Shotgun Proteomics and Biomarker Discovery
Coupling large-scale sequencing projects with the amino acid sequence information that can be gleaned from tandem mass spectrometry (MS/MS) has made it much easier to analyze complex mixtures of proteins. The limits of this “shotgun” approach, in which the protein mixture is proteolytically digested...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
IOS Press
2002
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851423/ |