CXCL8 and CCL20 Enhance Osteoclastogenesis via Modulation of Cytokine Production by Human Primary Osteoblasts

Generalized osteoporosis is common in patients with inflammatory diseases, possibly because of circulating inflammatory factors that affect osteoblast and osteoclast formation and activity. Serum levels of the inflammatory factors CXCL8 and CCL20 are elevated in rheumatoid arthritis, but whether the...

Full description

Bibliographic Details
Main Authors: Pathak, Janak L., Bakker, Astrid D., Verschueren, Patrick, Lems, Willem F., Luyten, Frank P., Klein-Nulend, Jenneke, Bravenboer, Nathalie
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477884/