A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors
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| date | 2014-12-10 15:24:30 |
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| id | 11351 |
| institution | UniSZA |
| internalnotes | Adedeji WA, Ibrahem WA, Fehintola FA. Attitude and Practice of Doctors toward Adverse Drug Reactions (ADRs) Reporting In A Nigerian Tertiary Health Facility. Ann Ibd Pg Med, 2013; 1(2): 77-80. Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111063/pdf/AIPM-11-77.pdf (Accessed on 10/7/2014) Adhikary J, Bhandare B, Adarsh E, Satyanarayana V. A Study to Assess Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting among Physicians in a Tertiary Care Hospital. Journal of Evolution of Medical and Dental Sciences, 2013: 2 (9): 1027- 1034. Available from http://www.jemds.com/data_pdf/1_jyothirmayA%20STUDY%20TO%20ASSESS%20KNOWLEDGE.pdf (Accessed 10/8/2014) Agarwal R, Daher AM, Ismail NM. Knowledge, Practices and Attitudes Towards Adverse Drug Reaction Reporting by Private Practitioners from Klang Valley in Malaysia. Malays J Med Sci, 2013; 20(2): 52-61. Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744000/pdf/mjms-20-2-052.pdf (Accessed 10/8/2014) Aithal S, Hooli TV, Varun HV. Knowledge and Attitude about Adverse Drug Reaction Reporting among Doctors at a Tertiary Care Hospital. International Journal of Pharma & Bio Sciences, 2014; 5 (1): 108-113. Available from http://www.ijpbs.net/cms/php/upload/2976_pdf.pdf (Accessed 10/8/2014) Awodele O, Akinyede A, Adeyemi OA, Awodele DF. Pharmacovigilance amongst doctors in private hospitals in Lagos West Senatorial District, Nigeria. Int J Risk Saf Med, 2011; 23 (4): 217-226. Backstrom M, Mjorndal T. A small economic inducement to stimulate increased reporting of adverse drug reactions—a way of dealing with an old problem? Eur J Clin Pharmacol, 2006; 62: 381-385. Available from http://download.springer.com/static/pdf/527/art%253A10.1007%252Fs002 28-005-0072-0.pdf?auth66=1410888303_9c50afa1bcdb81d31e9a9e6aeda2ba3e&ext=.pdf (Accessed 10/7/2014) Bello SO, Umar MT. Knowledge and attitudes of physicians relating to reporting of adverse drug reactions in Sokoto, North-Western Nigeria. Annals of African Medicine. 10 (1); 2011: 13-18. Available from http://www.researchgate.net/publication/49826701_Knowledge_and_attitu des_of_physicians_relating_to_reporting_of_adverse_drug_reactions_in_Sokoto_north-western_Nigeria (Accessed 10/8/2014) Bisht M,Singh S, Dhasmana DC. Effect of Educational Intervention on Adverse Drug Reporting by Physicians: A Cross-Sectional Study. ISRN Pharmacology, 2014; Article ID 259476. Available from file:///C:/Users/User/Downloads/259476.pdf (Accessed 11/8/2014) Chatterjee S, Lyle N, Ghosh S. A survey of the knowledge, attitude and practice of adverse drug reaction reporting by clinicians in eastern India. Drug Saf, 2006; 29(7): 641-642. (Accessed 11/8/2014) Chopra D, Wardhan N, Rehan HS. Knowledge, attitude and practices associated with adverse drug reaction reporting amongst doctors in a teaching hospital. The International Journal of Risk & Safety In Medicine, 2011; 23(4): 227-232. Available from http://web.b.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=9&sid=00746 7f1-7730-4558-a2f0-abb089b9b06c%40sessionmgr112&hid=128 (Accessed 11/8/2014) Desai CK, Iyer G, Panchal J, Shah S, Dikshit RK. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspect Clin Res, 2011; 2 (4): 129-136. Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227330/ (Accessed on 1/9/2014) Edward IR, Aronson JK. Adverse drug reactions: definitions, diagnosis and management. Lancet, 2000; 356(9237): 1255-1259. Available from http://www.scribd.com/doc/22293073/Adverse-DrugReactions-Definitions-Diagnosis-And-Management (Accessed 12/8/2014) Farcas, A, Macavei C, Bojita M. Physicians’ attitude towards voluntary reporting of adverse drug reactions. FARMACIA, 2008; 56 (5): 563-570. http://www.revistafarmacia.ro/20085/issue52008art12.doc (Accessed 12/8/2014) Gray J. Bill would force drug makers to give customers data on risk. The New York Times. July 25, 1996: A11. Gupta P, Udupa A. Adverse Drug Reaction Reporting and Pharmacovigilance: Knowledge, Attitudes and Perceptions amongst Resident Doctors. J Pharm Sci Res, 2011; 3(2): 1064-1069. Available from http://www.jpsr.pharmainfo.in/Documents/Volumes/Vol3Issue02/jpsr%2003110205.pdf (Accessed 12/8/2014) Harmark L, van Grootheest AC. Pharmacovigilance: methods, recent developments and future perspectives. Eur J Clin Pharmacol, 2008; 64:743–752. Available from http://download.springer.com/static/pdf/836/art%253A10.1007%252Fs00228-008-0475-9.pdf?auth66=1410972179_7730691fe6dc6eed698d8e4eb37d978d&ext=. pdf Herdeiro MT, Figueiras A, Polonia J, Gestal-Otero JJ. Physicians’ Attitudes and Adverse Drug Reaction Reporting: A Case-Control Study in Portugal. Drug Safety, 2005; 28 (9): 825-833. Available from http://phdtree.org/pdf/16296648-physicians-attitudes-and-adversedrug-reaction-reporting-a-case-control-study-in-portugal/ http://www.lareb.nl/LarebCorporateWebsite/media/publicaties/2009-3_DS_ADR_GP.pdf (Accessed 10/8/2014) Iffat W, Shakeel S, Rahim N, Anjum F, Neesar S, Ghayas S. Pakistani physicians’ knowledge and attitude towards reporting adverse drug reactions. African Journal of Pharmacy and Pharmacology, 2014; 8 (14): 379-385. Available from http://www.academicjournals.org/article/article1398412633_Iffat%20et%20al.pdf (Accessed 10/8/2014) International Society of Drug Bulletins (ISDB), Berlin Declaration on Pharmacovigilance, January, 2005. Available from http://www.isdbweb.org/documents/uploads/Declaration/Berlin_Declaration_Berlin%20Engl.pdf (Accessed 11/8/2014) John LJ, Arifulla M, Cheriathu J, Sreedharan J. Reporting of Adverse Drug Reactions: a study among Clinicians. Journal of Applied Pharmaceutical Science, 2012; 2 (6): 135-139. Available from http://www.japsonline.com/admin/php/uploads/518_pdf.pdf (Accessed 10/8/2014) Kachhadiya R, Kumar A, Bhatia RK. Prevalence of medication errors across the world. International Journal of Pharmaceutical Research, 2009; 1(3):21-34. Available from http://www.ijpronline.com/ViewArticleDetail.aspx?ID=36 (Accessed 10/8/2014) Kamtane RA, Jayawardhani V. Knowledge, attitude and perception of physicians towards adverse drug reaction (ADR) reporting: a pharmacoepidemiological study. Asian J Pharm Clin Res, 2012; 5(3): 210- 214. Available from http://www.ajpcr.com/Vol5Suppl3/1231.pdf (Accessed 10/8/2014) Khan SA, Goyal C, Chandel N, Rafi M. Knowledge, attitudes, and practice of doctors to adverse drug reaction reporting in a teaching hospital in India: An observational study. Journal of Natural Science, Biology, and Medicine, 2013; 4(1): 191-196. Available from (Accessed 11/8/2014) Kharkar M, Bowalekar S. Knowledge, attitude and perception/practices (KAP) of medical practitioners in India towards adverse drug reaction (ADR) reporting. Perspect Clin Res, 2012; 3(3): 90-94. Kiran LJ, Shivashankaramurthy K G, Bhooma S, Dinakar Kr. Adverse drug reaction reporting among clinicians in a teaching hospital in South Karnataka. Sch Journ App Med Sci, 2014; 2(1D):399-403. Available from http://saspublisher.com/wp-content/uploads/2014/03/SJAMS21D399-403.pdf Kohn L, Corrigan J, Donalson M. Eds to err is Human: Building safer Health System. Washington, DC: Institute of Medicine. 