Kuala Lumpur, Malaysia 19. Mayur B, Sandesh S, Shruti S. and Sung-Yum S. Antioxidant and α-glucosidase inhibitory properties of Carpesium abrotanoides L. Journal of Medicinal Plants Research 2010; 4(15): 1547-1553. 20. Marston A and Hostettmann K. Separation and Quantification of Flavonoids. In: Andersen Ø. M. and Markham K. R., editor. Flavonoids: chemistry, biochemistry and applications. London (NY): CRC Press Taylor & Francis Group; 2006. p. 1-36 21. Bougatef A, Hajji M, Balti R, Lassoued I, Triki-Ellouz Y. and Nasri M. Antioxidant and free radicalscavenging activities of smooth hound (Mustelus mustelus) muscle protein hydrolysates obtained by gastroinstenal proteases. Food Chemistry 2009; 114: 1198-1205. 22. Shimada K, Fujikawa K, Yahara K and Nakamura T. Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion. Journal of Agriculture and Food Chemistry 1992; 40: 945-948. 23. Farsi E, Shafaei A, Yee Hor S, Khadeer Ahamed BM, Yam MF, Attitalla IH, Asmawi, MZ, and Ismail Z. Correlation between enzymes inhibitory effects and antioxidant activities of standardized fractions of methanolic extract obtained from Ficus deltoidea leaves. African Journal of Biotechnology. 2011;10(67): 15184-15194. 24. Van de Laar FA, Lucassen PL, Akkermans RP, van de Lisdonk EH, Rutten GE and van Weel C. Α-Glucosidase inhibitors for patients with type 2 diabetes. Diabetes Care 2005; 28: 166-175. 25. Kalra S. Alpha glucosidase inhibitors. J. Pak. Med. Assoc. 214;64(4): 474-476. 26. Cheng AYY and Fantus GI. Oral antihyperglycemic therapy for type 2 diabetes mellitus. Canadian Medical Association 2005; 172(2):213-226. |
| spellingShingle | Comparison of chemical profile and biological activities of different plant parts of Ficus deltoidea Jack var. trengganuensis |
| summary | Ficus deltoidea var. Trengganuensis (FDT) is one of the variety of a highly potential herbs, Ficus deltoidea Jack. This herb has pharmacologically been shown to possess numerous biological activities. Commonly, only leaves have been used medicinally. In order to assess whether other part such as fig and stem can also be used for medicinal purposes, chemical profile and biological activities were compared. Samples that consist of leaves, figs and stems were collected from four locations in Trengganu state, east coast of Peninsular Malaysia. Thin layer chromatography (TLC) and Fourier transform infrared (FTIR) were used to assess the chemical profile. Two compounds, vitexin and isovitexin were used as authentication marker of FDT. A good separation of the chemical components and marker in all sample with distinct spots observed on fig TLC chromatogram at the solvent system of ethyl acetate: formic acid (0.1%): methanol (4:6:2 v/v/v). FTIR fingerprints also exhibit different profile for fig, stem and leaf extract. Principle component analysis on FTIR data revealed that figs from four locations clustered into one group in positive PC2 quadrant suggest that fig has specific constituents, which discriminate them from leaf and stem. Biological activities were assessed by 2, 2-diphenyl-1- picrylhydrazyl (DPPH) inhibition and α-glucosidase inhibition assays. Comparison between plant parts discovered that figs from all locations have the highest inhibition on both activities compared to leaves and stems. Finding from this study revealed that figs of FDT could also be consumed for therapeutic purposes in addition to the leaves. |
| title | Comparison of chemical profile and biological activities of different plant parts of Ficus deltoidea Jack var. trengganuensis |
| title_full | Comparison of chemical profile and biological activities of different plant parts of Ficus deltoidea Jack var. trengganuensis |
| title_fullStr | Comparison of chemical profile and biological activities of different plant parts of Ficus deltoidea Jack var. trengganuensis |
| title_full_unstemmed | Comparison of chemical profile and biological activities of different plant parts of Ficus deltoidea Jack var. trengganuensis |
| title_short | Comparison of chemical profile and biological activities of different plant parts of Ficus deltoidea Jack var. trengganuensis |
| title_sort | comparison of chemical profile and biological activities of different plant parts of ficus deltoidea jack var. trengganuensis |