Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features
Background: During the last two decades, protein aggregation at all organismal levels, from viruses to humans, has emerged from a neglected area of protein science to become a central issue in biology and biomedicine. This article constitutes a risk-based review aimed at supporting an etiologic scen...
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pubmed-49040102016-07-04 Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features de Pedro-Cuesta, Jesús Martínez-Martín, Pablo Rábano, Alberto Ruiz-Tovar, María Alcalde-Cabero, Enrique Calero, Miguel Neuroscience Background: During the last two decades, protein aggregation at all organismal levels, from viruses to humans, has emerged from a neglected area of protein science to become a central issue in biology and biomedicine. This article constitutes a risk-based review aimed at supporting an etiologic scenario of selected, sporadic, protein-associated, i.e., conformational, neurodegenerative disorders (NDDs), and their vascular- and metabolic-associated ailments. Frontiers Media S.A. 2016-06-13 /pmc/articles/PMC4904010/ /pubmed/27378910 http://dx.doi.org/10.3389/fnagi.2016.00138 Text en Copyright © 2016 de Pedro-Cuesta, Martínez-Mart’in, Rábano, Ruiz-Tovar, Alcalde-Cabero and Calero. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
de Pedro-Cuesta, Jesús Martínez-Martín, Pablo Rábano, Alberto Ruiz-Tovar, María Alcalde-Cabero, Enrique Calero, Miguel |
spellingShingle |
de Pedro-Cuesta, Jesús Martínez-Martín, Pablo Rábano, Alberto Ruiz-Tovar, María Alcalde-Cabero, Enrique Calero, Miguel Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features |
author_facet |
de Pedro-Cuesta, Jesús Martínez-Martín, Pablo Rábano, Alberto Ruiz-Tovar, María Alcalde-Cabero, Enrique Calero, Miguel |
author_sort |
de Pedro-Cuesta, Jesús |
title |
Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features |
title_short |
Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features |
title_full |
Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features |
title_fullStr |
Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features |
title_full_unstemmed |
Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features |
title_sort |
etiologic framework for the study of neurodegenerative disorders as well as vascular and metabolic comorbidities on the grounds of shared epidemiologic and biologic features |
description |
Background: During the last two decades, protein aggregation at all organismal levels, from viruses to humans, has emerged from a neglected area of protein science to become a central issue in biology and biomedicine. This article constitutes a risk-based review aimed at supporting an etiologic scenario of selected, sporadic, protein-associated, i.e., conformational, neurodegenerative disorders (NDDs), and their vascular- and metabolic-associated ailments. |
publisher |
Frontiers Media S.A. |
publishDate |
2016 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904010/ |
_version_ |
1613593243930329088 |