Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium
To estimate the prevalence of refractive error in adults across Europe. Refractive data (mean spherical equivalent) collected between 1990 and 2013 from fifteen population-based cohort and cross-sectional studies of the European Eye Epidemiology (E3) Consortium were combined in a random effects met...
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| Format: | Online |
| Language: | English |
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Springer Netherlands
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385146/ |
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pubmed-43851462015-04-08 Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium Williams, Katie M. Verhoeven, Virginie J. M. Cumberland, Phillippa Bertelsen, Geir Wolfram, Christian Buitendijk, Gabriëlle H. S. Hofman, Albert van Duijn, Cornelia M. Vingerling, Johannes R. Kuijpers, Robert W. A. M. Höhn, René Mirshahi, Alireza Khawaja, Anthony P. Luben, Robert N. Erke, Maja Gran von Hanno, Therese Mahroo, Omar Hogg, Ruth Gieger, Christian Cougnard-Grégoire, Audrey Anastasopoulos, Eleftherios Bron, Alain Dartigues, Jean-François Korobelnik, Jean-François Creuzot-Garcher, Catherine Topouzis, Fotis Delcourt, Cécile Rahi, Jugnoo Meitinger, Thomas Fletcher, Astrid Foster, Paul J. Pfeiffer, Norbert Klaver, Caroline C. W. Hammond, Christopher J. Ophthalmic Epidemiology To estimate the prevalence of refractive error in adults across Europe. Refractive data (mean spherical equivalent) collected between 1990 and 2013 from fifteen population-based cohort and cross-sectional studies of the European Eye Epidemiology (E3) Consortium were combined in a random effects meta-analysis stratified by 5-year age intervals and gender. Participants were excluded if they were identified as having had cataract surgery, retinal detachment, refractive surgery or other factors that might influence refraction. Estimates of refractive error prevalence were obtained including the following classifications: myopia ≤−0.75 diopters (D), high myopia ≤−6D, hyperopia ≥1D and astigmatism ≥1D. Meta-analysis of refractive error was performed for 61,946 individuals from fifteen studies with median age ranging from 44 to 81 and minimal ethnic variation (98 % European ancestry). The age-standardised prevalences (using the 2010 European Standard Population, limited to those ≥25 and <90 years old) were: myopia 30.6 % [95 % confidence interval (CI) 30.4–30.9], high myopia 2.7 % (95 % CI 2.69–2.73), hyperopia 25.2 % (95 % CI 25.0–25.4) and astigmatism 23.9 % (95 % CI 23.7–24.1). Age-specific estimates revealed a high prevalence of myopia in younger participants [47.2 % (CI 41.8–52.5) in 25–29 years-olds]. Refractive error affects just over a half of European adults. The greatest burden of refractive error is due to myopia, with high prevalence rates in young adults. Using the 2010 European population estimates, we estimate there are 227.2 million people with myopia across Europe. Springer Netherlands 2015-03-18 2015 /pmc/articles/PMC4385146/ /pubmed/25784363 http://dx.doi.org/10.1007/s10654-015-0010-0 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Williams, Katie M. Verhoeven, Virginie J. M. Cumberland, Phillippa Bertelsen, Geir Wolfram, Christian Buitendijk, Gabriëlle H. S. Hofman, Albert van Duijn, Cornelia M. Vingerling, Johannes R. Kuijpers, Robert W. A. M. Höhn, René Mirshahi, Alireza Khawaja, Anthony P. Luben, Robert N. Erke, Maja Gran von Hanno, Therese Mahroo, Omar Hogg, Ruth Gieger, Christian Cougnard-Grégoire, Audrey Anastasopoulos, Eleftherios Bron, Alain Dartigues, Jean-François Korobelnik, Jean-François Creuzot-Garcher, Catherine Topouzis, Fotis Delcourt, Cécile Rahi, Jugnoo Meitinger, Thomas Fletcher, Astrid Foster, Paul J. Pfeiffer, Norbert Klaver, Caroline C. W. Hammond, Christopher J. |
