In Vitro Intestinal Permeability Studies and Pharmacokinetic Evaluation of Famotidine Microemulsion for Oral Delivery
The absolute bioavailability of famotidine after oral administration is about 40–45% and absorbance only in the initial part of small intestine may be due to low intestinal permeability. Hence, an olive oil based microemulsion formulation with Tween-80 as surfactant and PEG-400 as cosurfactant was d...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897392/ |