Process optimization and evaluation of novel baicalin solid nanocrystals
The objective of this study was to prepare baicalin solid nanocrystals (BCN-SNS) to enhance oral bioavailability of baicalin. A Box–Behnken design approach was used for process optimization. The physicochemical properties and pharmacokinetics of the optimal BCN-SNS were investigated. Multiple linear...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Dove Medical Press
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746734/ |