Study On Antioxidant Capacity And Anticancer Activity Of Bismillah Leaf ( Vernoniaamygdalina )
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| collectionurl | https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 |
| date | 2014-08-12 05:13:34 |
| format | Restricted Document |
| id | 10601 |
| institution | UniSZA |
| originalfilename | 4650-01-FH02-FPSK-14-02079.pdf |
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| spelling | 10601 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=10601 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf 16 1.6 Adobe Acrobat Pro DC 20 Paper Capture Plug-in UniSZA Unisza unisza 2014-08-12 05:13:34 4650-01-FH02-FPSK-14-02079.pdf UniSZA Private Access Study On Antioxidant Capacity And Anticancer Activity Of Bismillah Leaf ( Vernoniaamygdalina ) World Journal of Pharmaceuticals research Vernoniaamygdalina is commonly called bitter leaf because of its bitter taste. The leaves may be consumed either as a vegetable (macerated leaves in soups) or aqueous extracts as tonics for the treatment of various illnesses. This study was carried out to evaluate antioxidant capacity of the methanol, chloroform and ethyl acetate extracts of V. Amygdalina and as antiproliferative agents in inhibiting the growth of human colon adenocarcinoma cell line (HT-29) and human breast adenocarcinoma cell line (MCF-7). It was found that ethyl acetate fraction have maximum amount of polyphenolics compounds (2.69 mg/g GAE in concentration 0.5 mg/mL); more effective than methanol and chloroform extract. This fraction also exhibited fairly good antioxidant activity with in both TBA (17.39% mg/g GAE) and FTC (12.65% mg/g GAE) methods. Antiproliferative study indicated that V. Amygdalina crude extract have great potential as antiproliferative compounds against various cancer cell lines and can significantly inhibit the growth of MCF-7 and HT-29 cancer cells. The methanol V. Amygdalina extract has a broad spectrum of activity by inhibiting the growth of MCF-7 and HT-29 cancer cells. 3 6 14-29 |
| spellingShingle | Study On Antioxidant Capacity And Anticancer Activity Of Bismillah Leaf ( Vernoniaamygdalina ) |
| summary | Vernoniaamygdalina is commonly called bitter leaf because of its bitter taste. The leaves may be consumed either as a vegetable (macerated leaves in soups) or aqueous extracts as tonics for the treatment of various illnesses. This study was carried out to evaluate antioxidant capacity of the methanol, chloroform and ethyl acetate extracts of V. Amygdalina and as antiproliferative agents in inhibiting the growth of human colon adenocarcinoma cell line (HT-29) and human breast adenocarcinoma cell line (MCF-7). It was found that ethyl acetate fraction have maximum amount of polyphenolics compounds (2.69 mg/g GAE in concentration 0.5 mg/mL); more effective than methanol and chloroform extract. This fraction also exhibited fairly good antioxidant activity with in both TBA (17.39% mg/g GAE) and FTC (12.65% mg/g GAE) methods. Antiproliferative study indicated that V. Amygdalina crude extract have great potential as antiproliferative compounds against various cancer cell lines and can significantly inhibit the growth of MCF-7 and HT-29 cancer cells. The methanol V. Amygdalina extract has a broad spectrum of activity by inhibiting the growth of MCF-7 and HT-29 cancer cells. |
| title | Study On Antioxidant Capacity And Anticancer Activity Of Bismillah Leaf ( Vernoniaamygdalina ) |
| title_full | Study On Antioxidant Capacity And Anticancer Activity Of Bismillah Leaf ( Vernoniaamygdalina ) |
| title_fullStr | Study On Antioxidant Capacity And Anticancer Activity Of Bismillah Leaf ( Vernoniaamygdalina ) |
| title_full_unstemmed | Study On Antioxidant Capacity And Anticancer Activity Of Bismillah Leaf ( Vernoniaamygdalina ) |
| title_short | Study On Antioxidant Capacity And Anticancer Activity Of Bismillah Leaf ( Vernoniaamygdalina ) |
| title_sort | study on antioxidant capacity and anticancer activity of bismillah leaf ( vernoniaamygdalina ) |