Targeted mutagenesis in a human-parasitic nematode.

by Spencer S Gang, Michelle L Castelletto, Astra S Bryant, Emily Yang, Nicholas Mancuso, Jacqueline B Lopez, Matteo Pellegrini, Elissa A Hallem
Published 2017-10-01

Experience-dependent olfactory behaviors of the parasitic nematode Heligmosomoides polygyrus.

by Felicitas Ruiz, Michelle L Castelletto, Spencer S Gang, Elissa A Hallem
Published 2017-11-01

A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors.

by Valerio Leoni, Andrea Vannini, Valentina Gatta, Julie Rambaldi, Mara Sanapo, Catia Barboni, Anna Zaghini, Patrizia Nanni, Pier-Luigi Lollini, Costanza Casiraghi, Gabriella Campadelli-Fiume
Published 2018-08-01

The Epstein Barr virus circRNAome.

by Nathan Ungerleider, Monica Concha, Zhen Lin, Claire Roberts, Xia Wang, Subing Cao, Melody Baddoo, Walter N Moss, Yi Yu, Michael Seddon, Terri Lehman, Scott Tibbetts, Rolf Renne, Yan Dong, Erik K Flemington
Published 2018-08-01

Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2.

by Wenfei Song, Miao Gui, Xinquan Wang, Ye Xiang
Published 2018-08-01

Inhibition of murine herpesvirus-68 replication by IFN-gamma in macrophages is counteracted by the induction of SOCS1 expression.

by Yong Shen, Saisai Wang, Fangfang Sun, Gang Zheng, Tingting Wu, Yushen Du, Suzhan Zhang, Jing Qian, Ren Sun
Published 2018-08-01

RNA decay is an antiviral defense in plants that is counteracted by viral RNA silencing suppressors.

by Fangfang Li, Aiming Wang
Published 2018-08-01

The crystal structure of KSHV ORF57 reveals dimeric active sites important for protein stability and function.

by Fei Yuan, Zeng-Qiang Gao, Vladimir Majerciak, Lei Bai, Meng-Lu Hu, Xiao-Xi Lin, Zhi-Ming Zheng, Yu-Hui Dong, Ke Lan
Published 2018-08-01

Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces.

by Hongbo Guo, Huib Rabouw, Anne Slomp, Meiling Dai, Floor van der Vegt, Jan W M van Lent, Ryan McBride, James C Paulson, Raoul J de Groot, Frank J M van Kuppeveld, Erik de Vries, Cornelis A M de Haan
Published 2018-08-01

Clostridium difficile exosporium cysteine-rich proteins are essential for the morphogenesis of the exosporium layer, spore resistance, and affect C. difficile pathogenesis.

by Paulina Calderón-Romero, Pablo Castro-Córdova, Rodrigo Reyes-Ramírez, Mauro Milano-Céspedes, Enzo Guerrero-Araya, Marjorie Pizarro-Guajardo, Valeria Olguín-Araneda, Fernando Gil, Daniel Paredes-Sabja
Published 2018-08-01

A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism.

by Eirini D Tseligka, Komla Sobo, Luc Stoppini, Valeria Cagno, Fabien Abdul, Isabelle Piuz, Pascal Meylan, Song Huang, Samuel Constant, Caroline Tapparel
Published 2018-08-01

S-acylation mediates Mungbean yellow mosaic virus AC4 localization to the plasma membrane and in turns gene silencing suppression.

by Anna Vittoria Carluccio, Maria Isabella Prigigallo, Tabata Rosas-Diaz, Rosa Lozano-Duran, Livia Stavolone
Published 2018-08-01

Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice.

by Wolfgang Koestner, Julia Spanier, Tanja Klause, Pia-K Tegtmeyer, Jennifer Becker, Vanessa Herder, Katharina Borst, Daniel Todt, Stefan Lienenklaus, Ingo Gerhauser, Claudia N Detje, Robert Geffers, Martijn A Langereis, Florian W R Vondran, Qinggong Yuan, Frank J M van Kuppeveld, Michael Ott, Peter Staeheli, Eike Steinmann, Wolfgang Baumgärtner, Frank Wacker, Ulrich Kalinke
Published 2018-08-01

Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2.

by Andrea Kinga Marias Furuya, Hamayun J Sharifi, Robert M Jellinger, Paul Cristofano, Binshan Shi, Carlos M C de Noronha
Published 2016-04-01

Type I IFNs drive hematopoietic stem and progenitor cell collapse via impaired proliferation and increased RIPK1-dependent cell death during shock-like ehrlichial infection.

by Julianne N P Smith, Yubin Zhang, Jing Jing Li, Amanda McCabe, Hui Jin Jo, Jackson Maloney, Katherine C MacNamara
Published 2018-08-01

Five pillars of centromeric chromatin in fungal pathogens.

by Vikas Yadav, Lakshmi Sreekumar, Krishnendu Guin, Kaustuv Sanyal
Published 2018-08-01

Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap.

by Philipp A Ilinykh, Rodrigo I Santos, Bronwyn M Gunn, Natalia A Kuzmina, Xiaoli Shen, Kai Huang, Pavlo Gilchuk, Andrew I Flyak, Patrick Younan, Galit Alter, James E Crowe, Alexander Bukreyev
Published 2018-08-01

Immobility in the sedentary plant-parasitic nematode H. glycines is associated with remodeling of neuromuscular tissue.

by Ziduan Han, Sita Thapa, Ursula Reuter-Carlson, Hannah Reed, Michael Gates, Kris N Lambert, Nathan E Schroeder
Published 2018-08-01

Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice.

by Stephanie L Brandt, Nathan Klopfenstein, Soujuan Wang, Seth Winfree, Brian P McCarthy, Paul R Territo, Lloyd Miller, C Henrique Serezani
Published 2018-08-01

Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins.

by Thorsten Brink, Veronika Leiss, Peter Siegert, Doris Jehle, Julia K Ebner, Carsten Schwan, Aliaksei Shymanets, Sebastian Wiese, Bernd Nürnberg, Michael Hensel, Klaus Aktories, Joachim H C Orth
Published 2018-08-01