Search Results - Baker, T. G.

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  1. 1
    The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor

    The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor by Mistry, Shailesh N., Baker, Jillian G.

    Published 2016
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  2. 2
    The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor

    The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor by Mistry, Shailesh N., Baker, Jillian G.

    Published 2016
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  3. 3
    Thermal Performance Curves Reveal Alternative Energy Pathways at Stressful Temperatures: A Multi-Trait Analysis of Phenotypic Plasticity in Thalassiosira Pseudonana

    Thermal Performance Curves Reveal Alternative Energy Pathways at Stressful Temperatures: A Multi-Trait Analysis of Phenotypic Plasticity in Thalassiosira Pseudonana by Baker, K.G., Doblin, M.A., Robinson, Charlotte

    Published 2015
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  4. 4
    Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling

    Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling by Baker, Jillian G., Hill, Stephen J., Summers, Roger J.

    Published 2011
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  5. 5
    Similarity- and substructure-based development of β2-adrenergic receptor ligands based on unusual scaffolds

    Similarity- and substructure-based development of β2-adrenergic receptor ligands based on unusual scaffolds by Schmidt, Denis, Gunera, Jakub, Baker, Jillian G., Kolb, Peter

    Published 2017
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  6. 6
    Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor

    Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor by Baker, Jillian G., Hill, Stephen J., Proudman, Richard G.W.

    Published 2013
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  7. 7
    Salmeterol's extreme b2 selectivity is due to residues in both extracellular loops and transmembrane domains

    Salmeterol's extreme b2 selectivity is due to residues in both extracellular loops and transmembrane domains by Baker, Jillian G., Proudman, Richard G.W., Hill, Stephen J.

    Published 2015
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  8. 8
    Identification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human 1-adrenoceptor

    Identification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human 1-adrenoceptor by Baker, Jillian G., Proudman, Richard G.W., Hill, Stephen J.

    Published 2014
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  9. 9
    Potentiation of testicular cytotoxicity by the alkyltransferase inhibitor O6 benzylguanine and the 5-fluorouracil/N-(2-chloroethyl)-N-nitrosourea molecular combination, B.4152

    Potentiation of testicular cytotoxicity by the alkyltransferase inhibitor O6 benzylguanine and the 5-fluorouracil/N-(2-chloroethyl)-N-nitrosourea molecular combination, B.4152 by Thompson, Michael J., Abdul Rahman, Suzanah, Baker, Theresa G., Bibby, Michael Charles

    Published 1996
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  10. 10
    Negative cooperativity across 1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 1-adrenoceptor binding conformation

    Negative cooperativity across 1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 1-adrenoceptor binding conformation by Gherbi, Karolina, May, Lauren T., Baker, Jillian G., Briddon, Stephen J., Hill, Stephen J.

    Published 2015
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  11. 11
    Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantative comparison of cellular and cardiovascular pharmacological responses

    Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantative comparison of cellular and cardiovascular pharmacological responses by Baker, Jillian G., Kemp, Philip, March, Julie, Fretwell, Laurice, Hill, Stephen J., Gardiner, Sheila M.

    Published 2011
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  12. 12
    Simulation fails to replicate stress in trainees performing a technical procedure in the clinical environment

    Simulation fails to replicate stress in trainees performing a technical procedure in the clinical environment by Baker, B.G., Bhalla, Ashish, Doleman, Brett, Yarnold, E., Simons, S., Lund, Jonathan N., Williams, John P.

    Published 2016
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  13. 13
    Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists

    Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists by Mistry, Shailesh N., Baker, Jillian G., Fischer, Peter M., Hill, Stephen J., Gardiner, Sheila M., Kellam, Barrie

    Published 2013
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  14. 14
    Pharmacological analysis and structure determination of 7-methylcyanopindolol–bound b1-adrenergic receptor

    Pharmacological analysis and structure determination of 7-methylcyanopindolol–bound b1-adrenergic receptor by Sato, Tomomi, Baker, Jillian G., Warne, Tony, Brown, Giles A., Leslie, Andrew, Congreve, Miles, Tate, Christopher G.

    Published 2015
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  15. 15
    In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist.

    In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist. by Baker, Jillian G., Mistry, Shailesh N., Fischer, Peter M., Hill, Stephen J., Gardiner, Sheila M., Kellam, Barrie

    Published 2012
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  16. 16
    Role of O6-alkylguanine-DNA alkyltransferase in the resistance of mouse spermatogenic cells to O6-alkylating agents

    Role of O6-alkylguanine-DNA alkyltransferase in the resistance of mouse spermatogenic cells to O6-alkylating agents by Thompson, M. J., Abdul Rahman, Suzanah, Baker, T. G., Rafferty, J. A, Margison, G. P., Bibby, M. C

    Published 2000
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  17. 17
    Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors

    Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors by Baker, Jillian G., Adams, Luke A., Salchow, Karolina, Mistry, Shailesh N., Middleton, Richard J., Hill, Stephen J., Kellam, Barrie

    Published 2011
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  18. 18
    Synthesis and characterization of high-affinity 4, 4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors

    Synthesis and characterization of high-affinity 4, 4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors by Baker, Jillian G., Adams, Luke A., Salchow, Karolina, Mistry, Shailesh N., Middleton, Richard J., Hill, Stephen J., Kellam, Barrie

    Published 2011
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  19. 19
    Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease

    Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease by Baker, Jillian G., Gardiner, Sheila M., Woolard, Jeanette, Fromont, Christophe, Jadhav, Gopal P., Mistry, Shailesh N., Thompson, Kevin S.J., Kellam, Barrie, Hill, Stephen J., Fischer, Peter M.

    Published 2017
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