Synergistic Molecular Effect of BDNF, ApoE and MTHFR in inducing Depression in Alzheimer’s Disease

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spelling 11469 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=11469 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf 2 1.6 Adobe Acrobat Pro DC 20 Paper Capture Plug-in like Gecko) Chrome/71.0.3578.98 Safari/537.36 Mozilla/5.0 (Windows NT 6.3; Win64; x64) AppleWebKit/537.36 (KHTML 2019-01-27 03:29:57 5714-01-FH02-FP-19-24384.pdf UniSZA Private Access Synergistic Molecular Effect of BDNF, ApoE and MTHFR in inducing Depression in Alzheimer’s Disease Research Journal of Pharmacy and Technology Alzheimer’s disease is genetically and pathophysiologically linked to depression. Various studies have been formulated on AD patients with depression and AD patients without depression. Genes like BDNF, ApoE and MTHFR have a significant role in depressed individuals causing the development of Alzheimer’s disease. The frequency of each gene marks the onset of Alzheimer’s disease. Single Nucleotide Polymorphisms in each specific gene show the increased risks of developing Alzheimer’s disease in depressed individuals. Amyloid Senile plaques and neurofibrillary tangles are caused more often in a depressed individual leading to AD. Development of antidepressants may lead to the correction and diminishing of AD in depressed individuals. 11 10 4317-4323
spellingShingle Synergistic Molecular Effect of BDNF, ApoE and MTHFR in inducing Depression in Alzheimer’s Disease
summary Alzheimer’s disease is genetically and pathophysiologically linked to depression. Various studies have been formulated on AD patients with depression and AD patients without depression. Genes like BDNF, ApoE and MTHFR have a significant role in depressed individuals causing the development of Alzheimer’s disease. The frequency of each gene marks the onset of Alzheimer’s disease. Single Nucleotide Polymorphisms in each specific gene show the increased risks of developing Alzheimer’s disease in depressed individuals. Amyloid Senile plaques and neurofibrillary tangles are caused more often in a depressed individual leading to AD. Development of antidepressants may lead to the correction and diminishing of AD in depressed individuals.
title Synergistic Molecular Effect of BDNF, ApoE and MTHFR in inducing Depression in Alzheimer’s Disease
title_full Synergistic Molecular Effect of BDNF, ApoE and MTHFR in inducing Depression in Alzheimer’s Disease
title_fullStr Synergistic Molecular Effect of BDNF, ApoE and MTHFR in inducing Depression in Alzheimer’s Disease
title_full_unstemmed Synergistic Molecular Effect of BDNF, ApoE and MTHFR in inducing Depression in Alzheimer’s Disease
title_short Synergistic Molecular Effect of BDNF, ApoE and MTHFR in inducing Depression in Alzheimer’s Disease
title_sort synergistic molecular effect of bdnf, apoe and mthfr in inducing depression in alzheimer’s disease