Loss of ATF3 Promotes Hormone-induced Prostate Carcinogenesis and the Emergence of CK5+CK8+ Epithelial Cells

Steroid sex hormones can induce prostate carcinogenesis, and are thought to contribute to the development of prostate cancer during aging. However, the mechanism for hormone-induced prostate carcinogenesis remains elusive. Here we report that activating transcription factor 3 (ATF3) – a broad stress...

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Bibliographic Details
Main Authors: Wang, Ziyan, Kim, Jaejik, Teng, Yong, Ding, Han-Fei, Zhang, Junran, Hai, Tsonwin, Cowell, John K., Yan, Chunhong
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853303/