Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

HIV protease converts procaspase 8 into Casp8p41, which binds and activates Bak to induce cell death in infected CD4 T cells.

Bibliographic Details
Main Authors: Sainski, Amy M., Dai, Haiming, Natesampillai, Sekar, Pang, Yuan-Ping, Bren, Gary D., Cummins, Nathan W., Correia, Cristina, Meng, X. Wei, Tarara, James E., Ramirez-Alvarado, Marina, Katzmann, David J., Ochsenbauer, Christina, Kappes, John C., Kaufmann, Scott H., Badley, Andrew D.
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178959/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178959/

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