Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities

Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities

Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased pathogenic potential of these strains has been attributed to several factors but is still poorly understood. During a C. difficile outbreak, a strain from this clade was f...

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Bibliographic Details
Main Authors: Quesada-Gómez, Carlos, López-Ureña, Diana, Chumbler, Nicole, Kroh, Heather K., Castro-Peña, Carolina, Rodríguez, César, Orozco-Aguilar, Josué, González-Camacho, Sara, Rucavado, Alexandra, Guzmán-Verri, Caterina, Lawley, Trevor D., Lacy, D. Borden, Chaves-Olarte, Esteban
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771349/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771349/

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