BMP Receptor 1A Determines the Cell Fate of the Postnatal Growth Plate

Bone morphogenic proteins (BMPs) are critical for both chondrogenesis and osteogenesis. Previous studies reported that embryos deficient in Bmp receptor (Bmpr)1a or Bmpr1b in cartilage display subtle skeletal defects; however, double mutant embryos develop severe skeletal defects, suggesting a funct...

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Bibliographic Details
Main Authors: Jing, Junjun, Ren, Yinshi, Zong, Zhaowen, Liu, Chuanju, Kamiya, Nobuhiro, Mishina, Yuji, Liu, Ying, Zhou, Xuedong, Feng, Jian Q.
Format: Online
Language:English
Published: Ivyspring International Publisher 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807016/