Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway

Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway

Resistance to oxaliplatin (OXA) is a complex process affecting the outcomes of metastatic colorectal cancer (CRC) patients treated with this drug. De-regulation of the NF-κB signalling pathway has been proposed as an important mechanism involved in this phenomenon. Here, we show that NF-κB was hyper...

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Bibliographic Details
Main Authors: Ruiz de Porras, Vicenç, Bystrup, Sara, Martínez-Cardús, Anna, Pluvinet, Raquel, Sumoy, Lauro, Howells, Lynne, James, Mark I., Iwuji, Chinenye, Manzano, José Luis, Layos, Laura, Bugés, Cristina, Abad, Albert, Martínez-Balibrea, Eva
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835769/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835769/

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