2000. Available from http://neurosurgery.ucsf.edu/tl_files/NS_Main/QI/IOM_To%20Err%20is%20Human.pdf (Accessed 11/8/2014) Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients. A meta-analysis of prospective studies. JAMA, 1998; 279(15): 1200-1205. Available from http://www.ncbi.nlm.nih.gov/pubmed/9555760 (Accessed 10/8/2014) Oshikoya KA, Awobusuyi JO. Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria. BMC Clin Pharmacol, 2009; 9 (14). Available from http://www.biomedcentral.com/content/pdf/1472-6904-9-14.pdf (Accessed on 1/9/2014) Passier A, Napel MT, van Grootheest K, van Puijenbroek E. Reporting of Adverse Drug Reactions by General Practitioners. Drug Saf, 2009; 32 (10): 851-858. Available from http://link.springer.com/article/10.2165%2F11314490-000000000-00000 (Accessed on 30/8/2014) Patel A, Ganguly B. Analysis of Dose Calculation of Medicines Prescribed in Pediatric Age Group. International Journal of Pharmaceutical Research, 2010; 2(4): 21-25. Paveliu MS, Bengea-Luculescu S, Toma M, Paveliu SF. Perception on Adverse Drug Reaction Reporting by Physicians Working in Southern Romania. Journal of Clinical Medicine, 2013; 8(1): 17-25. Available from http://www.maedica.org/articles/2013/1/2013_Vol8%2811%29_No1_pg17-25.pdf (Accessed 11/8/2014) Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. potential role of pharmacogenomics in reducing adverse dug reaction. JAMA, 2001; 286 (18): 2270- 2279. Available from http://jama.jamanetwork.com/bypdf (Accessed 10/8/2014) Pimpalkhute SA, Jaiswal KM, Sontakke SD, Bajait CS, Gaikwad A. Evaluation of awareness about pharmacovigilance and adverse drug reaction monitoring in resident doctors of a tertiary care teaching hospital. Indian J Med Sci, 20121; 66 (3 & 4): 55-61. Available from http://web.b.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=5&sid=00746 7f1-7730-4558-a2f0-abb089b9b06c%40sessionmgr112&hid=128 Ramesh M, Parthasarathi G. Adverse drug reactions reporting: attitudes and perceptions of medical practitioners. Asian J Pharm Clin Res, 2009; 2 (2): 10-14. Available from http://www.ajpcr.com/Vol2Issue2/184.pdf (Accessed 10/8/2014) Rishi RK, Patel RK, Bhandari A. Opinion of physicians towards Adverse Drug Reaction reporting Result of pilot study. Journal of Community Nutrition and Health, 2012b; 1 (1): 25-29. Available from URL:http://jcnh.in/download/isse1/6.%20Rakesh.pdf (Accessed 10/8/2014) Rishi RK, Patel RK, Bhandari A. Under Reporting of ADRs by Medical Practitioners in India - Results of Pilot Study. Advances in Pharmacoepidemiol and Drug Saf, 2012a; 1 (3): 1-3. Available from http://omicsgroup.org/journals/under-reporting-of-adrs-by-medicalpractitioners-in-india-results-of-pilot-study-2167-1052.1000112.pdf (Accessed 10/8/2014) Salam A, Haque M, Islam MZ, Rahman NIA, Helali AM, Muda TFMBT, Yousuf R, Yesmin F, Rahman Z, Alattraqchi AG. Addressing rational prescribers through pharmacology and therapeutics course work of MBBS syllabus in Bangladesh. International Research Journal Pharmacy, 2013; 4 (7): 60-63. Available from http://dx.doi.org/10.7897/2230- 8407.04713/pdf (Accessed 10/8/2014) Sanghavi DR, Dhande PP, Pandit VA. Perception of pharmacovigilance among doctors in a tertiary care hospital: Influence of an interventional lecture. Int J Risk Saf Med, 2013; 25 (4): 197–204. Available from http://web.b.