A Fully Human Inhibitory Monoclonal Antibody to the Wnt Receptor RYK

RYK is an unusual member of the receptor tyrosine kinase (RTK) family that is classified as a putative pseudokinase. RYK regulates fundamental biological processes including cell differentiation, migration and target selection, axon outgrowth and pathfinding by transducing signals across the plasma...

Full description

Bibliographic Details
Main Authors: Halford, Michael M., Macheda, Maria L., Parish, Clare L., Takano, Elena A., Fox, Stephen, Layton, Daniel, Nice, Edouard, Stacker, Steven A.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776778/