Search Results - Stoddart, Leigh A.

  • Showing 1 - 11 results of 11
Refine Results
  1. 1
    Fragment-based discovery of subtype-selective adenosine receptor ligands from homology models

    Fragment-based discovery of subtype-selective adenosine receptor ligands from homology models by Ranganathan, Anirudh, Stoddart, Leigh A., Hill, Stephen J., Carlsson, Jens

    Published 2015
    Get full text
  2. 2
    Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein-dependent signalling and Gi-independent receptor internalization

    Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein-dependent signalling and Gi-independent receptor internalization by Stoddart, Leigh A., Kellam, Barrie, Briddon, Stephen J., Hill, Stephen J.

    Published 2014
    Get full text
  3. 3
    Use of a new proximity assay (NanoBRET) to investigate the ligand binding characteristics of three fluorescent ligands to the human β1-adrenoceptor expressed in HEK-293 cells

    Use of a new proximity assay (NanoBRET) to investigate the ligand binding characteristics of three fluorescent ligands to the human β1-adrenoceptor expressed in HEK-293 cells by Soave, Mark, Stoddart, Leigh A., Brown, Alastair, Woolard, Jeanette, Hill, Stephen J.

    Published 2016
    Get full text
  4. 4
    Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist

    Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist by Stoddart, Leigh A., Vernall, Andrea J., Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.

    Published 2015
    Get full text
  5. 5
    A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells

    A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells by Arruda, Maria Augusta, Stoddart, Leigh A., Gherbi, Karolina, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.

    Published 2017
    Get full text
  6. 6
    Synthesis, biological evaluation, and utility of fluorescent ligands targeting the μ-opioid receptor

    Synthesis, biological evaluation, and utility of fluorescent ligands targeting the μ-opioid receptor by Schembri, Luke S., Stoddart, Leigh A., Briddon, Stephen J., Kellam, Barrie, Canals, Meritxell, Graham, Bim, Scammells, Peter J.

    Published 2015
    Get full text
  7. 7
    Synthesis and evaluation of the first fluorescent antagonists of the human P2Y2 receptor based on AR-C118925

    Synthesis and evaluation of the first fluorescent antagonists of the human P2Y2 receptor based on AR-C118925 by Conroy, Sean, Kindon, Nicholas, Glenn, Jacqueline, Stoddart, Leigh A., Lewis, Richard James, Hill, Stephen J., Kellam, Barrie, Stocks, Michael J.

    Published 2018
    Get full text
  8. 8
    Conversion of a non-selective adenosine receptor antagonist into A3-selective high affinity fluorescent probes using peptide-based linkers

    Conversion of a non-selective adenosine receptor antagonist into A3-selective high affinity fluorescent probes using peptide-based linkers by Vernall, Andrea J., Stoddart, Leigh A., Briddon, Stephen J., Ng, Hui Wen, Laughton, Charles A., Doughty, Stephen W., Hill, Stephen J., Kellam, Barrie

    Published 2013
    Get full text
  9. 9
    Application of BRET to monitor ligand binding to GPCRs

    Application of BRET to monitor ligand binding to GPCRs by Stoddart, Leigh A., Johnstone, Elizabeth K.M., Wheal, Amanda J., Goulding, Joelle, Robers, Matthew B., Machleidt, Thomas, Wood, Keith V., Hill, Stephen J., Pfleger, Kevin D.G.

    Published 2015
    Get full text
  10. 10
    Design and elaboration of a tractable tricyclic scaffold to synthesize druglike inhibitors of dipeptidyl peptidase-4 (DPP-4), antagonists of the C–C Chemokine Receptor Type 5 (CCR5), and highly potent and selective phosphoinositol-3 Kinase δ (PI3Kδ) inhibitors

    Design and elaboration of a tractable tricyclic scaffold to synthesize druglike inhibitors of dipeptidyl peptidase-4 (DPP-4), antagonists of the C–C Chemokine Receptor Type 5 (CCR5... by Schwehm, Carolin, Kellam, Barrie, Garces, Aimie, Hill, Stephen J., Kindon, Nicholas, Bradshaw, Tracey D., Li, Jin, Macdonald, Simon J.F., Rowedder, James E., Stoddart, Leigh A., Stocks, Michael

    Published 2017
    Get full text
  11. 11
    Development of novel fluorescent histamine H₁-receptor antagonists to study ligand-binding kinetics in living cells

    Development of novel fluorescent histamine H₁-receptor antagonists to study ligand-binding kinetics in living cells by Stoddart, Leigh A., Vernall, Andrea J., Bouzo-Lorenzo, Monica, Bosma, Reggie, Kooistra, Albert J., de Graaf, Chris, Vischer, Henry F., Leurs, Rob, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.

    Published 2018
    Get full text

Search Tools: