The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia

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collectionurl https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
date 2014-10-21 17:32:05
format Restricted Document
id 10678
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originalfilename 4756-01-FH02-FPB-15-02862.pdf
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resourceurl https://intelek.unisza.edu.my/intelek/pages/view.php?ref=10678
spelling 10678 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=10678 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf 7 1.6 Adobe Acrobat Pro DC 20 Paper Capture Plug-in AH XSL Formatter V6.1 MR4 Lite for Windows (x64) : 6.1.9.14491 (2013/12/19 12:04JST) 2014-10-21 17:32:05 4756-01-FH02-FPB-15-02862.pdf UniSZA Private Access The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia Molecular Biomarkers & Diagnosis The purpose is to review the current knowledge and methods of determination of the free alpha hemoglobin with emphasis on its potential implications in patients with beta-thalassemia (β-thal).The severity of β-thal correlates with the extent of imbalance between α- and non-α-globin chains and the amount of the free alpha hemoglobin (free α- Hb) pool in the erythrocytes. To date, there is a lack of biomarkers that convey diagnostic and prognostic values in β-thal. Our ongoing research is aimed to evaluate the potential prognostic and diagnostic implications of free α-Hb to improve the care of patients with β-thal. Our ongoing research is aimed to quantify the free α-Hb for its potential prognostic and diagnostic implications towards improving the care of patients with various β-thal types in the years to come. 5 5 1-7 http://omicsonline.org/open-access/the-free-alphahemoglobin-
spellingShingle The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia
summary The purpose is to review the current knowledge and methods of determination of the free alpha hemoglobin with emphasis on its potential implications in patients with beta-thalassemia (β-thal).The severity of β-thal correlates with the extent of imbalance between α- and non-α-globin chains and the amount of the free alpha hemoglobin (free α- Hb) pool in the erythrocytes. To date, there is a lack of biomarkers that convey diagnostic and prognostic values in β-thal. Our ongoing research is aimed to evaluate the potential prognostic and diagnostic implications of free α-Hb to improve the care of patients with β-thal. Our ongoing research is aimed to quantify the free α-Hb for its potential prognostic and diagnostic implications towards improving the care of patients with various β-thal types in the years to come.
title The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia
title_full The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia
title_fullStr The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia
title_full_unstemmed The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia
title_short The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia
title_sort free alpha-hemoglobin: a promising biomarker for β-thalassemia