Long-term dynamics of multisite phosphorylation
A systematic framework for exploring the long-term dynamics of a reaction network is applied to a minimal model of ERK regulation that distinguishes both monophosphorylated forms and allows for nonzero enzyme processivity. Bistability and oscillations can be observed at high levels of processivity.
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2016
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945148/ |