| _version_ |
1860796938535829504
|
| building |
INTELEK Repository
|
| collection |
Online Access
|
| collectionurl |
https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
|
| date |
2015-03-13 11:03:24
|
| format |
Restricted Document
|
| id |
10755
|
| institution |
UniSZA
|
| originalfilename |
4877-01-FH02-FPSK-15-02853.pdf
|
| person |
Adobe InDesign CS2 (4.0.5)
|
| recordtype |
oai_dc
|
| resourceurl |
https://intelek.unisza.edu.my/intelek/pages/view.php?ref=10755
|
| spelling |
10755 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=10755 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf 10 1.6 Adobe Acrobat Pro DC 20 Paper Capture Plug-in Adobe InDesign CS2 (4.0.5) 2015-03-13 11:03:24 adobe:docid:indd:879a4894-aeac-11e1-8dce-bd1d4aaeaf50 4877-01-FH02-FPSK-15-02853.pdf UniSZA Private Access Vital roles of stem cells and biomaterials in skin tissue engineering World Journal Of Stem cells Tissue engineering essentially refers to technology for growing new human tissue and is distinct from regenerative medicine. Currently, pieces of skin are already being fabricated for clinical use and many other tissue types may be fabricated in the future. Tissue engineering was first defined in 1987 by the United States National Science Foundation which critically discussed the future targets of bioengineering research and its consequences. The principles of tissue engineering are to initiate cell cultures in vitro, grow them on scaffolds in situ and transplant the composite into a recipient in vivo. From the beginning, scaffolds have been necessary in tissue engineering applications. Regardless, the latest technology has redirected established approaches by omitting scaffolds. Currently, scientists from diverse research institutes are engineering skin without scaffolds. Due to their advantageous properties, stem cells have robustly transformed the tissue engineering field as part of an engineered bilayered skin substitute that will later be discussed in detail. Additionally, utilizing biomaterials or skin replacement products in skin tissue engineering as strategy to successfully direct cell proliferation and differentiation as well as to optimize the safety of handling during grafting is beneficial. This approach has also led to the cells’ application in developing the novel skin substitute that will be briefly explained in this review. 7 2 428-436
|
| spellingShingle |
Vital roles of stem cells and biomaterials in skin tissue engineering
|
| summary |
Tissue engineering essentially refers to technology for growing new human tissue and is distinct from regenerative medicine. Currently, pieces of skin are already being fabricated for clinical use and many other tissue types may be fabricated in the future. Tissue engineering was first defined in 1987 by the United States National Science Foundation which critically discussed the future targets of bioengineering research and its consequences. The principles of tissue engineering are to initiate cell cultures in vitro, grow them on scaffolds in situ and transplant the composite into a recipient in vivo. From the beginning, scaffolds have been necessary in tissue engineering applications. Regardless, the latest technology has redirected established approaches by omitting scaffolds. Currently, scientists from diverse research institutes are engineering skin without scaffolds. Due to their advantageous properties, stem cells have robustly transformed the tissue engineering field as part of an engineered bilayered skin substitute that will later be discussed in detail. Additionally, utilizing biomaterials or skin replacement products in skin tissue engineering as strategy to successfully direct cell proliferation and differentiation as well as to optimize the safety of handling during grafting is beneficial. This approach has also led to the cells’ application in developing the novel skin substitute that will be briefly explained in this review.
|
| title |
Vital roles of stem cells and biomaterials in skin tissue engineering
|
| title_full |
Vital roles of stem cells and biomaterials in skin tissue engineering
|
| title_fullStr |
Vital roles of stem cells and biomaterials in skin tissue engineering
|
| title_full_unstemmed |
Vital roles of stem cells and biomaterials in skin tissue engineering
|
| title_short |
Vital roles of stem cells and biomaterials in skin tissue engineering
|
| title_sort |
vital roles of stem cells and biomaterials in skin tissue engineering
|