Structure-based functional identification of Helicobacter pylori HP0268 as a nuclease with both DNA nicking and RNase activities

Structure-based functional identification of Helicobacter pylori HP0268 as a nuclease with both DNA nicking and RNase activities

HP0268 is a conserved, uncharacterized protein from Helicobacter pylori. Here, we determined the solution structure of HP0268 using three-dimensional nuclear magnetic resonance (NMR) spectroscopy, revealing that this protein is structurally most similar to a small MutS-related (SMR) domain that exhi...

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Bibliographic Details
Main Authors: Lee, Ki-Young, Lee, Kyu-Yeon, Kim, Ji-Hun, Lee, In-Gyun, Lee, Sung-Hee, Sim, Dae-Won, Won, Hyung-Sik, Lee, Bong-Jin
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446426/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446426/

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