Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling

Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling

O-glycosylation is a common protein modification. Aberrant O-glycosylation is associated with many cancers. GALNT1 is a GalNAc-transferase that initiates protein O-glycosylation. We found that GALNT1 is frequently up-regulated in hepatocellular carcinoma (HCC) and is associated with poor patient sur...

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Bibliographic Details
Main Authors: Huang, Miao-Juei, Hu, Rey-Heng, Chou, Chih-Hsing, Hsu, Chia-Lang, Liu, Ya-Wen, Huang, John, Hung, Ji-Shiang, Lai, I-Rue, Juan, Hsueh-Fen, Yu, Sung-Liang, Wu, Yao-Ming, Huang, Min-Chuan
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467392/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467392/

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