Loss of ATF3 Promotes Akt Activation and Prostate Cancer Development in a Pten Knockout Mouse Model

Activating transcription factor 3 (ATF3) responds to diverse cellular stresses, and regulates oncogenic activities (e.g., proliferation, survival and migration) through direct transcriptional regulation or protein-protein interactions. Although aberrant ATF3 expression is frequently found in human c...

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Bibliographic Details
Main Authors: Wang, Ziyan, Xu, Dong, Ding, Han-Fei, Kim, Jaejik, Zhang, Junran, Hai, Tsonwin, Yan, Chunhong
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476969/