Decreased Copper in Alzheimer's Disease Brain Is Predominantly in the Soluble Extractable Fraction

Alzheimer's disease (AD) is the leading cause of dementia and represents a significant burden on the global economy and society. The role of transition metals, in particular copper (Cu), in AD has become of significant interest due to the dyshomeostasis of these essential elements, which can im...

Full description

Bibliographic Details
Main Authors: Rembach, Alan, Hare, Dominic J., Lind, Monica, Fowler, Christopher J., Cherny, Robert A., McLean, Catriona, Bush, Ashley I., Masters, Colin L., Roberts, Blaine R.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818847/