Expression of Interferon Lambda 4 Is Associated with Reduced Proliferation and Increased Cell Death in Human Hepatic Cells

Expression of Interferon Lambda 4 Is Associated with Reduced Proliferation and Increased Cell Death in Human Hepatic Cells

Interferon lambda 4 (IFN-λ4) is a novel type-III interferon that can be generated only in individuals carrying a ΔG frame-shift allele of an exonic genetic variant (rs368234815-ΔG/TT). The rs368234815-ΔG allele is strongly associated with decreased clearance of hepatitis C virus (HCV) infection. Her...

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Bibliographic Details
Main Authors: Onabajo, Olusegun O., Porter-Gill, Patricia, Paquin, Ashley, Rao, Nina, Liu, Luyang, Tang, Wei, Brand, Nathan, Prokunina-Olsson, Ludmila
Format: Online
Language:English
Published: Mary Ann Liebert, Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642834/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642834/

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