Redox-Dependent Modulation of T-Type Ca2+ Channels in Sensory Neurons Contributes to Acute Anti-Nociceptive Effect of Substance P

Aims: Neuropeptide substance P (SP) is produced and released by a subset of peripheral sensory neurons that respond to tissue damage (nociceptors). SP exerts excitatory effects in the central nervous system, but peripheral SP actions are still poorly understood; therefore, here, we aimed at investig...

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Bibliographic Details
Main Authors: Huang, Dongyang, Huang, Sha, Gao, Haixia, Liu, Yani, Qi, Jinlong, Chen, Pingping, Wang, Caixue, Scragg, Jason L., Vakurov, Alexander, Peers, Chris, Du, Xiaona, Zhang, Hailin, Gamper, Nikita
Format: Online
Language:English
Published: Mary Ann Liebert, Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971421/