Search Results - Mistry, Shailesh N.

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  1. 1
    Structure activity relationships of novel and selective beta1-adrenoreceptor ligands

    Structure activity relationships of novel and selective beta1-adrenoreceptor ligands by Mistry, Shailesh N.

    Published 2009
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  2. 2
    The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor

    The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor by Mistry, Shailesh N., Baker, Jillian G.

    Published 2016
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  3. 3
    The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor

    The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor by Mistry, Shailesh N., Baker, Jillian G.

    Published 2016
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  4. 4
    GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors

    GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors by Emtage, Abigail L., Mistry, Shailesh N., Fischer, Peter M., Kellam, Barrie, Laughton, Charles A.

    Published 2016
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  5. 5
    Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor

    Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor by Mistry, Shailesh N., Valant, Celine, Sexton, Patrick M., Capuano, Ben, Christopoulos, Arthur, Scammells, Peter J.

    Published 2013
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  6. 6
    Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists

    Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists by Mistry, Shailesh N., Baker, Jillian G., Fischer, Peter M., Hill, Stephen J., Gardiner, Sheila M., Kellam, Barrie

    Published 2013
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  7. 7
    Novel fused arylpyrimidinone based allosteric modulators of the M1 muscarinic acetylcholine receptor

    Novel fused arylpyrimidinone based allosteric modulators of the M1 muscarinic acetylcholine receptor by Mistry, Shailesh N., Lim, Herman, Jörg, Manuela, Capuano, Ben, Christopoulos, Arthur, Lane, J. Robert, Scammells, Peter J.

    Published 2016
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  8. 8
    In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist.

    In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist. by Baker, Jillian G., Mistry, Shailesh N., Fischer, Peter M., Hill, Stephen J., Gardiner, Sheila M., Kellam, Barrie

    Published 2012
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  9. 9
    Screening the medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum aminopeptidases, M1, M17 and M18

    Screening the medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum aminopeptidases, M1, M17 and M18 by Paiardini, Alessandro, Bamert, Rebecca S., Kannan-Sivaraman, Komagal, Drinkwater, Nyssa, Mistry, Shailesh N., Scammells, Peter J., McGowan, Sheena

    Published 2015
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  10. 10
    Structure–activity study of N-((trans)-4-(2-(7-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a bitopic ligand that acts as a negative allosteric modulator of the dopamine D2 receptor

    Structure–activity study of N-((trans)-4-(2-(7-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a bitopic ligand that acts as a negative... by Shonberg, Jeremy, Draper-Joyce, Christopher, Mistry, Shailesh N., Christopoulos, Arthur, Scammells, Peter J., Lane, J. Robert, Capuano, Ben

    Published 2015
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  11. 11
    Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors

    Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors by Baker, Jillian G., Adams, Luke A., Salchow, Karolina, Mistry, Shailesh N., Middleton, Richard J., Hill, Stephen J., Kellam, Barrie

    Published 2011
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  12. 12
    Synthesis and characterization of high-affinity 4, 4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors

    Synthesis and characterization of high-affinity 4, 4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors by Baker, Jillian G., Adams, Luke A., Salchow, Karolina, Mistry, Shailesh N., Middleton, Richard J., Hill, Stephen J., Kellam, Barrie

    Published 2011
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  13. 13
    Mechanistic insights into allosteric structure-function relationships at the M1 muscarinic acetylcholine receptor

    Mechanistic insights into allosteric structure-function relationships at the M1 muscarinic acetylcholine receptor by Abdul-Ridha, Alaa, Lane, J. Robert, Mistry, Shailesh N., Lopez, Laura, Sexton, Patrick M., Scammells, Peter J., Christopoulos, Arthur, Canals, Meritxell

    Published 2014
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  14. 14
    Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor

    Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor by Abdul-Ridha, Alaa, López, Laura, Keov, Peter, Thal, David M., Mistry, Shailesh N., Sexton, Patrick M., Lane, J. Robert, Canals, Meritxell, Christopoulos, Arthur

    Published 2014
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  15. 15
    4-Phenylpyridin-2-one derivatives: a novel class of positive allosteric modulator of the M1 muscarinic acetylcholine receptor

    4-Phenylpyridin-2-one derivatives: a novel class of positive allosteric modulator of the M1 muscarinic acetylcholine receptor by Mistry, Shailesh N., Jörg, Manuela, Lim, Herman, Vinh, Natalie B., Sexton, Patrick M., Capuano, Ben, Christopoulos, Arthur, Lane, J. Robert, Scammells, Peter J.

    Published 2015
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  16. 16
    A thieno[2,3-d]pyrimidine scaffold is a novel negative allosteric modulator of the dopamine D2 receptor

    A thieno[2,3-d]pyrimidine scaffold is a novel negative allosteric modulator of the dopamine D2 receptor by Fyfe, Tim J., Zarzycka, Barbara, Lim, Herman D., Kellam, Barrie, Mistry, Shailesh N., Katrich, Vsevolod, Scammells, Peter J., Lane, J. Robert, Capuano, Ben

    Published 2018
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  17. 17
    Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics

    Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics by Cook, A.E., Mistry, Shailesh N., Gregory, K.J., Furness, S.G.B., Sexton, Patrick M., Scammells, Peter J., Conigrave, A.D., Christopoulos, Arthur, Leach, K.

    Published 2014
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  18. 18
    Discovery of a novel class of negative allosteric modulator of the dopamine D2 receptor through fragmentation of a bitopic ligand

    Discovery of a novel class of negative allosteric modulator of the dopamine D2 receptor through fragmentation of a bitopic ligand by Mistry, Shailesh N., Shonberg, Jeremy, Draper-Joyce, Christopher J., Klein Herenbrink, Carmen, Michino, Mayako, Shi, Lei, Christopoulos, Arthur, Capuano, Ben, Scammells, Peter J., Lane, J. Robert

    Published 2015
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  19. 19
    Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors

    Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors by Mistry, Shailesh N., Drinkwater, Nyssa, Ruggeri, Chiara, Sivaraman, Komagal Kannan, Loganathan, Sasdekumar, Fletcher, Sabine, Drag, Marcin, Paiardini, Alessandro, Avery, Vicky M., Scammells, Peter J., McGowan, Sheena

    Published 2014
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  20. 20
    Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors

    Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors by Mistry, Shailesh N., Drinkwater, Nyssa, Ruggeri, Chiara, Sivaraman, Komagal Kannan, Loganathan, Sasdekumar, Fletcher, Sabine, Drag, Marcin, Paiardini, Alessandro, Avery, Vicky M., Scammells, Peter J., McGowan, Sheena

    Published 2014
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