Ornithine cyclodeaminase/μ-crystallin homolog from the hyperthermophilic archaeon Thermococcus litoralis functions as a novel Δ1-pyrroline-2-carboxylate reductase involved in putative trans-3-hydroxy-l-proline metabolism

•Ornithine cyclodeaminase homolog from an archeon was characterized biochemically.•This protein functions as a novel Δ1-pyrroline-2-carboxylate reductase.•This enzyme is probably involved in trans-3-hydroxy-l-proline metabolism as in bacteria and mammals.

Bibliographic Details
Main Authors: Watanabe, Seiya, Tozawa, Yuzuru, Watanabe, Yasuo
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141209/