Anti-C1q Autoantibodies, Novel Tests, and Clinical Consequences

by Mahler, Michael, van Schaarenburg, Rosanne A., Trouw, Leendert A.
Published 2013

C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation

by Trouw, Leendert A., Nilsson, Sara C., Gonçalves, Isabel, Landberg, Göran, Blom, Anna M.
Published 2005

Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP antibodie...

by Debbie M. Boeters, Leendert A. Trouw, Annette H. M. van der Helm-van Mil, Hanna W. van Steenbergen
Published 2018-05-01

The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA

by Suwannalai, Parawee, Willemze, Annemiek, van Toorn, Linda, Stoeken-Rijsbergen, Gerrie, Levarht, Nivine, Drijfhout, Jan Wouter, J Huizinga, Tom W, M Toes, Rene E, Trouw, Leendert A
Published 2011

Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome

by Foltyn Zadura, Anna, Zipfel, Peter F, Bokarewa, Maria I, Sturfelt, Gunnar, Jönsen, Andreas, Nilsson, Sara C, Hillarp, Andreas, Saxne, Tore, Trouw, Leendert A, Blom, Anna M
Published 2012

C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus

by van Schaarenburg, Rosanne A., Magro-Checa, César, Bakker, Jaap A., Teng, Y. K. Onno, Bajema, Ingeborg M., Huizinga, Tom W., Steup-Beekman, Gerda M., Trouw, Leendert A.
Published 2016

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk...

by Humphreys, Jennifer H, Verheul, Marije K, Barton, Anne, MacGregor, Alexander J, Lunt, Mark, Toes, Rene EM, Symmons, Deborah PM, Trouw, Leendert A, Verstappen, Suzanne MM
Published 2016

Antibodies against carbamylated proteins and cyclic citrullinated peptides in systemic lupus erythematosus: results from two well-defined European cohorts

by Ziegelasch, Michael, van Delft, Myrthe A. M., Wallin, Philip, Skogh, Thomas, Magro-Checa, César, Steup-Beekman, Gerda M., Trouw, Leendert A., Kastbom, Alf, Sjöwall, Christopher
Published 2016

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

by Brink, Mikael, Hansson, Monika, Mathsson-Alm, Linda, Wijayatunga, Priyantha, Verheul, Marije K., Trouw, Leendert A., Holmdahl, Rikard, Rönnelid, Johan, Klareskog, Lars, Rantapää-Dahlqvist, Solbritt
Published 2016

Antibodies Specific for Carbamylated Proteins Precede the Onset of Clinical Symptoms in Mice with Collagen Induced Arthritis

by Stoop, Jeroen N., Liu, Bi-Sheng, Shi, Jing, Jansen, Diahann T. S. L., Hegen, Martin, Huizinga, Tom W. J., Trouw, Leendert A., Toes, René E. M.
Published 2014

Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with...

by Brink, Mikael, Verheul, Marije K, Rönnelid, Johan, Berglin, Ewa, Holmdahl, Rikard, Toes, Rene EM, Klareskog, Lars, Trouw, Leendert A, Rantapää-Dahlqvist, Solbritt
Published 2015

The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical

by Debbie M. Boeters, Lukas Mangnus, Sofia Ajeganova, Elisabet Lindqvist, Björn Svensson, René E. M. Toes, Leendert A. Trouw, Tom W. J. Huizinga, Francis Berenbaum, Jacques Morel, Solbritt Rantapää-Dahlqvist, Annette H. M. van der Helm-van Mil
Published 2017-05-01

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

by Myrthe A. M. van Delft, Marije K. Verheul, Leonie E. Burgers, Veerle F. A. M. Derksen, Annette H. M. van der Helm-van Mil, Diane van der Woude, Tom W. J. Huizinga, René E. M. Toes, Leendert A. Trouw
Published 2017-08-01

Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis

by Habets, Kim L.L., Trouw, Leendert A., Levarht, E.W. Nivine, Korporaal, Suzanne J.A., Habets, Petra A.M., de Groot, Philip, Huizinga, Tom W.J., Toes, René E.M.
Published 2015

MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF

by Boeters, Debbie M., Nieuwenhuis, Wouter P., Verheul, Marije K., Newsum, Elize C., Reijnierse, Monique, Toes, René E. M., Trouw, Leendert A., van der Helm-van Mil, Annette H. M.
Published 2016

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting

by van Heemst, Jurgen, Trouw, Leendert A., Nogueira, Leonor, van Steenbergen, Hanna W., van der Helm-van Mil, Annette H. M., Allaart, Cornelia F., Serre, Guy, Holmdahl, Rikard, Huizinga, Tom W. J., Toes, René E. M., van der Woude, Diane
Published 2015

Rheumatoid arthritis–associated autoantibodies in non–rheumatoid arthritis patients with mucosal inflammation: a case–control study

by Janssen, Koen M J, de Smit, Menke J, Brouwer, Elisabeth, de Kok, Fenne A C, Kraan, Jan, Altenburg, Josje, Verheul, Marije K, Trouw, Leendert A, van Winkelhoff, Arie Jan, Vissink, Arjan, Westra, Johanna
Published 2015

The valence-fluctuating ground state of plutonium

by Janoschek, Marc, Das, Pinaki, Chakrabarti, Bismayan, Abernathy, Douglas L., Lumsden, Mark D., Lawrence, John M., Thompson, Joe D., Lander, Gerard H., Mitchell, Jeremy N., Richmond, Scott, Ramos, Mike, Trouw, Frans, Zhu, Jian-Xin, Haule, Kristjan, Kotliar, Gabriel, Bauer, Eric D.
Published 2015

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis

by Shi, Jing, van Steenbergen, Hanna W., van Nies, Jessica A. B., Levarht, E. W. Nivine, Huizinga, Tom W. J., van der Helm-van Mil, Annette H. M., Toes, René E. M., Trouw, Leendert A.
Published 2015

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter c...

by van Wesemael, Tineke J., Ajeganova, Sofia, Humphreys, Jennifer, Terao, Chikashi, Muhammad, Ammar, Symmons, Deborah P. M., MacGregor, Alex J., Hafström, Ingiäld, Trouw, Leendert A., van der Helm-van Mil, Annette H. M., Huizinga, Tom W. J., Mimori, Tsuneyo, Toes, René E. M., Matsuda, Fumihiko, Svensson, Björn, Verstappen, Suzanne M. M., van der Woude, Diane
Published 2016