Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very large chromatin-regulating proteins

Compiling a comprehensive list of cancer driver genes is imperative for oncology diagnostics and drug development. While driver genes are typically discovered by analysis of tumor genomes, infrequently mutated driver genes often evade detection due to limited sample sizes. Here, we address sample si...

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Bibliographic Details
Main Authors: Waks, Zeev, Weissbrod, Omer, Carmeli, Boaz, Norel, Raquel, Utro, Filippo, Goldschmidt, Yaara
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180091/