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=6&sid=00746 7f1-7730-4558-a2f0-abb089b9b06c%40sessionmgr112&hid=128 (Accessed 10/8/2014) Shailesh N, Ranjana K, Kumar VS, Satish B. Impact of Educational Intervention on Knowledge, Attitude and Practice of Pharmacovigilance among Medical Graduates of Rural Tertiary Care Teaching Hospital Of Central India. Mintage journal of Pharmaceutical & Medical Sciences, 2013; 2(2): 51-54. Available from http://mintagejournals.com/index_htm_files/123.pdf Tabali M, Jeschke E, Bockelbrink A, Witt CM, Willich SN, Ostermann T, Matthes H. Educational intervention to improve physician reporting of adverse drug reactions (ADRs) in a primary care setting in complementary and alternative medicine. BMC Public Health, 2009; 9(274). Available from http://www.biomedcentral.com/content/pdf/1471- 2458-9-274.pdf (Accessed 10/7/2014) Talbot JC, Nilsson BS. Pharmacovigilance in the pharmaceutical industry. Br J Clin Pharmacol, 1998; 45(5): 427-31. Available from http://onlinelibrary.wiley.com/doi/10.1046/j.1365- 2125.1998.00713.x/pdf (Accessed 10/7/2014) Thomas TM, Udaykumar P, Scandashree K. Knowledge, attitude and practice of adverse drug reaction reporting among doctors in a tertiary health care centre in South India. Int J Pharmacol Clin Sci, 2013; 2(3): 82-88. Available from http://www.ijpcs.net/uploads/1/0/3/4/10341868/ijpcs-0023-2013.pdf Upadhyaya P, Seth V, Moghe VV, Sharma M, Ahmed M. Knowledge of adverse drug reaction reporting in first year postgraduate doctors in a medical college. Ther Clin Risk Manag, 2012; 8: 307–312. Available from file:///C:/Users/User/Downloads/TCRM-31482- knowledge-of-adverse-drug-reaction-reporting-in-first-year-p_061812.pdf (Accessed 10/7/2014) van Grootheest K, de Jong-van D. Patients’ role in reporting adverse drug reactions. Expert Opin Drug Saf, 2004; 3(4): 363-368. van Grootheest K, Olsson S, Couper M. Pharmacists’ role in reporting adverse drug reactions in an international perspective. Pharmacoepidemiol Drug Saf, 2004; 13(7):457-464. Available from http://onlinelibrary.wiley.com/doi/10.1002/pds.897/abstract;jsessionid=FE A1D0E08859B298C5701A963C98D8B5.f01t03 (Accessed on 1/7/2014) World Health Organization (WHO) Definitions. WHO International Drug Monitoring: The role of national centres: Tech Rep Ser.1972 no. 498. Available from http://www.who.int/medicines/areas/quality_safety/safety_efficacy/trainin gcourses/definitions.pdf (Accessed 10/7/2014) World Health Organization (WHO). International Drug Monitoring: The Role of Hospital; Geneva, Switzerland: WHO; 1969. Technical Report Series No. 425. Available from http://whqlibdoc.who.int/trs/WHO_TRS_425.pdf (Accessed 10/7/2014) World Health Organization (WHO). Safety of Medicines. A guide to detecting and reporting adverse drug reactions. Why health professionals need to take action. Geneva World Health Organization. 2002. Available from http://whqlibdoc.who.int/hq/2002/WHO_EDM_QSM_2002.2.pdf (Accessed 10/7/2014) |
| originalfilename | 5574-01-FH02-FPSK-14-02088.jpg |
| person | UniSZA Unisza unisza |
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| resourceurl | https://intelek.unisza.edu.my/intelek/pages/view.php?ref=11351 |
