Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation

The tumour suppressor Merlin, encoded by the gene NF2, is frequently mutated in the autosomal dominant disorder neurofibromatosis type II, characterised primarily by the development of schwannoma and other glial cell tumours. However, NF2 is expressed in virtually all analysed human and rodent organ...

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Bibliographic Details
Main Authors: Zoch, Ansgar, Mayerl, Steffen, Schulz, Alexander, Greither, Thomas, Frappart, Lucien, Rübsam, Juliane, Heuer, Heike, Giovannini, Marco, Morrison, Helen
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530865/