HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patients

HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patients

Human breast tumors harbor supernumerary centrosomes in almost 80% of tumor cells. Although amplified centrosomes compromise cell viability via multipolar spindles resulting in death-inducing aneuploidy, cancer cells tend to cluster extra centrosomes during mitosis. As a result cancer cells display...

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Bibliographic Details
Main Authors: Pannu, Vaishali, Rida, Padmashree C.G., Ogden, Angela, Turaga, Ravi Chakra, Donthamsetty, Shashikiran, Bowen, Nathan J., Rudd, Katie, Gupta, Meenakshi V., Reid, Michelle D., Cantuaria, Guilherme, Walczak, Claire E., Aneja, Ritu
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467423/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467423/

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