Search Results - Baker, Jillian G.

  • Showing 1 - 15 results of 15
Refine Results
  1. 1
    The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor

    The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor by Mistry, Shailesh N., Baker, Jillian G.

    Published 2016
    Get full text
  2. 2
    The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor

    The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor by Mistry, Shailesh N., Baker, Jillian G.

    Published 2016
    Get full text
  3. 3
    Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling

    Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling by Baker, Jillian G., Hill, Stephen J., Summers, Roger J.

    Published 2011
    Get full text
  4. 4
    Similarity- and substructure-based development of β2-adrenergic receptor ligands based on unusual scaffolds

    Similarity- and substructure-based development of β2-adrenergic receptor ligands based on unusual scaffolds by Schmidt, Denis, Gunera, Jakub, Baker, Jillian G., Kolb, Peter

    Published 2017
    Get full text
  5. 5
    Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor

    Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor by Baker, Jillian G., Hill, Stephen J., Proudman, Richard G.W.

    Published 2013
    Get full text
  6. 6
    Salmeterol's extreme b2 selectivity is due to residues in both extracellular loops and transmembrane domains

    Salmeterol's extreme b2 selectivity is due to residues in both extracellular loops and transmembrane domains by Baker, Jillian G., Proudman, Richard G.W., Hill, Stephen J.

    Published 2015
    Get full text
  7. 7
    Identification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human 1-adrenoceptor

    Identification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human 1-adrenoceptor by Baker, Jillian G., Proudman, Richard G.W., Hill, Stephen J.

    Published 2014
    Get full text
  8. 8
    Negative cooperativity across 1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 1-adrenoceptor binding conformation

    Negative cooperativity across 1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 1-adrenoceptor binding conformation by Gherbi, Karolina, May, Lauren T., Baker, Jillian G., Briddon, Stephen J., Hill, Stephen J.

    Published 2015
    Get full text
  9. 9
    Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantative comparison of cellular and cardiovascular pharmacological responses

    Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantative comparison of cellular and cardiovascular pharmacological responses by Baker, Jillian G., Kemp, Philip, March, Julie, Fretwell, Laurice, Hill, Stephen J., Gardiner, Sheila M.

    Published 2011
    Get full text
  10. 10
    Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists

    Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists by Mistry, Shailesh N., Baker, Jillian G., Fischer, Peter M., Hill, Stephen J., Gardiner, Sheila M., Kellam, Barrie

    Published 2013
    Get full text
  11. 11
    Pharmacological analysis and structure determination of 7-methylcyanopindolol–bound b1-adrenergic receptor

    Pharmacological analysis and structure determination of 7-methylcyanopindolol–bound b1-adrenergic receptor by Sato, Tomomi, Baker, Jillian G., Warne, Tony, Brown, Giles A., Leslie, Andrew, Congreve, Miles, Tate, Christopher G.

    Published 2015
    Get full text
  12. 12
    In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist.

    In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist. by Baker, Jillian G., Mistry, Shailesh N., Fischer, Peter M., Hill, Stephen J., Gardiner, Sheila M., Kellam, Barrie

    Published 2012
    Get full text
  13. 13
    Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors

    Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors by Baker, Jillian G., Adams, Luke A., Salchow, Karolina, Mistry, Shailesh N., Middleton, Richard J., Hill, Stephen J., Kellam, Barrie

    Published 2011
    Get full text
  14. 14
    Synthesis and characterization of high-affinity 4, 4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors

    Synthesis and characterization of high-affinity 4, 4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors by Baker, Jillian G., Adams, Luke A., Salchow, Karolina, Mistry, Shailesh N., Middleton, Richard J., Hill, Stephen J., Kellam, Barrie

    Published 2011
    Get full text
  15. 15
    Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease

    Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease by Baker, Jillian G., Gardiner, Sheila M., Woolard, Jeanette, Fromont, Christophe, Jadhav, Gopal P., Mistry, Shailesh N., Thompson, Kevin S.J., Kellam, Barrie, Hill, Stephen J., Fischer, Peter M.

    Published 2017
    Get full text

Search Tools: