RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis

RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis

Rheumatoid arthritis (RA) significantly affects quality of life. We recently cloned synoviolin, a RING-type E3 ubiquitin ligase implicated in the endoplasmic reticulum-associated degradation (ERAD) pathway. Synoviolin is highly expressed in rheumatoid synovial cells and may be involved in the pathog...

Full description

Bibliographic Details
Main Authors: YAGISHITA, NAOKO, ARATANI, SATOKO, LEACH, CRAIG, AMANO, TETSUYA, YAMANO, YOSHIHISA, NAKATANI, KO, NISHIOKA, KUSUKI, NAKAJIMA, TOSHIHIRO
Format: Online
Language:English
Published: D.A. Spandidos 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042867/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042867/

Similar Items