| spelling | 11351 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=11351 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal UniSZA Unisza unisza image/jpeg inches 96 96 79 79 786 1410 2014-12-10 15:24:30 1410x786 5574-01-FH02-FPSK-14-02088.jpg UniSZA Private Access A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors Journal of Applied Pharmaceutical Science Background: Adverse drug reactions (ADRs) have been making headlines because of life threatening issues. ADRs are always underreported and still the major public health problem. Spontaneous reporting system has remained the most significant method for safeguarding patients’ lives. Objectives: Is to examine and analyse the various pharmacovigilance (PV) studies conducted among doctors and to make recommendations for future research. Study Selection: 32 studies covered from 2004 to 2014 were selected. Data Sources: Four electronic data-bases including Science-Direct, Springer-Link, PubMed and MEDLINE were used to obtain 129 relevant publications using HotBot, FreeFullPDF, and Google Scholar as search engines. Data Extraction: Studies conducted on doctors were selected covering research from ten countries. Inclusion Criteria: Only studies done from 2004 to 2014 were included, KAP studies done on ADRs and pharmacovigilance among doctors were selected. Exclusion criteria: All studies done before 2004 and studies done on general public KAP were excluded; similarly, studies conducted on healthcare professionals in general were excluded; also studies done on adverse drug event (ADE) reporting were excluded. The study was conducted from April to August, 2014. Data Synthesis: Knowledge, attitude and practice (KAP) regarding ADRs reporting by doctors were poor. Longitudinal study involving educational intervention and training through workshops and seminars were found to be effective in improving doctors’ knowledge and attitude. Conclusion: There is urgent need to improve knowledge, awareness and practice of doctors on pharmacovigilance. It is imperative for WHO and national pharmacovigilance centres to take proactive measures to curve the menace of ADRs in order to safeguard the patients’ lives. The curriculum of all health and health related schools should be restructured with respect to pharmacovigilance without any delay and hesitation. 4 10 117-127 Adedeji WA, Ibrahem WA, Fehintola FA. Attitude and Practice of Doctors toward Adverse Drug Reactions (ADRs) Reporting In A Nigerian Tertiary Health Facility. Ann Ibd Pg Med, 2013; 1(2): 77-80. Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111063/pdf/AIPM-11-77.pdf (Accessed on 10/7/2014) Adhikary J, Bhandare B, Adarsh E, Satyanarayana V. A Study to Assess Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting among Physicians in a Tertiary Care Hospital. Journal of Evolution of Medical and Dental Sciences, 2013: 2 (9): 1027- 1034. Available from http://www.jemds.com/data_pdf/1_jyothirmayA%20STUDY%20TO%20ASSESS%20KNOWLEDGE.pdf (Accessed 10/8/2014) Agarwal R, Daher AM, Ismail NM. Knowledge, Practices and Attitudes Towards Adverse Drug Reaction Reporting by Private Practitioners from Klang Valley in Malaysia. Malays J Med Sci, 2013; 20(2): 52-61. Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744000/pdf/mjms-20-2-052.pdf (Accessed 10/8/2014) Aithal S, Hooli TV, Varun HV. Knowledge and Attitude about Adverse Drug Reaction Reporting among Doctors at a Tertiary Care Hospital. International Journal of Pharma & Bio Sciences, 2014; 5 (1): 108-113. Available from http://www.ijpbs.net/cms/php/upload/2976_pdf.pdf (Accessed 10/8/2014) Awodele O, Akinyede A, Adeyemi OA, Awodele DF. Pharmacovigilance amongst doctors in private hospitals in Lagos West Senatorial District, Nigeria. Int J Risk Saf Med, 2011; 23 (4): 217-226. Backstrom M, Mjorndal T. A small economic inducement to stimulate increased reporting of adverse drug reactions—a way of dealing with an old problem? Eur J Clin Pharmacol, 2006; 62: 381-385. Available from http://download.springer.com/static/pdf/527/art%253A10.1007%252Fs002 28-005-0072-0.pdf?auth66=1410888303_9c50afa1bcdb81d31e9a9e6aeda2ba3e&ext=.pdf (Accessed 10/7/2014) Bello SO, Umar MT. Knowledge and attitudes of physicians relating to reporting of adverse drug reactions in Sokoto, North-Western Nigeria. Annals of African Medicine. 