Repulsive Guidance Molecule is a structural bridge between Neogenin and Bone Morphogenetic Protein

Repulsive guidance molecules (RGMs) control crucial processes spanning cell motility, adhesion, immune cell regulation and systemic iron metabolism. RGMs signal via two fundamental signaling cascades: the Neogenin (NEO1) and the Bone Morphogenetic Protein (BMP) pathways. Here, we report crystal stru...

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Bibliographic Details
Main Authors: Healey, Eleanor G., Bishop, Benjamin, Elegheert, Jonathan, Bell, Christian H., Padilla-Parra, Sergi, Siebold, Christian
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456160/