Validation of tumor protein marker quantification by two independent automated immunofluorescence image analysis platforms

Protein marker levels in formalin-fixed, paraffin-embedded tissue sections traditionally have been assayed by chromogenic immunohistochemistry and evaluated visually by pathologists. Pathologist scoring of chromogen staining intensity is subjective and generates low-resolution ordinal or nominal dat...

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Bibliographic Details
Main Authors: Peck, Amy R, Girondo, Melanie A, Liu, Chengbao, Kovatich, Albert J, Hooke, Jeffrey A, Shriver, Craig D, Hu, Hai, Mitchell, Edith P, Freydin, Boris, Hyslop, Terry, Chervoneva, Inna, Rui, Hallgeir
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047958/