10 (1); 2011: 13-18. Available from http://www.researchgate.net/publication/49826701_Knowledge_and_attitu des_of_physicians_relating_to_reporting_of_adverse_drug_reactions_in_Sokoto_north-western_Nigeria (Accessed 10/8/2014) Bisht M,Singh S, Dhasmana DC. Effect of Educational Intervention on Adverse Drug Reporting by Physicians: A Cross-Sectional Study. ISRN Pharmacology, 2014; Article ID 259476. Available from file:///C:/Users/User/Downloads/259476.pdf (Accessed 11/8/2014) Chatterjee S, Lyle N, Ghosh S. A survey of the knowledge, attitude and practice of adverse drug reaction reporting by clinicians in eastern India. Drug Saf, 2006; 29(7): 641-642. (Accessed 11/8/2014) Chopra D, Wardhan N, Rehan HS. Knowledge, attitude and practices associated with adverse drug reaction reporting amongst doctors in a teaching hospital. The International Journal of Risk & Safety In Medicine, 2011; 23(4): 227-232. Available from http://web.b.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=9&sid=00746 7f1-7730-4558-a2f0-abb089b9b06c%40sessionmgr112&hid=128 (Accessed 11/8/2014) Desai CK, Iyer G, Panchal J, Shah S, Dikshit RK. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspect Clin Res, 2011; 2 (4): 129-136. Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227330/ (Accessed on 1/9/2014) Edward IR, Aronson JK. Adverse drug reactions: definitions, diagnosis and management. Lancet, 2000; 356(9237): 1255-1259. Available from http://www.scribd.com/doc/22293073/Adverse-DrugReactions-Definitions-Diagnosis-And-Management (Accessed 12/8/2014) Farcas, A, Macavei C, Bojita M. Physicians’ attitude towards voluntary reporting of adverse drug reactions. FARMACIA, 2008; 56 (5): 563-570. http://www.revistafarmacia.ro/20085/issue52008art12.doc (Accessed 12/8/2014) Gray J. Bill would force drug makers to give customers data on risk. The New York Times. July 25, 1996: A11. Gupta P, Udupa A. Adverse Drug Reaction Reporting and Pharmacovigilance: Knowledge, Attitudes and Perceptions amongst Resident Doctors. J Pharm Sci Res, 2011; 3(2): 1064-1069. Available from http://www.jpsr.pharmainfo.in/Documents/Volumes/Vol3Issue02/jpsr%2003110205.pdf (Accessed 12/8/2014) Harmark L, van Grootheest AC. Pharmacovigilance: methods, recent developments and future perspectives. Eur J Clin Pharmacol, 2008; 64:743–752. Available from http://download.springer.com/static/pdf/836/art%253A10.1007%252Fs00228-008-0475-9.pdf?auth66=1410972179_7730691fe6dc6eed698d8e4eb37d978d&ext=. pdf Herdeiro MT, Figueiras A, Polonia J, Gestal-Otero JJ. Physicians’ Attitudes and Adverse Drug Reaction Reporting: A Case-Control Study in Portugal. Drug Safety, 2005; 28 (9): 825-833. Available from http://phdtree.org/pdf/16296648-physicians-attitudes-and-adversedrug-reaction-reporting-a-case-control-study-in-portugal/ http://www.lareb.nl/LarebCorporateWebsite/media/publicaties/2009-3_DS_ADR_GP.pdf (Accessed 10/8/2014) Iffat W, Shakeel S, Rahim N, Anjum F, Neesar S, Ghayas S. Pakistani physicians’ knowledge and attitude towards reporting adverse drug reactions. African Journal of Pharmacy and Pharmacology, 2014; 8 (14): 379-385. Available from http://www.academicjournals.org/article/article1398412633_Iffat%20et%20al.pdf (Accessed 10/8/2014) International Society of Drug Bulletins (ISDB), Berlin Declaration on Pharmacovigilance, January, 2005. Available from http://www.isdbweb.org/documents/uploads/Declaration/Berlin_Declaration_Berlin%20Engl.pdf (Accessed 11/8/2014) John LJ, Arifulla M, Cheriathu J, Sreedharan J. Reporting of Adverse Drug Reactions: a study among Clinicians. Journal of Applied Pharmaceutical Science, 2012; 2 (6): 135-139. Available from http://www.japsonline.com/admin/php/uploads/518_pdf.pdf (Accessed 10/8/2014) Kachhadiya R, Kumar A, Bhatia RK. Prevalence of medication errors across the world. International Journal of Pharmaceutical Research, 2009; 1(3):21-34. Available from http://www.ijpronline.com/ViewArticleDetail.aspx?ID=36 (Accessed 10/8/2014) Kamtane RA, Jayawardhani V. Knowledge, attitude and perception of physicians towards adverse drug reaction (ADR) reporting: a pharmacoepidemiological study. Asian J Pharm Clin Res, 2012; 5(3): 210- 214. Available from http://www.ajpcr.com/Vol5Suppl3/1231.pdf (Accessed 10/8/2014) Khan SA, Goyal C, Chandel N, Rafi M. Knowledge, attitudes, and practice of doctors to adverse drug reaction reporting in a teaching hospital in India: An observational study. Journal of Natural Science, Biology, and Medicine, 2013; 4(1): 191-196. Available from (Accessed 11/8/2014) Kharkar M, Bowalekar S. Knowledge, attitude and perception/practices (KAP) of medical practitioners in India towards adverse drug reaction (ADR) reporting. Perspect Clin Res, 2012; 3(3): 90-94. Kiran LJ, Shivashankaramurthy K G, Bhooma S, Dinakar Kr. Adverse drug reaction reporting among clinicians in a teaching hospital in South Karnataka. Sch Journ App Med Sci, 2014; 2(1D):399-403. Available from http://saspublisher.com/wp-content/uploads/2014/03/SJAMS21D399-403.pdf Kohn L, Corrigan J, Donalson M. Eds to err is Human: Building safer Health System. Washington, DC: Institute of Medicine. 2000. Available from http://neurosurgery.ucsf.edu/tl_files/NS_Main/QI/IOM_To%20Err%20is%20Human.pdf (Accessed 11/8/2014) Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients. A meta-analysis of prospective studies. JAMA, 1998; 279(15): 1200-1205. Available from http://www.ncbi.nlm.nih.gov/pubmed/9555760 (Accessed 10/8/2014) Oshikoya KA, Awobusuyi JO. Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria. BMC Clin Pharmacol, 2009; 9 (14). Available from http://www.biomedcentral.com/content/pdf/1472-6904-9-14.pdf (Accessed on 1/9/2014) Passier A, Napel MT, van Grootheest K, van Puijenbroek E. Reporting of Adverse Drug Reactions by General Practitioners. Drug Saf, 2009; 32 (10): 851-858. Available from http://link.springer.com/article/10.2165%2F11314490-000000000-00000 (Accessed on 30/8/2014) Patel A, Ganguly B. Analysis of Dose Calculation of Medicines Prescribed in Pediatric Age Group. International Journal of Pharmaceutical Research, 2010; 2(4): 21-25. Paveliu MS, Bengea-Luculescu S, Toma M, Paveliu SF. Perception on Adverse Drug Reaction Reporting by Physicians Working in Southern Romania. Journal of Clinical Medicine, 2013; 8(1): 17-25. Available from http://www.maedica.org/articles/2013/1/2013_Vol8%2811%29_No1_pg17-25.pdf (Accessed 11/8/2014) Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. potential role of pharmacogenomics in reducing adverse dug reaction. JAMA, 2001; 286 (18): 2270- 2279. Available from http://jama.jamanetwork.com/bypdf (Accessed 10/8/2014) Pimpalkhute SA, Jaiswal KM, Sontakke SD, Bajait CS, Gaikwad A. Evaluation of awareness about pharmacovigilance and adverse drug reaction monitoring in resident doctors of a tertiary care teaching hospital. Indian J Med Sci, 20121; 66 (3 & 4): 55-61. Available from http://web.b.