Search Results - Sykes, David A.

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  1. 1
    A role for rebinding in the prevalence of on-target side effects of clinically used antipsychotics

    A role for rebinding in the prevalence of on-target side effects of clinically used antipsychotics by Sykes, David A

    Published 2020
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  2. 2
    Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors

    Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors by Sykes, David A., Moore, Holly, Stott, Lisa, Holliday, Nicholas, Javitch, Jonathan A., Lane, J. Robert, Charlton, Steven J.

    Published 2017
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  3. 3
    Long receptor residence time of C26 contributes to super agonist activity at the human β2 adrenoceptor

    Long receptor residence time of C26 contributes to super agonist activity at the human β2 adrenoceptor by Rosethorne, Elizabeth M., Bradley, Michelle E., Gherbi, Karolina, Sykes, David A., Sattikar, Afrah, Wright, John D., Renard, Emilie, Trifilieff, A., Fairhurst, Robin A., Charlton, Steven J.

    Published 2016
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  4. 4
    The role of kinetic context in apparent biased agonism at GPCRs

    The role of kinetic context in apparent biased agonism at GPCRs by Klein Herenbrink, Carmen, Sykes, David A., Donthamsetti, Prashant, Canals, Meritxell, Coudrat, Thomas, Shonberg, Jeremy, Scammells, Peter J., Capuano, Ben, Sexton, Patrick M., Charlton, Steven J., Javitch, Jonathan, Christopoulos, Arthur, Lane, J. Robert

    Published 2016
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  5. 5
    Uncoupling the structure–activity relationships of β2 adrenergic receptor ligands from membrane binding

    Uncoupling the structure–activity relationships of β2 adrenergic receptor ligands from membrane binding by Dickson, Callum J., Hornak, Victor, Velez-Vega, Camilo, McKay, Daniel J.J., Reilly, John, Sandham, David A., Shaw, Duncan, Fairhurst, Robin A., Charlton, Steven J., Sykes, David A., Pearlstein, Robert, Duca, Jose S.

    Published 2016
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  6. 6
    Discovery of fevipiprant (NVP-QAW039), a potent and selective DP2 receptor antagonist for treatment of asthma

    Discovery of fevipiprant (NVP-QAW039), a potent and selective DP2 receptor antagonist for treatment of asthma by Sandham, David A., Barker, Lucy, Brown, Lyndon, Brown, Zarin, Budd, David, Charlton, Steven J., Chatterjee, Devnanden, Cox, Brian, Dubois, Gerald, Duggan, Nicholas, Hall, Edward, Hatto, Julia, Maas, Janet, Manini, Jodie, Profit, Rachael, Riddy, Darren, Ritchie, Catherine, Sohal, Bindi, Shaw, Duncan, Stringer, Rowan, Sykes, David A., Thomas, Matthew, Turner, Katherine L., Watson, Simon J., West, Ryan, Willard, Elisabeth, Williams, Gareth, Willis, Jennifer

    Published 2017
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