| spellingShingle |
Williams, Katie M. Verhoeven, Virginie J. M. Cumberland, Phillippa Bertelsen, Geir Wolfram, Christian Buitendijk, Gabriëlle H. S. Hofman, Albert van Duijn, Cornelia M. Vingerling, Johannes R. Kuijpers, Robert W. A. M. Höhn, René Mirshahi, Alireza Khawaja, Anthony P. Luben, Robert N. Erke, Maja Gran von Hanno, Therese Mahroo, Omar Hogg, Ruth Gieger, Christian Cougnard-Grégoire, Audrey Anastasopoulos, Eleftherios Bron, Alain Dartigues, Jean-François Korobelnik, Jean-François Creuzot-Garcher, Catherine Topouzis, Fotis Delcourt, Cécile Rahi, Jugnoo Meitinger, Thomas Fletcher, Astrid Foster, Paul J. Pfeiffer, Norbert Klaver, Caroline C. W. Hammond, Christopher J. Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium |
| author_facet |
Williams, Katie M. Verhoeven, Virginie J. M. Cumberland, Phillippa Bertelsen, Geir Wolfram, Christian Buitendijk, Gabriëlle H. S. Hofman, Albert van Duijn, Cornelia M. Vingerling, Johannes R. Kuijpers, Robert W. A. M. Höhn, René Mirshahi, Alireza Khawaja, Anthony P. Luben, Robert N. Erke, Maja Gran von Hanno, Therese Mahroo, Omar Hogg, Ruth Gieger, Christian Cougnard-Grégoire, Audrey Anastasopoulos, Eleftherios Bron, Alain Dartigues, Jean-François Korobelnik, Jean-François Creuzot-Garcher, Catherine Topouzis, Fotis Delcourt, Cécile Rahi, Jugnoo Meitinger, Thomas Fletcher, Astrid Foster, Paul J. Pfeiffer, Norbert Klaver, Caroline C. W. Hammond, Christopher J. |
| author_sort |
Williams, Katie M. |
| title |
Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium |
| title_short |
Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium |
| title_full |
Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium |
| title_fullStr |
Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium |
| title_full_unstemmed |
Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium |
| title_sort |
prevalence of refractive error in europe: the european eye epidemiology (e3) consortium |
| description |
To estimate the prevalence of refractive error in adults across Europe. Refractive data (mean spherical equivalent) collected between 1990 and 2013 from fifteen population-based cohort and cross-sectional studies of the European Eye Epidemiology (E3) Consortium were combined in a random effects meta-analysis stratified by 5-year age intervals and gender. Participants were excluded if they were identified as having had cataract surgery, retinal detachment, refractive surgery or other factors that might influence refraction. Estimates of refractive error prevalence were obtained including the following classifications: myopia ≤−0.75 diopters (D), high myopia ≤−6D, hyperopia ≥1D and astigmatism ≥1D. Meta-analysis of refractive error was performed for 61,946 individuals from fifteen studies with median age ranging from 44 to 81 and minimal ethnic variation (98 % European ancestry). The age-standardised prevalences (using the 2010 European Standard Population, limited to those ≥25 and <90 years old) were: myopia 30.6 % [95 % confidence interval (CI) 30.4–30.9], high myopia 2.7 % (95 % CI 2.69–2.73), hyperopia 25.2 % (95 % CI 25.0–25.4) and astigmatism 23.9 % (95 % CI 23.7–24.1). Age-specific estimates revealed a high prevalence of myopia in younger participants [47.2 % (CI 41.8–52.5) in 25–29 years-olds]. Refractive error affects just over a half of European adults. The greatest burden of refractive error is due to myopia, with high prevalence rates in young adults. Using the 2010 European population estimates, we estimate there are 227.2 million people with myopia across Europe.
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| publisher |
Springer Netherlands |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385146/ |
| _version_ |
1613207608869519360 |