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=5&sid=00746 7f1-7730-4558-a2f0-abb089b9b06c%40sessionmgr112&hid=128 Ramesh M, Parthasarathi G. Adverse drug reactions reporting: attitudes and perceptions of medical practitioners. Asian J Pharm Clin Res, 2009; 2 (2): 10-14. Available from http://www.ajpcr.com/Vol2Issue2/184.pdf (Accessed 10/8/2014) Rishi RK, Patel RK, Bhandari A. Opinion of physicians towards Adverse Drug Reaction reporting Result of pilot study. Journal of Community Nutrition and Health, 2012b; 1 (1): 25-29. Available from URL:http://jcnh.in/download/isse1/6.%20Rakesh.pdf (Accessed 10/8/2014) Rishi RK, Patel RK, Bhandari A. Under Reporting of ADRs by Medical Practitioners in India - Results of Pilot Study. 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| spellingShingle | A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors |
| summary | Background: Adverse drug reactions (ADRs) have been making headlines because of life threatening issues. ADRs are always underreported and still the major public health problem. Spontaneous reporting system has remained the most significant method for safeguarding patients’ lives. Objectives: Is to examine and analyse the various pharmacovigilance (PV) studies conducted among doctors and to make recommendations for future research. Study Selection: 32 studies covered from 2004 to 2014 were selected. Data Sources: Four electronic data-bases including Science-Direct, Springer-Link, PubMed and MEDLINE were used to obtain 129 relevant publications using HotBot, FreeFullPDF, and Google Scholar as search engines. Data Extraction: Studies conducted on doctors were selected covering research from ten countries. Inclusion Criteria: Only studies done from 2004 to 2014 were included, KAP studies done on ADRs and pharmacovigilance among doctors were selected. Exclusion criteria: All studies done before 2004 and studies done on general public KAP were excluded; similarly, studies conducted on healthcare professionals in general were excluded; also studies done on adverse drug event (ADE) reporting were excluded. The study was conducted from April to August, 2014. Data Synthesis: Knowledge, attitude and practice (KAP) regarding ADRs reporting by doctors were poor. Longitudinal study involving educational intervention and training through workshops and seminars were found to be effective in improving doctors’ knowledge and attitude. Conclusion: There is urgent need to improve knowledge, awareness and practice of doctors on pharmacovigilance. It is imperative for WHO and national pharmacovigilance centres to take proactive measures to curve the menace of ADRs in order to safeguard the patients’ lives. The curriculum of all health and health related schools should be restructured with respect to pharmacovigilance without any delay and hesitation. |
| title | A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors |
| title_full | A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors |
| title_fullStr | A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors |
| title_full_unstemmed | A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors |
| title_short | A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors |
| title_sort | systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors |